DRSC/TRiP Functional Genomics Resources

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Protein Alignment wry and jag2b

DIOPT Version :9

Sequence 1:NP_995611.2 Gene:wry / 33361 FlyBaseID:FBgn0051665 Length:1157 Species:Drosophila melanogaster
Sequence 2:NP_571937.1 Gene:jag2b / 140422 ZFINID:ZDB-GENE-011128-3 Length:1254 Species:Danio rerio


Alignment Length:542 Identity:154/542 - (28%)
Similarity:208/542 - (38%) Gaps:162/542 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   549 CEIPNVPQDSHLWRGNETHELLLPIVTTEHCKPDEHCVPN--VLTWRGEAEIQSGDILIVEINDA 611
            |.:|...:.::.|:|....|          |.|...|:..  |:.|:...|...|.:|.    |.
Zfish   248 CAVPGECKCNYGWQGQFCDE----------CLPYPGCLHGTCVMPWQCTCEKNWGGLLC----DK 298

  Fly   612 MLN--PSHEP-------------------------NNTSSAVHATQVYQVTRSG--HE------- 640
            .||  .:|.|                         .|...|.||.........|  ||       
Zfish   299 DLNYCGTHHPCVNGGTCMNSEPDEYNCACPEGYSGKNCEIAEHACVSNPCANGGTCHEVPTGFEC 363

  Fly   641 HC-----------DVTEGVLLDITPLVVDGRKLVTLYDKDLTEGVNLL-----------IVVSEL 683
            ||           |:.|   ...:|....|..:      ||..|...:           |..:|.
Zfish   364 HCPPGWEGPTCAKDMDE---CASSPCAQGGTCI------DLENGFECVCPPQWVGKTCQIDANEC 419

  Fly   684 WGAQCVRLKVTTKTDNC----------------GENAD-----CSGKGVCYSNSGMEE-----YE 722
            .|..||      ...:|                |:|.|     |.|:  |.:.:..:|     |.
Zfish   420 MGKPCV------NAHSCKNMIGGYHCDCFQGWAGQNCDINLNGCHGQ--CQNGATCKELVHGGYH 476

  Fly   723 CQCCSGFAGPHCE-EIDACNPSPCTNNGIC-VDLSQGHEGNSYQCLCPYGYAGKNCQYES----D 781
            |||.:||.|.||| ..:.|...||.|.|.| |.|      :|:.|.||..|||..|:.||    :
Zfish   477 CQCPAGFVGLHCEVSRNKCASGPCQNGGRCHVIL------DSFVCECPSNYAGMLCEVESLSHPN 535

  Fly   782 PCNPAECMNGGSCVGNSTHFRCDCAPGFTGPLCQHSLNECESSPC-------------------- 826
            ||.|..|.|...|......|.|.|...:.|..|::..:.|:.:||                    
Zfish   536 PCEPNPCQNTALCYSLPGDFYCACPEDYEGKTCENRKDHCKMTPCQVIDSCTIAVASNSSDGGVR 600

  Fly   827 --------VHGICVDQEDG-FRCFCQPGFAGELCNFEYNECESNPCQNGGECIDHIGSYECRCTK 882
                    .||.|:.|..| |.|.|:.||.|..|:...|:|.||||:|||.|||.|.|::|.|..
Zfish   601 HINSNVCGPHGRCISQPGGNFTCTCELGFTGTYCHENVNDCVSNPCRNGGTCIDGISSFQCFCPD 665

  Fly   883 GFSGNRCQIKVDFCANKPCPEGHRCIDHGNDFSCECPGGRNGPDCNQMPRTYFQQCNVNPCTHGG 947
            |:.|:.|.|.|:.|:..||..|..|:|..|||.|||..|..|..|:...    .||:.:.|::||
Zfish   666 GWEGDLCSINVNECSRSPCKNGGHCVDLVNDFYCECANGWKGKTCHSRE----SQCDSSTCSNGG 726

  Fly   948 TCWSSGDSFYCACRPGYTGTMC 969
            ||:..||:|.|||.||:.|:.|
Zfish   727 TCYDHGDAFRCACPPGWEGSTC 748

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wryNP_995611.2 EGF_CA 737..777 CDD:238011 15/40 (38%)
EGF 783..812 CDD:278437 8/28 (29%)
EGF_CA 819..851 CDD:238011 14/60 (23%)
EGF_CA 856..890 CDD:238011 18/33 (55%)
EGF_CA 893..927 CDD:238011 15/33 (45%)
EGF_CA <941..970 CDD:238011 15/29 (52%)
jag2bNP_571937.1 MNNL 28..101 CDD:284966
DSL 170..232 CDD:279722
EGF_CA 299..337 CDD:238011 5/37 (14%)
EGF_CA <346..374 CDD:238011 5/27 (19%)
EGF_CA 377..413 CDD:238011 7/44 (16%)
EGF_CA 415..450 CDD:238011 6/40 (15%)
EGF_CA 458..489 CDD:238011 11/32 (34%)
EGF_CA 493..527 CDD:238011 15/39 (38%)
EGF_CA 535..569 CDD:238011 10/33 (30%)
EGF_CA 637..672 CDD:238011 18/34 (53%)
EGF_CA 675..710 CDD:238011 15/34 (44%)
EGF 756..786 CDD:278437
EGF_CA 790..825 CDD:238011
EGF_CA 828..864 CDD:238011
VWC_out 873..944 CDD:214565
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 51 1.000 Domainoid score I11560
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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