Protein Alignment wry and Delta

DIOPT Version :10

• Sequence 1: NP_995611.2
• Gene: wry / 33361
• FlyBaseID: FBgn0051665
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: XP_061512000.1
• Gene: Delta / 1279687
• VectorBaseID: AGAMI1_007305
• Length: 1025
• Species: Anopheles gambiae
• Alignment Length: 929
• Identity: 201/929 - (21%)
• Similarity: 310/929 - (33%)
• Gaps: 315/929 - (33%)

  Fly   374 EFSTTKFYNSKELYNEMLLHNKRKLMKAAKAEGSPIKSAEDTTRATSSNVTPEGKTFGPTTTTAA 438
            |.....|.|.|.:.     ||::...:.|.|:|..|.:.:...||...:......|..|.|   .
Mosquito    28 ELELRYFQNEKSID-----HNEKCCSEKADAQGRCIGTCKTRFRACLKHYQATIDTTSPCT---F 84

  Fly   439 GSTATTTAESTT---TAATTTRLPATTTGKYQKEL---KRAKLLLKALTPPKSVDKSTASPSSTT 497
            |...|...|.||   ||.:..:...|...::..|.   ....|:::|.             ..|.
Mosquito    85 GDVITPVLEGTTLNFTAISGAKEGFTNPIRFPFEFGWPGYFTLIIEAW-------------HDTN 136

  Fly   498 STSTSTTTTMATLLATARTRPSAANPTKTASKPIARPRILSRLQEKINS----------LECEIP 552
            .|:|.:..|:.:.|:..|....:|:                .:::..||          :.|: |
Mosquito   137 ETTTRSPGTLISRLSIQRILEVSAD----------------WMEDSYNSSHTMIRYAFRVTCD-P 184

  Fly   553 NV----------PQDSHLWRGNETHELLLPIVTTEHCKP--DEHCVPNVLTWRGE----AEIQSG 601
            |.          .:|...  |:.|            |.|  :..|:..   |.||    |:...|
Mosquito   185 NYYGAGCANLCRKRDDQF--GHYT------------CSPIGERVCLSG---WLGEYCTVAQCTPG 232

  Fly   602 DILIVEINDAMLNPSHEPNNTSSAVHATQVYQVTRSGH-----EHCDVTEGVLLDITPLVVDGRK 661
                     .:....::||..           :.:||.     :.|:...|.|....
Mosquito   233 ---------CLHGHCNKPNEC-----------ICQSGWKGPLCDECEPYPGCLHGTC-------- 269

  Fly   662 LVTLYDKDLTEGVNLLIVVSELWGAQCVRLKVTTKTDNCGENADCSGKGVCYSNSGMEEYECQCC 726
                  |...|     .:..|.||.    |......:.|..:..|...|.|: |:|...|.|||.
Mosquito   270 ------KKPWE-----CICKEGWGG----LFCNQDLNYCTNHKPCLNGGTCF-NTGQGLYTCQCR 318

  Fly   727 SGFAGPHCE-EIDACNPSPCTNNGICVDLSQGH-----EGNSYQCLCPYGYAGKNCQYESDPCNP 785
            .|:.|..|| .|.:|:..||.:...|.....|.     :|..|||.|..|:.|::|:.|:..|..
Mosquito   319 PGYKGTECELSITSCSDHPCLHGATCTSTVDGETSMDADGRKYQCHCAKGWMGRHCEREAITCAE 383

  Fly   786 AECMNGGSCV----------GNSTHFRCDCAPGFTGPLCQHSLNECESSPCVH-GIC-------- 831
            ..| :.|:||          ..|.:|||||.||::|..|:....||.|:.|.: |.|
Mosquito   384 KPC-HQGTCVDVTPSSSSSSSTSANFRCDCPPGYSGTACEIKSGECYSNYCANGGTCHVAGSSSS 447

  Fly   832 ----------------------------VDQEDG----FRCFCQPGFAGELCNFEYNECESNPCQ 864
                                        .:..||    ..|.|..||.|:.|....::|..|.|.
Mosquito   448 SSASSSIMASSQSSSSSSLSALFGSGNSNNNNDGGIGMLMCLCPDGFVGDRCEENVDDCVGNLCL 512

  Fly   865 NGGECIDHIGSYECRCTKGFSGNRCQIKVDFCANKPCPEGHRCIDHGNDFSCECPGGRNGPDCNQ 929
            |||.|:|....::|:|..||.|..|:.|||.|..|||..|..|.:..||:.|:|..|..|.||:
Mosquito   513 NGGTCVDADNHFKCQCVPGFIGTHCEEKVDLCLTKPCANGGICTNLENDYRCQCRAGFTGKDCS- 576

  Fly   930 MPRTYFQQCNVNPCTHGGTCWSSGDSFYCACRPGYTGTMCEDEFVV----ETVVSSSEFIVD--- 987
               ....:|:..||.:||||.:..:|:.|.|..||.|..||:|...    :..:..|||...
Mosquito   577 ---ADVDECHSAPCRNGGTCINRVNSYQCVCAGGYRGHSCEEESATVIQRDADIEGSEFHHHHHH 638

  Fly   988 -------------DANARNFNDKTFGSSVVLKSPIELHNAYFAAGVLAAAIFIVAVVVTIC---- 1035
                         |:::|..:..:.|..|::        |.|:  :....:..:|..:.||
Mosquito   639 PQQQQRHSGGEGVDSSSRTADGLSSGQIVLI--------AMFS--ISTPLLAFIATTIVICLKRK 693

  Fly  1036 ---------------------------------HCKVNQTYRK----------FSTRSTSFIPIL 1057
                                             |.:..|.:::          .|:.|||...:|
Mosquito   694 RQREQEKDDAEARKQNEQNASHNLSASSHHHHHHLQQQQQHQQQQQLHHQQSSSSSSSTSSGALL 758

  Fly  1058 GFSRRPKVQGKLNK---HWLSGKGATATSS---------------------TNIVAPP------- 1091
            ..|.:.:.|.:.:.   :.|...|....||                     .|:.:||
Mosquito   759 HSSSQQQQQQQYHNGFHNHLQSSGQKRNSSNTLSNFDSSHHMIKNTWDKSINNMPSPPTTASGSG 823

  Fly  1092 ---------GGPRAGGAAG 1101
                     ||..|||..|
Mosquito   824 VSSSGGGGTGGCSAGGVGG 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wry	NP_995611.2	EGF_CA	737..777	CDD:238011	13/44 (30%)
		EGF	783..812	CDD:394967	13/38 (34%)
		EGF_CA	819..851	CDD:238011	13/72 (18%)
		EGF_CA	856..890	CDD:238011	13/33 (39%)
		EGF_CA	893..927	CDD:238011	14/33 (42%)
		EGF	938..966	CDD:394967	12/27 (44%)
Delta	XP_061512000.1	None