Protein Alignment wry and NOTCH2NLC

DIOPT Version :9

• Sequence 1: NP_995611.2
• Gene: wry / 33361
• FlyBaseID: FBgn0051665
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_001350942.1
• Gene: NOTCH2NLC / 100996717
• HGNCID: 53924
• Length: 293
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 101/311 - (32%)
• Similarity: 141/311 - (45%)
• Gaps: 60/311 - (19%)

  Fly   701 GENAD------CSGKGVCYSNSGMEEYECQCCSGFAGPHCEEIDACNPSPCTNNGICVDLSQGHE 759
            |:..|      |.|:  |:.:.........|..|:             .||.|.|:||..   |.
Human    18 GDREDARPAPLCCGR--CWRSGCAARPPRMCRDGY-------------EPCVNEGMCVTY---HN 64

  Fly   760 GNSYQCLCPYGYAGKNCQYESDPCNPAECMNGGSCV-----GNSTHFRCDCAPGFTGPLCQHSLN 819
            |..| |.||.|:.|:.||:. |||....|.|||:||     |.:|   |.||.||||..||:|.:
Human    65 GTGY-CKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKAT---CRCASGFTGEDCQYSTS 124

  Fly   820 E-C-ESSPCVH-GIC-VDQEDGFRCFCQPGFAGELCNFEYNECESNPCQNGGECIDHIGSYECRC 880
            . | .|.||:: |.| :...|.:.|.||.||.|:.|.:. :.|.|:||.||..|......:.|:|
Human   125 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKC 188

  Fly   881 TKGFSGNRCQIKVDFCANKP--CPEGHRCIDHGNDFSCECPGGRNGPDCNQMPRTYFQQCNVNPC 943
            ..||:|.:|:..|:.| :.|  |..|..|::....:.|:|..|..|..|:.:    :..|..:||
Human   189 LTGFTGQKCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSL----YVPCAPSPC 248

  Fly   944 THGGTCWSSGD-SFYCACRPGYTGTMCEDEFVVETVVSSSEFIVDDANARN 993
            .:||||..:|| :|.|.|.|             |||...:|....|....|
Human   249 VNGGTCRQTGDFTFECNCLP-------------ETVRRGTELWERDREVWN 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wry	NP_995611.2	EGF_CA	737..777	CDD:238011	14/39 (36%)
		EGF	783..812	CDD:278437	15/33 (45%)
		EGF_CA	819..851	CDD:238011	13/35 (37%)
		EGF_CA	856..890	CDD:238011	12/33 (36%)
		EGF_CA	893..927	CDD:238011	10/35 (29%)
		EGF_CA	<941..970	CDD:238011	12/29 (41%)
NOTCH2NLC	NP_001350942.1	EGF_CA	200..236	CDD:238011	10/36 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910