Protein Alignment wry and dner

DIOPT Version :10

• Sequence 1: NP_995611.2
• Gene: wry / 33361
• FlyBaseID: FBgn0051665
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_001269415.2
• Gene: dner / 100332110
• ZFINID: ZDB-GENE-130502-1
• Length: 745
• Species: Danio rerio
• Alignment Length: 631
• Identity: 182/631 - (28%)
• Similarity: 254/631 - (40%)
• Gaps: 147/631 - (23%)

  Fly   476 LLKALTPPKSVDKSTASPSSTTSTSTSTTTTMATLLATARTRPSAANPTKTASKPIARPRILSRL 540
            |.::|.|..:...:.|:|::||.....||....|          .|.||....:|.|..|:|..|
Zfish   142 LAESLVPEHATPATPATPATTTQVLQPTTVLTTT----------QAPPTLEPWQPRAGQRVLEIL 196

  Fly   541 ---QEKINSLECEIPNVPQDSHLWRGNETHELLLPIVTTEHCKPDEHCVPNVLTWRGE-AEIQSG 601
               |:..|..||                                       |.|..|| |.:.|.
Zfish   197 WDDQQITNEAEC---------------------------------------VSTAGGESAGMMSI 222

  Fly   602 DILIVEINDAMLNPSHEPNNTSSAVHATQVYQVTRSGHEHCDVTEGVLLDITPLVVDGRKLVTLY 666
            .:.:.|.....|    ..|.:.|||    :::|..||:|.|.|.:|.::    ......:.:.|.
Zfish   223 SLELAEETAVKL----VGNVSGSAV----LWRVGASGYEQCSVADGTIM----WFQQSSEGLVLP 275

  Fly   667 DKDLTEGVNLLIVVSELWGAQ----CVRLKVTTKTDNCGE------NADCSGKGVCYSNSGMEEY 721
            |:.|..|.|..|.|..:....    .:||.:..||:||.|      :..|||||.|.:.|.::.:
Zfish   276 DQSLPLGHNYFISVLHVGSPSGPEVTLRLHLLVKTNNCMEPGSAFSDPQCSGKGKCVTQSSVDTF 340

  Fly   722 ECQCCSGFAGPHCEEIDACNPSPCTNNGICVDLSQGHEGNSYQCLCPYGYAGKNCQ--------- 777
            .|:|..|::|..|||.|||:..||.|||.|.||.|..||.:|.|.|..|:.|:.||
Zfish   341 YCRCDDGYSGIFCEEFDACHLKPCENNGSCADLRQRDEGQNYTCTCQTGFEGERCQSLVDHCVSG 405

  Fly   778 ----------------------YES-------DPCNPAECMNGGSC--VGNSTHFRCDCAPGFTG 811
                                  |:.       |||....|.|..||  .|....|.|.|..||||
Zfish   406 PCRNGATCSSSLEGPHCYCAEGYQGIMCEQKIDPCASGPCHNNASCSPQGAGLGFSCTCPAGFTG 470

  Fly   812 PLCQHSLNECESSPCVHGICVDQEDGFRCFCQPGFAGELCNFEYNECESNPCQNGGECIDHIGSY 876
            |.|...::.|..:||.||||......:||.|.||:.|..|..|||||.|.||||...|.|.|.:|
Zfish   471 PTCAQLVDFCALNPCAHGICRSIGTSYRCLCVPGYHGLYCEEEYNECLSAPCQNYATCRDLINAY 535

  Fly   877 ECRCTKGFSGNRCQIKVDFCANKPCPEGHRCIDHGNDFSCECPGGRNGPDCNQMPRTYFQQCNVN 941
            ||.|...|:|..|:|..|.|....|..|..|...|.:.||.||.|..|.:|    .....:|..|
Zfish   536 ECICASQFTGKHCEIYKDPCLKLRCQNGGHCESGGRNASCVCPPGYMGENC----EVDVNECESN 596

  Fly   942 PCTHGGTCWSSGDSFYCACRPGYTGTMCEDEF---VVETVVSSSEFIVDDANARNFNDKTFGSSV 1003
            ||.|||||....:.:.|.|.||:.|..||...   :.:.|.|.:.
Zfish   597 PCHHGGTCIDQSNGYTCHCPPGWVGGSCEIHLQWKMAQPVDSLTN-------------------- 641

  Fly  1004 VLKSPIELHNAYFAAGVLAAAIFIVAVVVTICHCKVNQTYRKFSTR 1049
                 :..|:.|...|.|..|..::.:::.:..|::::...:.|:|
Zfish   642 -----MPRHSLYIIIGALCVAFVLMLIILIVGICRISRIEYQGSSR 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wry	NP_995611.2	EGF_CA	737..777	CDD:238011	19/39 (49%)
		EGF	783..812	CDD:394967	12/30 (40%)
		EGF_CA	819..851	CDD:238011	13/31 (42%)
		EGF_CA	856..890	CDD:238011	17/33 (52%)
		EGF_CA	893..927	CDD:238011	12/33 (36%)
		EGF	938..966	CDD:394967	13/27 (48%)
dner	NP_001269415.2	None