DRSC/TRiP Functional Genomics Resources

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Protein Alignment c-cup and Pgrmc2

DIOPT Version :9

Sequence 1:NP_608623.2 Gene:c-cup / 33360 FlyBaseID:FBgn0031367 Length:201 Species:Drosophila melanogaster
Sequence 2:NP_081834.1 Gene:Pgrmc2 / 70804 MGIID:1918054 Length:217 Species:Mus musculus


Alignment Length:146 Identity:35/146 - (23%)
Similarity:61/146 - (41%) Gaps:28/146 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 ESQPKDT----KGHDIVLLTLEELTAFDGS-SPSLPIYTALNGLIYDLSPGREKFSSHGPYSLLA 131
            |..|..|    |..|   .:||:|..:||: :|.  |..|:||.::|::.|.:.:...|||.:.|
Mouse    82 EESPAATLPRMKKRD---FSLEQLRQYDGARTPR--ILLAVNGKVFDVTKGSKFYGPAGPYGIFA 141

  Fly   132 GCNANKVLNIAC-------------SSMGVCAANVISRWEQSLRAEFKVVGYLVDADIDIISGSP 183
            |.:|::.|...|             |.:.......:..||...:.::..||.|:..     ...|
Mouse   142 GRDASRGLATFCLDKDALRDEYDDLSDLNAVQMESVREWEMQFKEKYDYVGRLLKP-----GEEP 201

  Fly   184 VKHTNSAIGEQMEKSD 199
            .::|:....:...|.|
Mouse   202 SEYTDEEDTKDHSKQD 217

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
c-cupNP_608623.2 Cyt-b5 87..>115 CDD:295147 11/28 (39%)
Pgrmc2NP_081834.1 Cyt-b5 96..194 CDD:278597 26/102 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 196..217 3/25 (12%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1110
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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