DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment c-cup and Cyb5d2

DIOPT Version :9

Sequence 1:	NP_608623.2	Gene:	c-cup / 33360	FlyBaseID:	FBgn0031367	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_001020097.2	Gene:	Cyb5d2 / 192986	MGIID:	2684848	Length:	263	Species:	Mus musculus

Alignment Length:	135	Identity:	31/135 - (22%)
Similarity:	52/135 - (38%)	Gaps:	20/135 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 IVLLTLEELTAFDGSSPSLPIYTALNGLIYDLSPGREKFSSHGPYSLLAGCNANKVL-------- 139
            |.|...|||..:.|......:|.||.|.:||:|.||..:.....||..||.:|::..
Mouse    35 IRLFLPEELARYRGGPGDPGLYLALLGRVYDVSSGRRHYEPGAHYSGFAGRDASRAFVTGDYSEA 99

  Fly   140 NIACSSMGVCAANVIS--RWEQSLRAEFKVVGYLV----------DADIDIISGSPVKHTNSAIG 192
            .:.....|:.::.:::  .|.......:..||.||          .:::..:.....|...:...
Mouse   100 GLVDDINGLSSSEILTLHNWLSFYEKNYVFVGRLVGRFYRKDGLPTSELTQVEAMVTKGMEANEQ 164

  Fly   193 EQMEK 197
            ||.||
Mouse   165 EQREK 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
c-cup	NP_608623.2	Cyt-b5	87..>115	CDD:295147	10/27 (37%)
Cyb5d2	NP_001020097.2	Cyt-b5	37..>91	CDD:278597	19/53 (36%)
Cyb5d2	NP_001020097.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	220..249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1110
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810