DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17712 and gfod2

DIOPT Version :9

Sequence 1:	NP_608619.1	Gene:	CG17712 / 33356	FlyBaseID:	FBgn0027597	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001025591.1	Gene:	gfod2 / 594979	XenbaseID:	XB-GENE-5740207	Length:	384	Species:	Xenopus tropicalis

Alignment Length:	385	Identity:	173/385 - (44%)
Similarity:	255/385 - (66%)	Gaps:	14/385 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LPGVGVFGTGEIANVLVPLLREKGFEVRAIWGRTLKEAKETATTQNVQFHTNVIDDVLLRKDVDL 66
            |||:||||||..|.||:.|||..||.:.|:||:|.:||||.|....:.|:|...|||||.::|||
Frog     4 LPGIGVFGTGNTARVLISLLRADGFSIEALWGKTDEEAKELAEEMGIPFYTCHTDDVLLHQEVDL 68

  Fly    67 VFIVCQPFLHAEISVKALGIGKHVVCDKPAGLHQQDALKMVRASQYYPTLISLVNHPLRFLPAFT 131
            |.|...|.|..:|:||||||||:|:|:|.|.  ..||..||:|::|||.|:|||.:.|||||||.
Frog    69 VCISIPPPLTRQIAVKALGIGKNVICEKAAS--SIDAFTMVKAARYYPKLMSLVGNALRFLPAFD 131

  Fly   132 HMRRCLQEELIGSIGDVVLMDVRVQMGTLFPEKYNWMCDAQMGGGALNLVGS-VVDLVTFLLQQQ 195
            .||:.:.|:  ..:|::.:.||||..|:|....|:|:||..||||.|:.:|: :|||:|.|..::
Frog   132 RMRQLILEQ--NYVGEIRICDVRVYGGSLLSSNYSWICDDLMGGGGLHTLGTYLVDLLTHLTNKR 194

  Fly   196 AIRVHGVLRSYTKTTPAINGIRQITAPDFCNFQMELASGTLVTVALHSHTVPAKAFSQEVLIYGS 260
            |.:|||.|:::.|...||:|||.:|:.|||.|||::..|...||.| :..:|. .|..||::.||
Frog   195 AEKVHGFLKTFVKQNEAISGIRYVTSDDFCFFQMQMTGGACSTVTL-NFNMPG-TFVHEVMVVGS 257

  Fly   261 KGHLVVRGGDLFVLKEGQPKEEAVYVD--VQDLHFATNNSLLPRPYIKGLCKMVGALKEAFGSKE 323
            .|.|||||.:||..|....:|:.:..|  .:::...::...:|.||:.|:..||.||:::|..:|
Frog   258 AGRLVVRGTELFGQKNSASEEKLLLSDPLTREIADISDFEKVPPPYLMGIAHMVKALRQSFQDQE 322

  Fly   324 S--SWVKAPVSTAATFEDGLYVQAVVEAIRKSNETRQWQRVQLS---TDSPLNHDQIIRY 378
            .  :|.:.|:|.|||||||||:|.||:||::||.:.:|:.|:|:   |||..|..::|::
Frog   323 DRRTWDQKPLSVAATFEDGLYMQRVVDAIKRSNRSGEWESVELTNDETDSNQNLSEVIQH 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17712	NP_608619.1	MviM	5..364	CDD:223745	164/363 (45%)
gfod2	NP_001025591.1	MviM	1..365	CDD:223745	167/366 (46%)
		GFO_IDH_MocA	7..118	CDD:279716	59/112 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	358..384		8/25 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	205	1.000	Domainoid score	I2857
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	325	1.000	Inparanoid score	I2448
OMA	1	1.010	-	-		QHG48581
OrthoDB	1	1.010	-	-		D356632at33208
OrthoFinder	1	1.000	-	-		FOG0001912
OrthoInspector	1	1.000	-	-		otm49191
Panther	1	1.100	-	-	LDO	PTHR43818
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2601
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080