Protein Alignment CG17712 and GFOD1

DIOPT Version :10

• Sequence 1: NP_608619.1
• Gene: CG17712 / 33356
• FlyBaseID: FBgn0027597
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_061861.1
• Gene: GFOD1 / 54438
• HGNCID: 21096
• Length: 390
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 179/400 - (44%)
• Similarity: 264/400 - (66%)
• Gaps: 31/400 - (7%)

  Fly     1 MLPGVGVFGTGEIANVLVPLLREKGFEVRAIWGRTLKEAKETATTQNVQFHTNVIDDVLLRKDVD 65
            ||||||||||...|.|::|||:::||.|:|:||||.:||:|.|...:|.|:|:.||:|||.:|||
Human     1 MLPGVGVFGTSLTARVIIPLLKDEGFAVKALWGRTQEEAEELAKEMSVPFYTSRIDEVLLHQDVD 65

  Fly    66 LVFIVCQPFLHAEISVKALGIGKHVVCDKPAGLHQQDALKMVRASQYYPTLISLVNHPLRFLPAF 130
            ||.|...|.|..:|:||.|||||:|:||:.|  ...||.:|..|:.|||.|:|::.:.|||||||
Human    66 LVCINLPPPLTRQIAVKTLGIGKNVICDRTA--TPLDAFRMTSAAHYYPKLMSIMGNVLRFLPAF 128

  Fly   131 THMRRCLQEELIGSIGDVVLMDVRVQMGTLFPEKYNWMCDAQMGGGALNLVGS-VVDLVTFLLQQ 194
            ..|::.::|   |.:|:.::.:|:|..|:|..:||||.||..||||.|:.||: ::||:|||..|
Human   129 VRMKQLIEE---GYVGEPLVCEVQVHGGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTGQ 190

  Fly   195 QAIRVHGVLRSYTKTTPAINGIRQITAPDFCNFQMELASGTLVTVALHSHTVPAKAFSQEVLIYG 259
            :|::|||:|:::.|.|..|.||||||:.|||.|||.|..|...||.| :..||.: |.|:|.:.|
Human   191 KAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTL-NFNVPGE-FKQDVTVVG 253

  Fly   260 SKGHLVVRGGDLFVLKEGQPKEEAVYVDVQDLHFAT--NNSLLPR--------PYIKGLCKMVGA 314
            |.|.|:..|.||:..:...|::|.:   |||   ||  :|||||.        ||::|..||:.|
Human   254 SAGRLLAVGTDLYGQRNSAPEQELL---VQD---ATPVSNSLLPEKAFSDIPSPYLRGTIKMMQA 312

  Fly   315 LKEAFGSKES--SWVKAPVSTAATFEDGLYVQAVVEAIRKSNETRQWQRVQLSTDSP-LNHDQII 376
            :::||..::.  :|...|::.||||:|.||...||:.|::|::|.:||.:.:.|:.| |:...:|
Human   313 VRQAFQDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKRSSQTGEWQNIAIMTEEPELSPAYLI 377

  Fly   377 ----RYARMS 382
                |.:|||
Human   378 SEAMRRSRMS 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17712	NP_608619.1	MviM	4..362	CDD:440437	168/370 (45%)
GFOD1	NP_061861.1	MviM	4..260	CDD:440437	129/262 (49%)