DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and ABCG39

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_176867.2	Gene:	ABCG39 / 843013	AraportID:	AT1G66950	Length:	1454	Species:	Arabidopsis thaliana

Alignment Length:	750	Identity:	175/750 - (23%)
Similarity:	307/750 - (40%)	Gaps:	185/750 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 SELSIDETSSTSSRGSCELTSKVTNDLNGFQSPNYHQAVAHANFDHCDPVDIQFADVRYTVKKFS 119
            :|.|:.|.:|:|::|          ...|...|             ..|:.:.|.:|.|.|...|
plant   825 TEGSVVELNSSSNKG----------PKRGMVLP-------------FQPLSLAFNNVNYYVDMPS 866

  Fly   120 FPERKFV---TKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCSTG-VSGDIRVNRKPM 180
            ..:.:.|   ..::|..:.|:||.|.|||::|.|||||:||::|::|..:.| :.|.|.::..|
plant   867 EMKAQGVEGDRLQLLRDVGGAFRPGILTALVGVSGAGKTTLMDVLAGRKTGGYIEGSISISGYP- 930

  Fly   181 APSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGLDHRYN 245
             .:...|.::..|..|:|:..|.:.|.|.::.:|.|:|...:....:...::.::.|:.|....|
plant   931 -KNQTTFARVSGYCEQNDIHSPHVTVYESLIYSAWLRLSTDIDIKTRELFVEEVMELVELKPLRN 994

  Fly   246 VPTG-----KLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVC 305
            ...|     .||..|:|||.||:||::||.::::||||:|||:.:.:..:..::.....|.|:||
plant   995 SIVGLPGVDGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVC 1059

  Fly   306 TIHQPSALIFEMFDKLYTVV-DGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEVAVGEHQR 369
            ||||||..|||.||:|..:. .|..:|.|                             ::|.|.:
plant  1060 TIHQPSIDIFESFDELLLMKRGGQVIYAG-----------------------------SLGHHSQ 1095

  Fly   370 DLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQFSSFDYV 434
            .|.|        |:|.|:                        .|.|.::   .:..|.: ..|..
plant  1096 KLVE--------YFEAVE------------------------GVPKIND---GYNPATW-MLDVT 1124

  Fly   435 KPSPQ-ELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELARPPNAIRSASFLMQYV-LL 497
            .||.: :::|:..:..|      :..|..:|     |.|.|  :|:.||...:...|..:|. ..
plant  1125 TPSMESQMSLDFAQIFS------NSSLYRRN-----QELIK--DLSTPPPGSKDVYFKTKYAQSF 1176

  Fly   498 MQRILICAKRNYFLL-------LARIFSHIFIGVVFGYLYMNVG---NNAQSVLGNYVYLYGSTL 552
            ..:...|..:.|:..       ..|....:.|||:||.::..:|   .|.|.:...:..:|.:.|
plant  1177 STQTKACFWKQYWSYWRHPQYNAIRFLMTVVIGVLFGLIFWQIGTKTENEQDLNNFFGAMYAAVL 1241

  Fly   553 LLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQSLCTAMYIIISVHLTGND 617
            .|.......|.....:|..:..||.....|...||.:|.::.||.:.::.|.:|.:|...:.|.:
plant  1242 FLGALNAATVQPAIAIERTVFYREKAAGMYSAIPYAISQVAVEIMYNTIQTGVYTLILYSMIGCN 1306

  Fly   618 ATDS--FRIYYFMLLGIMASLSAQAWGFFVGATLPTKLAVFLGPILAVMFSVFGFCTRYIDITPL 680
            .|.:  ...||:||..            |:..||...:.:.|.|    .:.:.|.|..:
plant  1307 WTMAKFLWFYYYMLTS------------FIYFTLYGMMLMALTP----NYQIAGICMSF------ 1349

  Fly   681 FRWMWHLSYFRAGFHGALNAIYGMDRPFLECPETAMYCHFRSPKVFLKYMMI--------SDVHM 737
            |..:|:|      |.|.|     :.||  :.|....:.::.:|..:..|.:|        |.||:
plant  1350 FLSLWNL------FSGFL-----IPRP--QIPIWWRWYYWATPVAWTLYGLITSQVGDKDSMVHI 1401

  Fly   738 S-------DCLILMGI--------VIGVMHVLTLI 757
            |       ..|:..|.        |:.|:|:..::
plant  1402 SGIGDIDLKTLLKEGFGFEHDFLPVVAVVHIAWIL 1436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	80/239 (33%)
		3a01204	123..765	CDD:273361	161/681 (24%)
		ABC2_membrane	497..698	CDD:279410	45/212 (21%)
ABCG39	NP_176867.2	PLN03140	14..1454	CDD:215599	175/749 (23%)
		ABC_trans_N	94..169	CDD:291196
		P-loop_NTPase	180..430	CDD:304359
		ABC2_membrane	531..737	CDD:279410
		PDR_assoc	744..810	CDD:285559
		ABCG_PDR_domain2	850..1088	CDD:213199	80/239 (33%)
		ABC2_membrane	1183..1388	CDD:279410	51/239 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910