DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and PEN3

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_176196.1	Gene:	PEN3 / 842281	AraportID:	AT1G59870	Length:	1469	Species:	Arabidopsis thaliana

Alignment Length:	660	Identity:	162/660 - (24%)
Similarity:	272/660 - (41%)	Gaps:	151/660 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 PVDIQFADVRYTVKKFSFPERKFVTK---EILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGF 164
            |:.:.|.||:|.|........:.||:   ::|.|:.|:||.|.|||:||.|||||:||::|::|.
plant   864 PLAMSFDDVKYFVDMPGEMRDQGVTETRLQLLKGVTGAFRPGVLTALMGVSGAGKTTLMDVLAGR 928

  Fly   165 CSTG-VSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKM 228
            .:.| :.||:|::..|..  .|.|.::..|..|.|:..||:.|.|.::.:|.|:|..:|.|..||
plant   929 KTGGYIEGDVRISGFPKV--QETFARISGYCEQTDIHSPQVTVRESLIFSAFLRLPKEVGKDEKM 991

  Fly   229 DLIKHILSLLGLDHRYNVPTG-----KLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSS 288
            ..:..::.|:.||...:...|     .||..|:|||.||:||::||.::::||||:|||:.:.:.
plant   992 MFVDQVMELVELDSLRDSIVGLPGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAI 1056

  Fly   289 CVALLKKLASQGHTIVCTIHQPSALIFEMFDKLYTVV-DGHCMYQGPV----RELVPFLADQQLV 348
            .:..::.....|.|:||||||||..|||.||:|..:. .|..:|.||:    .::|.:......|
plant  1057 VMRAVRNTVDTGRTVVCTIHQPSIDIFEAFDELMLMKRGGQVIYAGPLGQNSHKVVEYFESFPGV 1121

  Fly   349 --CPSYHNPADYLLEVAVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGK 411
              .|..:|||.::||.:           ..||..|.           |.|.|.|......:...|
plant  1122 SKIPEKYNPATWMLEAS-----------SLAAELKL-----------SVDFAELYNQSALHQRNK 1164

  Fly   412 AVVKTSEALAAFAAAQFSSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAG 476
            |:||
plant  1165 ALVK------------------------------------------------------------- 1168

  Fly   477 ELARPPNAIRSASFLMQYVL-LMQRILICAKRNYFLL-------LARIFSHIFIGVVFGYLYMNV 533
            ||:.||.......|..|:.. ...:...|..:.::..       |.|....:...::.|.::..:
plant  1169 ELSVPPAGASDLYFATQFSQNTWGQFKSCLWKQWWTYWRSPDYNLVRFIFTLATSLLIGTVFWQI 1233

  Fly   534 GNNAQS------VLGNYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLI 592
            |.|..:      |:|   .||.:.:.:.......|.....:|..:..||.....|...||.:|.:
plant  1234 GGNRSNAGDLTMVIG---ALYAAIIFVGINNCSTVQPMVAVERTVFYRERAAGMYSAMPYAISQV 1295

  Fly   593 SFEIPFQSLCTAMYIIISVHLTGNDATDSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLAVFL 657
            :.|:|        |::|..            :||.:::..|.....:|..||        ..||:
plant  1296 TCELP--------YVLIQT------------VYYSLIVYAMVGFEWKAEKFF--------WFVFV 1332

  Fly   658 GPILAVMFSVFGFCTRYIDITPLFRWMWHLSYFRAGFHGALNAIYGMDRPFLECPETAMYCHFRS 722
            .....:.::.:|..|  :.:||.   ....|.|.:.|:|..|...|...|..:.|:..::.::..
plant  1333 SYFSFLYWTYYGMMT--VSLTPN---QQVASIFASAFYGIFNLFSGFFIPRPKIPKWWIWYYWIC 1392

  Fly   723 PKVFLKYMMI 732
            |..:..|.:|
plant  1393 PVAWTVYGLI 1402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	90/239 (38%)
		3a01204	123..765	CDD:273361	156/640 (24%)
		ABC2_membrane	497..698	CDD:279410	38/213 (18%)
PEN3	NP_176196.1	PLN03140	31..1469	CDD:215599	162/660 (25%)
		ABC_trans_N	89..165	CDD:291196
		ABCG_PDR_domain1	154..426	CDD:213200
		ABC2_membrane	527..733	CDD:279410
		PDR_assoc	740..800	CDD:285559
		ABCG_PDR_domain2	864..1102	CDD:213199	90/239 (38%)
		ABC2_membrane	1197..1404	CDD:279410	45/242 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910