DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and ABCG24

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_175745.4	Gene:	ABCG24 / 841775	AraportID:	AT1G53390	Length:	1109	Species:	Arabidopsis thaliana

Alignment Length:	719	Identity:	169/719 - (23%)
Similarity:	287/719 - (39%)	Gaps:	167/719 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KASDAACCVGGANSDASSSSGVCSLKGHHGDPDSGCLGINCCTTAASSELSIDETSS-----TSS 67
            :|.|.:.|...|:|.|:.||.........|......|||........:...|.:|.|     ...
plant   406 EAIDMSTCSSPASSSAAQSSYENEDHAAAGSNGRASLGIEGKRVKGQTLAKIKKTQSQIFKYAYD 470

  Fly    68 RGSCELTSKVTNDLNGF-----QSPNYHQAVAHANFDHCDPVDIQFADVRYTVKKFSFPERKFVT 127
            |...|...:..|....|     .:.|......|.       :::.|.|:..|:|...
plant   471 RIEKEKAMEQENKNLTFSGIVKMATNSETRKRHL-------MELSFKDLTLTLKSNG-------- 520

  Fly   128 KEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSG---FCSTGVSGDIRVNRKPMAPSSERFRQ 189
            |::|..:.||.:.|.:||:||||||||::||:.::|   .|.  :||.|.:|.|  ..|...:::
plant   521 KQVLRCVTGSMKPGRITAVMGPSGAGKTSLLSALAGKAVGCK--LSGLILINGK--QESIHSYKK 581

  Fly   190 MLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGLDHRYNVPTGK---- 250
            ::.::.|||::...|.|.|.:...|..:|...::||.|:.:::.|:..|||....:...|.
plant   582 IIGFVPQDDVVHGNLTVEENLWFHAKCRLPADLSKADKVLVVERIIDSLGLQAVRSSLVGTVEKR 646

  Fly   251 -LSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQPSALI 314
             :||||:||:.:.||::..|.||:|||||:||||:|....:..|:..|.:|..|...:||||..:
plant   647 GISGGQRKRVNVGLEMVMEPSVLFLDEPTSGLDSASSQLLLRALRHEALEGVNICMVVHQPSYTL 711

  Fly   315 FEMFDKLYTVVDGH-CMYQGPVRELVPFLADQQLVCPSYHNPADYLLEVAVGEHQRDLNELIHAA 378
            |:.|:.|..:..|. .:|.|.|.::..:.:...:..|...||.||.::|
plant   712 FKTFNDLVLLAKGGLTVYHGSVNKVEEYFSGLGIHVPDRINPPDYYIDV---------------- 760

  Fly   379 NKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQFSSFDYVKPSPQELAL 443
                                  :|.:..:||.                  |...| |..||...|
plant   761 ----------------------LEGVVISMGN------------------SGIGY-KELPQRWML 784

  Fly   444 E-------EIKALSGGPESADPDL-------------------LEKNLRPQPQPLAKAGELARPP 482
            .       :::..|......:|||                   ::.|.|.:...:......:|..
plant   785 HKGYSVPLDMRNNSAAGLETNPDLGTNSPDNAEQTFARELWRDVKSNFRLRRDKIRHNFLKSRDL 849

  Fly   483 NAIRSASFLMQYVLLMQRILICAKR----------NYFLLLARIFSHIFIGVVFGYLYMNVGNNA 537
            :..|:.|..:||...:.||   ||:          :|.:||       ..|...|.| :...:.:
plant   850 SHRRTPSTWLQYKYFLGRI---AKQRMREAQLQATDYLILL-------LAGACLGSL-IKASDES 903

  Fly   538 QSVLGNYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLG----PYFLSLISFEIPF 598
            ....| |:|...:..||.   |:|.:.:|.|:     :.|:.|....|    ..||:..:.:| |
plant   904 FGAPG-YIYTIIAVSLLC---KIAALRSFSLD-----KLHYWRESASGMSSSACFLAKDTIDI-F 958

  Fly   599 QSLCTAMYIIISVHLTGNDATDSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLAVFLGPILAV 663
            ..|...: :.:|:.....:...:|...|.:|:.::..::..|:.          ||:||.|..|.
plant   959 NILVKPL-VYLSMFYFFTNPRSTFFDNYIVLVCLVYCVTGIAYA----------LAIFLQPSTAQ 1012

  Fly   664 MFSV 667
            :|||
plant  1013 LFSV 1016

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	79/238 (33%)
		3a01204	123..765	CDD:273361	144/594 (24%)
		ABC2_membrane	497..698	CDD:279410	41/185 (22%)
ABCG24	NP_175745.4	EcfA2	504..736	CDD:224047	81/250 (32%)
		ABCG_EPDR	505..731	CDD:213180	79/237 (33%)
		ABC2_membrane	867..>1006	CDD:304374	34/170 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820