DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and ABCG14

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_564383.1	Gene:	ABCG14 / 840064	AraportID:	AT1G31770	Length:	648	Species:	Arabidopsis thaliana

Alignment Length:	731	Identity:	192/731 - (26%)
Similarity:	324/731 - (44%)	Gaps:	129/731 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 IDETSSTSSRGSCELTSKVTNDLNGFQSPNYHQAVAHANFDHCDPVDIQFADVRYTVK----KFS 119
            :.:|.|.|......:||:     .|.|...|             |:.::|.:|.|.||    ...
plant    24 MSDTQSKSVLAFPTITSQ-----PGLQMSMY-------------PITLKFEEVVYKVKIEQTSQC 70

  Fly   120 FPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCSTGVSGDIRVNRKPMAPSS 184
            ....|...|.||:|:.|....||..|::||||:||:|||:.:.|..|...||.:..|.:|.   |
plant    71 MGSWKSKEKTILNGITGMVCPGEFLAMLGPSGSGKTTLLSALGGRLSKTFSGKVMYNGQPF---S 132

  Fly   185 ERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGLDHRYNVPTG 249
            ...::...::.|||:|.|.|.|.|.:...|.|:|...:|:..|.:.:..:::.|||:...|...|
plant   133 GCIKRRTGFVAQDDVLYPHLTVWETLFFTALLRLPSSLTRDEKAEHVDRVIAELGLNRCTNSMIG 197

  Fly   250 -----KLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQ 309
                 .:|||:|||::|..|::.||.:|.|||||:||||::....|..:|:|||.|.|:|.||||
plant   198 GPLFRGISGGEKKRVSIGQEMLINPSLLLLDEPTSGLDSTTAHRIVTTIKRLASGGRTVVTTIHQ 262

  Fly   310 PSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEVAVG---EHQRDL 371
            ||:.|:.||||:..:.:|..:|.|.....|.:.:..........||||.||::|.|   :.|::.
plant   263 PSSRIYHMFDKVVLLSEGSPIYYGAASSAVEYFSSLGFSTSLTVNPADLLLDLANGIPPDTQKET 327

  Fly   372 NELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQFSSFDYVKP 436
            :|......|:                 .||.:.::|:       :::..|....|:..|::|.|.
plant   328 SEQEQKTVKE-----------------TLVSAYEKNI-------STKLKAELCNAESHSYEYTKA 368

  Fly   437 SPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELARPPNAIRSASFLMQYVLLMQRI 501
            :.:.|..|:                                        ...::..|:.:|:||.
plant   369 AAKNLKSEQ----------------------------------------WCTTWWYQFTVLLQRG 393

  Fly   502 LICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLGNYVYLYGSTLLL----VYTGKMAV 562
            :...:...|..| |||..|.:..:.|.|:.:...:         ::...|.||    |:.|...:
plant   394 VRERRFESFNKL-RIFQVISVAFLGGLLWWHTPKS---------HIQDRTALLFFFSVFWGFYPL 448

  Fly   563 ---VLTFPLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQ-SLCTAMYIIISVHLTGNDATDSFR 623
               |.|||.|..||.:|..:..|:|..||::....::|.: :|.||...||  :..|....|...
plant   449 YNAVFTFPQEKRMLIKERSSGMYRLSSYFMARNVGDLPLELALPTAFVFII--YWMGGLKPDPTT 511

  Fly   624 IYYFMLLGIMASLSAQAWGFFVGATLPT-KLAVFLGPILAVMFSVFGFCTRYI-DITPLFRWMWH 686
            ....:|:.:.:.|.||..|...||.|.. |.|..|..:..::|.:.|  ..|: .|.|...|:.:
plant   512 FILSLLVVLYSVLVAQGLGLAFGALLMNIKQATTLASVTTLVFLIAG--GYYVQQIPPFIVWLKY 574

  Fly   687 LSYFRAGFHGALNAIYGMDRPFLECPETAMYCHFRS-PKVFLKYMMISDVHMSDCLILMGIVIGV 750
            |||....:...|...| .|..:.||.: .::|.... |.:  |.|.::::.:.  :.:||:::..
plant   575 LSYSYYCYKLLLGIQY-TDDDYYECSK-GVWCRVGDFPAI--KSMGLNNLWID--VFVMGVMLVG 633

  Fly   751 MHVLTLITLWHKLNKR 766
            ..::..:.| |::..|
plant   634 YRLMAYMAL-HRVKLR 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	90/238 (38%)
		3a01204	123..765	CDD:273361	177/660 (27%)
		ABC2_membrane	497..698	CDD:279410	56/210 (27%)
ABCG14	NP_564383.1	PLN03211	10..646	CDD:215634	191/727 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820