DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and ABCG35

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_172973.1	Gene:	ABCG35 / 838087	AraportID:	AT1G15210	Length:	1442	Species:	Arabidopsis thaliana

Alignment Length:	636	Identity:	163/636 - (25%)
Similarity:	270/636 - (42%)	Gaps:	144/636 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 PVDIQFADVRYTVKKFSFPERKFVTK---EILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGF 164
            |:.:.|.||:|.|...:....:.|.:   ::|.|:..:||.|.|||:||.|||||:||::|::|.
plant   837 PLAMSFDDVKYFVDMPAEMREQGVQETRLQLLKGVTSAFRPGVLTALMGVSGAGKTTLMDVLAGR 901

  Fly   165 CSTG-VSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKM 228
            .:.| :.||:||:..|  ...|.|.::..|..|.|:..||:.|.|.::.:|.|:|..:|:|..|:
plant   902 KTGGYIEGDVRVSGFP--KKQETFARISGYCEQTDIHSPQVTVRESLIFSAFLRLAKEVSKEDKL 964

  Fly   229 DLIKHILSLLGL----DHRYNVP--TGKLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCS 287
            ..:..::.|:.|    |....:|  || ||..|:|||.||:||::||.::::||||:|||:.:.:
plant   965 MFVDQVMELVELVDLRDAIVGLPGVTG-LSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAA 1028

  Fly   288 SCVALLKKLASQGHTIVCTIHQPSALIFEMFDKLYTVV-DGHCMYQGPV----RELVPFLADQQL 347
            ..:..::.....|.|:||||||||..|||.||:|..:. .||.:|.||:    .::|.:......
plant  1029 IVMRAVRNTVDTGRTVVCTIHQPSIDIFEAFDELLLMKRGGHVIYSGPLGRNSHKVVEYFESFPG 1093

  Fly   348 V--CPSYHNPADYLLEVAVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGG 410
            |  .|..:|||.::||                               :|...|.|
plant  1094 VPKIPEKYNPATWMLE-------------------------------ASSLAAEL---------- 1117

  Fly   411 KAVVKTSEALAAFAAAQFSSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKA 475
            |..|..:|...|.|..|.:                 |||                         .
plant  1118 KLGVDFAELYKASALCQRN-----------------KAL-------------------------V 1140

  Fly   476 GELARPPNAIRSASFLMQYVL-LMQRILICAKRNYFLL-------LARIFSHIFIGVVFGYLYMN 532
            .||:.||.......|..|:.. ...:...|..:.::..       |.|....:...::.|.::..
plant  1141 QELSVPPQGATDLYFATQFSQNTWGQFKSCLWKQWWTYWRSPDYNLVRFIFTLATSLMIGSVFWQ 1205

  Fly   533 VG---NNAQSVLGNYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLISF 594
            :|   :|.|.:......:|.:.:.:.......|.....:|..:..||.....|...||.:|.::.
plant  1206 IGGKRSNVQDLTMVIGAIYAAVVFVGINNCSTVQPMVAVERTVFYREKAAGMYSAIPYAISQVTC 1270

  Fly   595 EIPFQSLCTAMYIIISVHLTGNDATDS----------FRIYYFMLLGIM----------ASLSAQ 639
            |:|:..:.|..|.:|...:.|.:...|          |...|:...|:|          ||:.|.
plant  1271 ELPYVLIQTTYYSLIIYSMVGFEWKASKFLWFIFINYFSFLYWTYYGMMTVSLTPNQQVASIFAS 1335

  Fly   640 AW--------GFFVGATLPTKLAVFLGPILAVMFSVFGFCT-RYIDI-TPL 680
            |:        |||:......|..|:...|..|.::::|..| :|.|: ||:
plant  1336 AFYGIFNLFSGFFIPRPKIPKWWVWYYWICPVAWTIYGLITSQYGDVETPI 1386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	91/240 (38%)
		3a01204	123..765	CDD:273361	157/616 (25%)
		ABC2_membrane	497..698	CDD:279410	44/224 (20%)
ABCG35	NP_172973.1	PLN03140	8..1442	CDD:215599	163/636 (26%)
		ABC_trans_N	88..163	CDD:291196
		ABCG_PDR_domain1	182..424	CDD:213200
		ABC2_membrane	525..731	CDD:279410
		PDR_assoc	738..802	CDD:285559
		ABCG_PDR_domain2	837..1075	CDD:213199	91/240 (38%)
		ABC2_membrane	1170..1375	CDD:279410	39/204 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910