DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and ABCG6

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_196862.1	Gene:	ABCG6 / 831202	AraportID:	AT5G13580	Length:	727	Species:	Arabidopsis thaliana

Alignment Length:	768	Identity:	185/768 - (24%)
Similarity:	326/768 - (42%)	Gaps:	177/768 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 TTAASSELSIDETSSTSSRGSCELTSKVTNDLNGFQSPNYHQAVAHANFDHCDPVDIQFADVRYT 114
            ||.|....::|:::..|..                   .:|..|..|:.|...|..:.|.|:.|:
plant    31 TTFAQLLQNVDDSTRRSHH-------------------QHHVDVDLASPDQSVPFVLSFTDLTYS 76

  Fly   115 VK---KFSFPERKFV---------------TKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVM 161
            ||   ||::  |:.|               ||.:|:|:.|..|.||:.|::|.||:|||||::.:
plant    77 VKVRRKFTW--RRSVSSDPGAPSEGIFSSKTKTLLNGITGEARDGEILAVLGASGSGKSTLIDAL 139

  Fly   162 SGFCSTG-VSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKA 225
            :...:.| :.|::.:|.:.:  :|:..:.:..|:.|||||.|.|.|.|.::.||..:|...::|:
plant   140 ANRIAKGSLKGNVTLNGEVL--NSKMQKAISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSLSKS 202

  Fly   226 YKMDLIKHILSLLGLDHRYNVPTGK-----LSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSS 285
            .|...::.::..|||.:..|...|.     :|||:::|::|.:::|.:|.:|:|||||:||||:|
plant   203 KKSLRVQALIDQLGLRNAANTVIGDEGHRGISGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTS 267

  Fly   286 CSSCVALLKKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCP 350
            ..|.:.:||::|..|..::.|:||||..:..:.|:|..:..|..::.|....|..|.|:.....|
plant   268 ALSVIKVLKRIAQSGSMVIMTLHQPSYRLLRLLDRLLFLSRGQTVFSGSPAMLPRFFAEFGHPIP 332

  Fly   351 SYHNPADYLLEVAVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVK 415
            .:.|..::.|:                                      |:..::.:.||
plant   333 EHENRTEFALD--------------------------------------LIRELEGSAGG----- 354

  Fly   416 TSEALAAFAAAQFSSFDYVKPSPQE---LALEEI--------KALSGGPESADPDLLEKNLRPQP 469
             :.:|..|.    ..|...|..|:.   |:|:|.        |.:||...:....        ..
plant   355 -TRSLVEFN----KGFRQRKAEPRSQTGLSLKEAISASISKGKLVSGATTTTHSS--------GS 406

  Fly   470 QPLAKAGELARPPNAIRSASFLMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVG 534
            .|::.....|.|        |.::..:|.:|.:..::|...|...|:.:.:..|.:...::..:.
plant   407 SPVSTIPTFANP--------FWVELAVLAKRSMTNSRRQPELFGIRLGAVLVTGFILATMFWQLD 463

  Fly   535 NNAQSV---LGNYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLISFEI 596
            |:.:.|   ||.:.:...:|.   ||...|:.: |..|..:..||.....|:...|.||.....:
plant   464 NSPKGVQERLGCFAFAMSTTF---YTCADALPV-FLQERFIFMRETAYNAYRRSSYVLSHSLVAL 524

  Fly   597 PFQSLCTAMYIIISVHLTGNDATDSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLA-----VF 656
            |...:.:..:..|:....|.|......::||::  |:||       |:.|::..|.|:     |.
plant   525 PSLIILSLAFAAITFWGVGLDGGLMGFLFYFLV--ILAS-------FWAGSSFVTFLSGVVPHVM 580

  Fly   657 LG-----PILA--VMFSVFGFCTRYIDITPLFRWMWHLSYFRAGFHGALNAIYGMDRPFLECPET 714
            ||     .|||  ::||.| |..|  |..|.: |:|        ||......|    |:    |.
plant   581 LGYTIVVAILAYFLLFSGF-FINR--DRIPGY-WIW--------FHYISLVKY----PY----EA 625

  Fly   715 AMYCHFRSP-KVFLKYMMISDVHMSDCLILMGIVIGVMHVLTLITLWHKLNKR 766
            .:...|..| |.|::     .|.:.|...|:.:..| |.|..|.|:...|..|
plant   626 VLLNEFGDPTKCFVR-----GVQIFDNTPLVAVPQG-MKVRLLATMSKSLGMR 672

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	82/253 (32%)
		3a01204	123..765	CDD:273361	167/689 (24%)
		ABC2_membrane	497..698	CDD:279410	52/215 (24%)
ABCG6	NP_196862.1	3a01204	105..726	CDD:273361	166/673 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920