DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and ABCG18

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_191071.1	Gene:	ABCG18 / 824677	AraportID:	AT3G55110	Length:	708	Species:	Arabidopsis thaliana

Alignment Length:	736	Identity:	188/736 - (25%)
Similarity:	315/736 - (42%)	Gaps:	131/736 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LSIDETSSTSSRGSCELTSKVTNDLN-----GFQSPNYH-QAVAHANFDHCDPVDIQFADVRYTV 115
            |.|..|....|....||. |..||..     |..:|..| ..:|.|......|..:.|.::.|.|
plant     9 LDISHTGGNESPTLGELL-KDFNDSGRKKYPGENAPTQHILDLAPAAETRSVPFLLSFNNLSYNV 72

  Fly   116 ---KKFSFPERKFVT-KEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSG-FCSTGVSGDIRV 175
               ::|.|..||..: |.:|..:.|..|.||:.|::|.||||||||::.::| .....:.|.:.:
plant    73 VLRRRFDFSRRKTASVKTLLDDITGEARDGEILAVLGGSGAGKSTLIDALAGRVAEDSLKGTVTL 137

  Fly   176 NRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGL 240
            |.:.:. .|...:.:..|:.|||||.|.|.|.|.::.|:..:|...:.|:.||:.::.::..|||
plant   138 NGEKVL-QSRLLKVISAYVMQDDLLFPMLTVKETLMFASEFRLPRSLPKSKKMERVETLIDQLGL 201

  Fly   241 DHRYNVPTGK-----LSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQG 300
            .:..:...|.     :|||:::|::|.:::|.:|.:|:|||||:||||::....|.:||::|..|
plant   202 RNAADTVIGDEGHRGVSGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTNAFMVVQVLKRIAQSG 266

  Fly   301 HTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEV--- 362
            ..::.:||||||.|..:.|:|..:..|..::.|....|..|.:......|...|..::.|:|
plant   267 SVVIMSIHQPSARIIGLLDRLIILSHGKSVFNGSPVSLPSFFSSFGRPIPEKENITEFALDVIRE 331

  Fly   363 --AVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAA 425
              ...|..|||.|.    |:|:                      ::|...:|..::..:|....|
plant   332 LEGSSEGTRDLVEF----NEKW----------------------QQNQTARATTQSRVSLKEAIA 370

  Fly   426 AQFSSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELARPPNAIRSASF 490
            |..|.                ..|..|...|:|..:|           .....|.||
plant   371 ASVSR----------------GKLVSGSSGANPISME-----------TVSSYANPP-------- 400

  Fly   491 LMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGN---NAQSVLGNYVYLYG-ST 551
            |.:..:|.:|.:....|...|:..||.:.:..|::...:|..:.|   .||..:|  .:.:| ||
plant   401 LAETFILAKRYIKNWIRTPELIGMRIGTVMVTGLLLATVYWRLDNTPRGAQERMG--FFAFGMST 463

  Fly   552 LLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLS--LISF-EIPFQSLCTAMYIIISVHL 613
            :.......:.|   |..|..:..||..:..|:...|.:|  |:|. ::...|:..|.....:|.|
plant   464 MFYCCADNIPV---FIQERYIFLRETTHNAYRTSSYVISHALVSLPQLLALSIAFAATTFWTVGL 525

  Fly   614 TGNDATDSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLAVFLGPILAVMFSVF--GFCTRYI- 675
            :|  ..:||  :|:.|:...|..|..:...|:...:|..:..::..|..:.:.:.  ||   ||
plant   526 SG--GLESF--FYYCLIIYAAFWSGSSIVTFISGLIPNVMMSYMVTIAYLSYCLLLGGF---YIN 583

  Fly   676 -DITPLFRWMWHLSYFRAGFHGALNAIYGMDRPFLECPETAMYCHFRSP-KVFLKYMMISDVHMS 738
             |..||: |:|        ||    .|..:..|:    |..:...|..| :.|:|.:.:.|.
plant   584 RDRIPLY-WIW--------FH----YISLLKYPY----EAVLINEFDDPSRCFVKGVQVFDG--- 628

  Fly   739 DCLILMGIVIGVMHVLTLITL 759
               .|:..|..||.|..|.||
plant   629 ---TLLAEVSHVMKVKLLDTL 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	79/239 (33%)
		3a01204	123..765	CDD:273361	168/661 (25%)
		ABC2_membrane	497..698	CDD:279410	50/211 (24%)
ABCG18	NP_191071.1	3a01204	57..707	CDD:273361	174/687 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920