DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17646 and ABCG20

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_190919.1	Gene:	ABCG20 / 824519	AraportID:	AT3G53510	Length:	739	Species:	Arabidopsis thaliana

Alignment Length:	781	Identity:	184/781 - (23%)
Similarity:	329/781 - (42%)	Gaps:	180/781 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 TAASSELSIDETSSTSSRGSCELTSKVTNDLNGFQSPNYHQAVAHANFDHCDPVDIQFADVRYTV 115
            |.|...:|:::.....||.           ::...:.|:..:|..:......|..:.|.|:.|:|
plant    44 TLAELLMSVEDEGDDQSRA-----------MDIAVASNFWSSVPSSRVPSSSPFVLSFKDLTYSV 97

  Fly   116 ---KKFS-FP----------ERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCS 166
               |||. ||          :.:..||.:|:|::|..|.||:.|::|.||:|||||::.::...|
plant    98 KIKKKFKPFPCCGNSPFDGNDMEMNTKVLLNGISGEAREGEMMAVLGASGSGKSTLIDALANRIS 162

  Fly   167 -TGVSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDL 230
             ..:.|||.:|.:.:  .|...:.:..|:.|||||.|.|.|.|.::.:|..:|...::|..|...
plant   163 KESLRGDITLNGEVL--ESSLHKVISAYVMQDDLLFPMLTVEETLMFSAEFRLPSSLSKKKKKAR 225

  Fly   231 IKHILSLLGLDHRYNVPTGK-----LSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCV 290
            ::.::..|||.:......|.     :|||:::|::|..::|.:|.:|:|||||:||||:|....|
plant   226 VQALIDQLGLRNAAKTVIGDEGHRGVSGGERRRVSIGTDIIHDPIILFLDEPTSGLDSTSAYMVV 290

  Fly   291 ALLKKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNP 355
            .:|:::|..|..::.:|||||..|..:.|||..:..|:.:|.|....|..|.::.....|...|.
plant   291 KVLQRIAQSGSIVIMSIHQPSYRILGLLDKLIFLSRGNTVYSGSPTHLPQFFSEFGHPIPENENK 355

  Fly   356 ADYLLEVAVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEAL 420
            .::.|::        :.||         ||       |.:....|||..|:
plant   356 PEFALDL--------IREL---------ED-------SPEGTKSLVEFHKQ-------------- 382

  Fly   421 AAFAAAQFSS----------FDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKA 475
              :.|.|.||          .|.:..|     :...|.:||.          .|||...|..|.
plant   383 --WRAKQTSSQSRRNTNVSLKDAISAS-----ISRGKLVSGA----------TNLRSSFQTFAN- 429

  Fly   476 GELARPPNAIRSASFLMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSV 540
                         .|..:.:::.:|.::.::|...|...|:.:.:..|::...::..:.|:.:.:
plant   430 -------------PFWTEMLVIGKRSILNSRRQPELFGIRLGAVLVTGMILATIFWKLDNSPRGI 481

  Fly   541 ---LGNYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQSLC 602
               ||.:.:...:|.   ||...|:.: |..|..:..||.....|:...|.|:.....||...:.
plant   482 QERLGFFAFAMSTTF---YTCAEAIPV-FLQERYIFMRETAYNAYRRSSYVLAHTIISIPALIIL 542

  Fly   603 TAMY---IIISVHLTGNDATDSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLA-----VFLG- 658
            :|.:   ...:|.|.|  .::.|..::|.:|          ..|:.|::..|.|:     |.:|
plant   543 SAAFAASTFSAVGLAG--GSEGFLFFFFTIL----------TAFWAGSSFVTFLSGVVSHVMIGF 595

  Fly   659 ----PILA--VMFSVFGFCTRYIDITPLFRWMW--HLSYFRAGFHGALNAIYGMDRPFLECPETA 715
                .|||  ::||.| |.:|  |..||: |:|  :||..:..:.|.|...:          |..
plant   596 TVVVAILAYFLLFSGF-FISR--DRIPLY-WIWFHYLSLVKYPYEGVLQNEF----------EDP 646

  Fly   716 MYCHFRSPKVF-----------LKYMMISDVH-------MSDCLILMGIVIGVMHVLTLITLWHK 762
            ..|..|..::|           :|..::..:.       .::..:..||.|.....:|.|:.|:.
plant   647 TKCFVRGIQMFDNSPLGQVPTAVKISLLKSMSGVLGINVTAETCVTTGIDILKQQGITEISKWNC 711

  Fly   763 L 763
            |
plant   712 L 712

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	84/249 (34%)
		3a01204	123..765	CDD:273361	167/695 (24%)
		ABC2_membrane	497..698	CDD:279410	50/220 (23%)
ABCG20	NP_190919.1	P-loop_NTPase	119..333	CDD:304359	74/215 (34%)
		3a01204	120..738	CDD:273361	167/694 (24%)
		ABC2_membrane	438..641	CDD:279410	51/222 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920