DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and ABCG21

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_001189973.1	Gene:	ABCG21 / 822149	AraportID:	AT3G25620	Length:	672	Species:	Arabidopsis thaliana

Alignment Length:	758	Identity:	192/758 - (25%)
Similarity:	343/758 - (45%)	Gaps:	150/758 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 ELSIDETSSTSSRGSCELTSKVTNDLNGFQSPNYHQAVAHANFDH----------------CDPV 104
            |.|..:|.|.:...    ||.|..  |.|.||::.......:.||                ..|:
plant     8 ESSFPKTPSANRHE----TSPVQE--NRFSSPSHVNPCLDDDNDHDGPSHQSRQSSVLRQSLRPI 66

  Fly   105 DIQFADVRYTVKK--------FSFPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVM 161
            .::|.::.|::|.        |...|.| ..:.:|..::|..:.|||.|::||||:||:||:..:
plant    67 ILKFEELTYSIKSQTGKGSYWFGSQEPK-PNRLVLKCVSGIVKPGELLAMLGPSGSGKTTLVTAL 130

  Fly   162 SGFCSTGVSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAY 226
            :|.....:||.:..|.:|...|.:|   ...::.|||:|.|.|.|.|.:...|.|:|..::|:..
plant   131 AGRLQGKLSGTVSYNGEPFTSSVKR---KTGFVTQDDVLYPHLTVMETLTYTALLRLPKELTRKE 192

  Fly   227 KMDLIKHILSLLGLDHRYNVPTG-----KLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSC 286
            |::.::.::|.|||....|...|     .:|||::||::|..|::.||.:|.|||||:||||::.
plant   193 KLEQVEMVVSDLGLTRCCNSVIGGGLIRGISGGERKRVSIGQEMLVNPSLLLLDEPTSGLDSTTA 257

  Fly   287 SSCVALLKKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGP---VRELVPFLADQQLV 348
            :..||.|:.||..|.|:|.||||||:.::.||||:..:.:|..:|.|.   |.|....:..|
plant   258 ARIVATLRSLARGGRTVVTTIHQPSSRLYRMFDKVLVLSEGCPIYSGDSGRVMEYFGSIGYQ--- 319

  Fly   349 CP--SYHNPADYLLEVAVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVE--SIKENMG 409
             |  |:.||||::|::|.|          ..::.|.|:.::     ::..:.||.|  |:|:::
plant   320 -PGSSFVNPADFVLDLANG----------ITSDTKQYDQIE-----TNGRLDRLEEQNSVKQSL- 367

  Fly   410 GKAVVKTSEALAAFAAAQFSSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLR--PQPQPL 472
                                                   :|...::..|.|.|:..|  ||.|..
plant   368 ---------------------------------------ISSYKKNLYPPLKEEVSRTFPQDQTN 393

  Fly   473 AKAGELA---RPPNAIRSASFLMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVG 534
            |:..:.|   |.|     .|:.||:.:|::|.|.......|..| |||..:.:.::.|.|:.:
plant   394 ARLRKKAITNRWP-----TSWWMQFSVLLKRGLKERSHESFSGL-RIFMVMSVSLLSGLLWWH-- 450

  Fly   535 NNAQSVLGNYVYLYGSTLLL----VYTGKMAV---VLTFPLEIDMLTREHFNRWYKLGPYFLSLI 592
                   ....:|.....||    ::.|...:   :.|||.|..||.:|..:..|:|..|:::..
plant   451 -------SRVAHLQDQVGLLFFFSIFWGFFPLFNAIFTFPQERPMLIKERSSGIYRLSSYYIART 508

  Fly   593 SFEIPFQSLCTAMYIIISVHLTGNDATDSFRIYYFMLLGIMAS-LSAQAWGFFVGATL-PTKLAV 655
            ..::|.:.:...:::.|:..:.|  ...|...:...|:.::.: |.||..|..:||.| ..|.|.
plant   509 VGDLPMELILPTIFVTITYWMGG--LKPSLTTFIMTLMIVLYNVLVAQGVGLALGAILMDAKKAA 571

  Fly   656 FLGPILAVMFSVFGFCTRYIDITPLF-RWMWHLSYFRAGFHGALNAIYGMDRPFLECPETAMYCH 719
            .|..:|.::|.:.|  ..||...|.| .|:.::|:....:...:...|..|..: || .:.::|.
plant   572 TLSSVLMLVFLLAG--GYYIQHIPGFIAWLKYVSFSHYCYKLLVGVQYTWDEVY-EC-GSGLHCS 632

  Fly   720 FRSPKVFLKYMMISDVHMSDCL---ILMGIVIGVMHVLTLITL 759
                  .:.|..|.::.:.:.:   :.:.:::.:..||..:.|
plant   633 ------VMDYEGIKNLRIGNMMWDVLALAVMLLLYRVLAYLAL 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	86/242 (36%)
		3a01204	123..765	CDD:273361	173/667 (26%)
		ABC2_membrane	497..698	CDD:279410	48/210 (23%)
ABCG21	NP_001189973.1	PLN03211	43..670	CDD:215634	181/717 (25%)
		P-loop_NTPase	89..304	CDD:304359	81/218 (37%)
		ABC2_membrane	416..615	CDD:279410	48/212 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820