DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17646 and ABCG1

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_181467.1	Gene:	ABCG1 / 818520	AraportID:	AT2G39350	Length:	740	Species:	Arabidopsis thaliana

Alignment Length:	794	Identity:	182/794 - (22%)
Similarity:	313/794 - (39%)	Gaps:	204/794 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 SSELSIDETSSTSSRGS-CELTSKVTNDLNGFQSPNYHQAVAHANFDHCD------PVDIQFADV 111
            |.||:...:...|:.|. .:..|.|.....|.::| .|:::   |.|:.|      |..:.|.::
plant    12 SMELNTISSIHDSTLGQLLKNVSDVRKMAIGDETP-VHESL---NQDYNDGYMRTVPFVLSFDNL 72

  Fly   112 RYTVK-------KFSFPERKF-----------VTKEILHGLNGSFRSGELTAIMGPSGAGKSTLL 158
            .|.|.       :..||.|:.           .||.:|:.::|..|.||:.|::|.||:|||||:
plant    73 TYNVSVRPKLDFRNLFPRRRTEDPEIAQTARPKTKTLLNNISGETRDGEIMAVLGASGSGKSTLI 137

  Fly   159 NVMSGFCSTG-VSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKV 222
            :.::...:.| :.|.:::|.:.:  .|...:.:..|:.|||||.|.|.|.|.::.||..:|...:
plant   138 DALANRIAKGSLKGTVKLNGETL--QSRMLKVISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSL 200

  Fly   223 TKAYKMDLIKHILSLLGLDHRYNVPTGK-----LSGGQKKRLAIALELISNPPVLYLDEPTTGLD 282
            .|:.|...::.::..||:.:......|.     :|||:::|::|.:::|.:|.:|:|||||:|||
plant   201 PKSKKKLRVQALIDQLGIRNAAKTIIGDEGHRGISGGERRRVSIGIDIIHDPILLFLDEPTSGLD 265

  Fly   283 SSSCSSCVALLKKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQL 347
            |:|....|.:||::|..|..::.:|||||..:..:.|:|..:..||.:|.|....|..|..:...
plant   266 STSAFMVVKVLKRIAQSGSIVIMSIHQPSHRVLGLLDRLIFLSRGHTVYSGSPASLPRFFTEFGS 330

  Fly   348 VCPSYHNPADYLLEVAVGEHQRDLNELIHAA---------NKKYYE------------------- 384
            ..|...|..::.|::        :.||..:|         |||:.|
plant   331 PIPENENRTEFALDL--------IRELEGSAGGTRGLIEFNKKWQEMKKQSNRQPPLTPPSSPYP 387

  Fly   385 ----------DVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQFSSFDYVKPSPQ 439
                      .:.|.:.:|..      ||:..  ||.....|:.|:.|||            :|.
plant   388 NLTLKEAIAASISRGKLVSGG------ESVAH--GGATTNTTTLAVPAFA------------NPM 432

  Fly   440 ELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELARPPNAIRSASFLMQYVLLMQRILIC 504
            .:   |||.||                                                :|.::.
plant   433 WI---EIKTLS------------------------------------------------KRSMLN 446

  Fly   505 AKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSV---LGNYVYLYGSTLLLVYTGKMAVVLTF 566
            ::|...|...||.|.:..|.:...::..:.|:.:.|   ||.:.:.. ||:.......:.|.|.
plant   447 SRRQPELFGIRIASVVITGFILATVFWRLDNSPKGVQERLGFFAFAM-STMFYTCADALPVFLQ- 509

  Fly   567 PLEIDMLTREHFNRWYKLGPYFLS--LISF-EIPFQSLCTAMYIIISVHLTGNDATDSFRIYYFM 628
              |..:..||.....|:...|.||  ::|| .:.|.|:..|.....:|.|.|     ......|.
plant   510 --ERYIFMRETAYNAYRRSSYVLSHAIVSFPSLIFLSVAFAATTYWAVGLDG-----GLTGLLFY 567

  Fly   629 LLGIMASL-SAQAWGFFVGATLPTKLAVFLG-----PILAVMFSVFGFCTRYIDITPLFRWMWHL 687
            .|.|:||. |..::..|:...:|   :|.||     .|||......||......|...:.|..::
plant   568 CLIILASFWSGSSFVTFLSGVVP---SVMLGYTIVVAILAYFLLFSGFFINRNRIPDYWIWFHYM 629

  Fly   688 SYFRAGFHGALNAIYGMDRPFLECPETAMYCHFRSPKVF-----------LKYMMISDVHMSDCL 741
            |..:..:...|...:          ..|..|..|..::|           :|..::..|..|
plant   630 SLVKYPYEAVLQNEF----------SDATKCFVRGVQIFDNTPLGELPEVMKLKLLGTVSKS--- 681

  Fly   742 ILMGIVIGVMHVLT 755
              :|:.|.....||
plant   682 --LGVTISSTTCLT 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	78/253 (31%)
		3a01204	123..765	CDD:273361	163/711 (23%)
		ABC2_membrane	497..698	CDD:279410	49/212 (23%)
ABCG1	NP_181467.1	3a01204	106..739	CDD:273361	162/696 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920