DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and ABCG3

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_001318302.1	Gene:	ABCG3 / 817351	AraportID:	AT2G28070	Length:	730	Species:	Arabidopsis thaliana

Alignment Length:	813	Identity:	189/813 - (23%)
Similarity:	316/813 - (38%)	Gaps:	210/813 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DIKASDAACCVGGANS--DASSSSGVCSLKGHHGDPDSGCLGINCCTTAASSELSIDETSSTSSR 68
            |::..|.|   ||.:|  ||:                         ||..|..||...:.|.:|.
plant    58 DLRMEDEA---GGGDSINDAT-------------------------TTPVSPSLSKMNSGSMASP 94

  Fly    69 GSCELTSKVTNDLNGFQSPNYHQAVAHANFDHCDPVDIQFADVRYTVKKFSFPERKFVTKEILHG 133
            ...|          |.......:.:|.|:        |.:.|:..|:|    .:||:..| ::..
plant    95 PVPE----------GGAGTGVVRKIAGAS--------IAWKDLTVTMK----GKRKYSDK-VVKS 136

  Fly   134 LNGSFRSGELTAIMGPSGAGKSTLLNVMSGFC--STGVSGDIRVN--RKPMAPSSERFRQMLCYI 194
            .||....|.:|.||||:.:||||||..::|..  |..:.|::.||  :..|...|..|      :
plant   137 SNGYAFPGTMTVIMGPAKSGKSTLLRALAGRLPPSAKMYGEVFVNGSKSHMPYGSYGF------V 195

  Fly   195 HQDDLLRPQLLVGEIMLLAAHLKL-GFKVTK-------AYKMDLIKHILSLLGLDHRYNVPTGKL 251
            .::..|...|.|.|.:..:|.|:| ||...|       ...|.|..:...|:| .|.|   ...|
plant   196 ERETQLIGSLTVREFLYYSALLQLPGFLFQKRSVVEDAIQAMSLSDYANKLIG-GHCY---MKGL 256

  Fly   252 SGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQPSALIFE 316
            ..|:::|::||.||:..|.:|::|||...|||.|....:..||||||.|.|:|.||:|.|..:|.
plant   257 RSGERRRVSIARELVMRPHILFIDEPLYHLDSVSALLMMVTLKKLASMGCTLVFTIYQSSTEVFG 321

  Fly   317 MFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEVAVGEHQRDLNELIHAANKK 381
            :||::..:.:|:.::.|.....:...::....||...:|:|:.|...    ..|.:.:| |..|.
plant   322 LFDRICLLSNGNTLFFGETLACLQHFSNAGFPCPIMQSPSDHFLRAI----NTDFDRII-AMCKN 381

  Fly   382 YYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQFSSFDYVKPSPQELALEEI 446
            :.:|        :.|.:.:      ||.....::|.|       |.:.|
plant   382 WQDD--------NGDFSAV------NMDTAVAIRTLE-------ATYKS---------------- 409

  Fly   447 KALSGGPESADPDLLEKNL-------RPQPQPLAKAGELARPPNAIRSASFLMQYVLLMQRILIC 504
                    |||.|.:|..:       ..|.:...|||.      |.|.|....:.:|:|.|
plant   410 --------SADADSVEAMIIKLTEREGTQLKSKGKAGA------ATRVAVLTWRSLLVMSR---- 456

  Fly   505 AKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLGN----YVYLYGSTLLLVYTGKMAVVLT 565
             :..|:.|  |:..::.:.:..|.||..:|::..||...    :|::..::||     .:|.:.:
plant   457 -EWKYYWL--RLILYMILTLSIGTLYSGLGHSLSSVATRVAAVFVFVSFASLL-----GIAGIPS 513

  Fly   566 FPLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQSLCTAMYIIISVHLTGNDATDSFRIY----Y 626
            ...||.:...|..|:......:.|......|||..|.:....::...:.|.....|..:|    :
plant   514 LLKEIKIYRSEASNQHSGAFVFLLGQFLGSIPFLFLMSISSSLVFYFMVGLRDDFSLLMYFVLNF 578

  Fly   627 FMLL----GIMASLSAQAWGFFVGATLPTKLAVFLGPILAVMFSVFGFCTRYIDITPLFRWMWHL 687
            ||.|    |:|..: |..|.....:|| |.::|.    :.:|.:...|..|    |.|.:.:|..
plant   579 FMCLLVNEGLMLFI-ACIWRDVYWSTL-TLISVH----VIMMLAAGHFRIR----TALPKPVWTY 633

  Fly   688 SYFRAGFH-------------------GALNAIYGMDRPFLECPETAMYCHFR-SPKVFLKYMMI 732
            .:....||                   |.:.:|.|..         |:..::: ||....|:
plant   634 PFAYISFHTYSIEGLLENEYLGEVFAVGEVRSISGYQ---------AIQGNYQISPDTNAKW--- 686

  Fly   733 SDVHMSDCLILMGIVIGVMHVLTLITLWHKLNK 765
                 .:.|:|:.:..| ..:|..:.|...|||
plant   687 -----RNMLVLLAMAFG-YRLLVYVLLRFGLNK 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	78/241 (32%)
		3a01204	123..765	CDD:273361	164/692 (24%)
		ABC2_membrane	497..698	CDD:279410	47/231 (20%)
ABCG3	NP_001318302.1	3a01204	110..713	CDD:273361	170/721 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900