Protein Alignment CG17646 and abcg4b

DIOPT Version :9

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_001104682.1
• Gene: abcg4b / 794238
• ZFINID: ZDB-GENE-080215-10
• Length: 644
• Species: Danio rerio
• Alignment Length: 719
• Identity: 260/719 - (36%)
• Similarity: 377/719 - (52%)
• Gaps: 103/719 - (14%)

  Fly    65 TSSRGSCELTSKVTNDLNGFQSPNYHQAVAH-----------ANFDHC---DPVDIQFADVRYTV 115
            ||..||..:..: .:..||...|.....:.|           ..|.|.   ..|:::|.::.||:
Zfish     5 TSDPGSVSIGME-ESLCNGGSQPQEAPLLTHLKKVENHITEAQRFSHLPKRTTVELEFKELCYTI 68

  Fly   116 KKFSFPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCSTGVSGDIRVNRKPM 180
            ::..: .:|...|.:|..|:|.|.|.||..||||||||||||:|:::|:..||::|.|.||.|..
Zfish    69 REGPW-WKKQGYKALLKCLSGKFSSRELIGIMGPSGAGKSTLMNILAGYRETGMTGQILVNGKLR 132

  Fly   181 APSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGLDHRYN 245
            .|.:  ||:|.|||.|:|.|.|.|.|.|.|:::|:|||  ..:...|.:|||.||:.|||....:
Zfish   133 DPRT--FRKMSCYIMQEDKLLPHLSVQEAMMVSANLKL--NESSEVKKELIKEILTALGLHECVH 193

  Fly   246 VPTGKLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQP 310
            ..|..|||||.|||||||||::||||::.||||:||||:||...|:|:|.||..|.||:||||||
Zfish   194 TRTVSLSGGQCKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQP 258

  Fly   311 SALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEVAVGEHQRDLNELI 375
            ||.:||||||||.:..|.|:|:|.|..|:|:|....|.||:||||||:::|||.||: .|||.:
Zfish   259 SAKLFEMFDKLYILSQGQCIYKGSVPYLIPYLRGLGLHCPTYHNPADFIIEVASGEY-GDLNPV- 321

  Fly   376 HAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQFSSFDYVKPSPQE 440
                                    |.|:::..|
Zfish   322 ------------------------LFEAVQGGM-------------------------------- 330

  Fly   441 LALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELARPPNAIRSASF----LMQYVLLMQRI 501
            .||||                :.|...:....:.|.:..:.|..:.|.:|    |.|:.:|.:|.
Zfish   331 CALEE----------------KCNCIDKTTVTSCAAKCVKDPGHVESHTFATSSLTQFCILFKRT 379

  Fly   502 LICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLGNYVYLYGSTLLLVYTGKMAVVLTF 566
            .|...|:..|...|:.|||.|||:.|.||:|:||:|..|..|..:|:.|.|.|::...|..||||
Zfish   380 FITICRDQVLTHLRLMSHISIGVLIGLLYLNIGNDASKVFNNTGFLFFSMLFLMFGALMPTVLTF 444

  Fly   567 PLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQSLCTAMYIIISVHLTGNDATDSFRIYYFMLLG 631
            |||:.:..|||.|.||.|..|:|:....:||||.||..||..|...:| ....::.|...|:.|.
Zfish   445 PLEMAVFLREHLNYWYSLKAYYLAKTMADIPFQVLCPIMYCSIVYWMT-EQPPEASRYLLFLALS 508

  Fly   632 IMASLSAQAWGFFVG-ATLPTKLAVFLGPILAVMFSVF-GFCTRYIDITPLFRWMWHLSYFRAGF 694
            |..:|.||:.|..|| |:...::|.|:||:..:...:| ||...:..|....:|..::||.|.||
Zfish   509 ICTALVAQSLGLLVGAASTSLQVATFVGPVTGIPVLLFSGFFVNFDTIPEYLQWSSYVSYVRYGF 573

  Fly   695 HGALNAIYGMDRPFLECPETAMYCHFRSPKVFLKYMMISDVHMSDCLILMGIVIGVMHVLTLITL 759
            ...:.:||||:|...|||  ...|.|:.|:..|:.:.:.|..:....|::||...::.:.|.:.|
Zfish   574 EEVILSIYGMNRTERECP--GRVCKFQRPEEVLQLLDVEDAKLYMDFIVLGIFFVILRLATYVVL 636

  Fly   760 WHKL 763
            .:|:
Zfish   637 RYKI 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	118/229 (52%)
		3a01204	123..765	CDD:273361	246/647 (38%)
		ABC2_membrane	497..698	CDD:279410	77/202 (38%)
abcg4b	NP_001104682.1	3a01204	42..644	CDD:273361	252/681 (37%)
		ABCG_EPDR	57..281	CDD:213180	118/228 (52%)
		ABC2_membrane	375..574	CDD:279410	76/199 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.880