Protein Alignment CG17646 and abcg2a

DIOPT Version :9

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: XP_021325521.1
• Gene: abcg2a / 735312
• ZFINID: ZDB-GENE-050517-35
• Length: 644
• Species: Danio rerio
• Alignment Length: 615
• Identity: 167/615 - (27%)
• Similarity: 295/615 - (47%)
• Gaps: 91/615 - (14%)

  Fly   106 IQFADVRYTVK-KFSFPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCS-TG 168
            :.|.::.|::| |..|.:.|...|.||.||||..:.| |.||:|.:|:|||:.|:|::.... .|
Zfish    33 VSFHNINYSLKMKSGFCKSKSTKKNILIGLNGIMKPG-LNAILGATGSGKSSFLDVLAARKDPAG 96

  Fly   169 VSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKH 233
            :||::.::..|..|:   |:.:..|:.|||::...|.|.|.:..:|.|:|...:.:..|.:.::.
Zfish    97 LSGEVLIDGAPQPPN---FKCLSGYVVQDDVVMGTLTVRENLRFSAALRLPKSIKQREKDEKVER 158

  Fly   234 ILSLLGLDHRYNVPTGK-----LSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALL 293
            ::..|||....:...|.     :|||::||..|.:|||.:||||:|||||||||:|:.:|.:.||
Zfish   159 LIQELGLSKVADSRVGTQLIRGVSGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTANSVLMLL 223

  Fly   294 KKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADY 358
            ||:.:.|.||:.:||||...|:.:||.|..:|.|..:|.||.::.:.:.:.....|..::||||:
Zfish   224 KKMGNNGRTIILSIHQPRYSIYRLFDSLTLLVGGKLVYHGPAQDALSYFSQIGYTCEPHNNPADF 288

  Fly   359 LLEVAVGEHQRDLNELIHAANKKYYEDVDRHRYMSS----DDMARLVESIKENMGGKAVVKTSEA 419
            .|:|..|:..      ....||.|.|.||:.:..||    :|  ||||
Zfish   289 FLDVINGDSS------AVTLNKLYEEVVDQDQLSSSLKGIED--RLVE----------------- 328

  Fly   420 LAAFAAAQFSSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELARPPNA 484
                        :|.:.|..:....:::.:..|.        :.:.||:.:.:.
Zfish   329 ------------EYQRSSIFQQTHADLQRIVQGQ--------DYSTRPKSRTIT----------- 362

  Fly   485 IRSASFLMQYVLLMQRILICAKRNYFL----LLARIFSHIFIGVVFGYLYMNVGNNAQSVLGNYV 545
             .|.||..|:..:::|..    ||..|    .:|:|...||:.:|.|.::..|..|:..:.....
Zfish   363 -YSTSFCHQFHWVLKRTF----RNLMLNPQTSVAQIGVMIFLALVVGAIFFGVAENSSGIQNRMG 422

  Fly   546 YLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLS-LISFEIPFQSLCTAMYIII 609
            .|:..|....::...|..| |..|..:...|:.:.:|::..|||| ::|..:..:::...::..:
Zfish   423 ALFFITTNQCFSSVSAAEL-FIAERKLFVHEYISGYYRVSVYFLSKILSDILTLRTIPAVIFSCV 486

  Fly   610 SVHLTG-NDATDSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLAVFLGPILAVMFSVFG--FC 671
            :..:.| ..|.::|.|:.|.:  ||.|.:|.|....:.|   .:..|.:..|...:..||.  |.
Zfish   487 AYFMIGLKPAAEAFFIFLFSI--IMVSYTATAMTLAISA---DQTVVAIANIFMTISFVFMMIFS 546

  Fly   672 TRYIDITPLFRWMWHLSYFRAGFHGALNAI 701
            ...:::..:..|:..|.||....:| |:|:
Zfish   547 GLLVNLPSVATWLNWLKYFSIPRYG-LSAL 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	87/233 (37%)
		3a01204	123..765	CDD:273361	162/597 (27%)
		ABC2_membrane	497..698	CDD:279410	46/208 (22%)
abcg2a	XP_021325521.1	PRK10535	43..638	CDD:333000	165/605 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920