Protein Alignment CG17646 and abcg2

DIOPT Version :10

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: XP_012819987.2
• Gene: abcg2 / 734088
• XenbaseID: XB-GENE-991895
• Length: 682
• Species: Xenopus tropicalis
• Alignment Length: 604
• Identity: 163/604 - (26%)
• Similarity: 289/604 - (47%)
• Gaps: 74/604 - (12%)

  Fly   106 IQFADVRYTVKKFS--FPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCS-T 167
            :.|.::.|.||..|  ...||...:.||:.:||..|.| |.||:||:|:|||:||:|::.... .
 Frog    56 LSFYNINYKVKVKSGLICCRKVTERVILNDVNGIMRPG-LNAILGPTGSGKSSLLDVLAARKDPN 119

  Fly   168 GVSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIK 232
            |:||.:.|:.:|. ||:  |:.:..|:.|||::...|.:.|.:..:|.|:|...|.:..|.:.|.
 Frog   120 GLSGQVLVDGEPQ-PSN--FKCLSGYVVQDDVVMGTLSIRENLQFSAALRLPRSVKQKEKDERIN 181

  Fly   233 HILSLLGLDHRYNVPTGK-----LSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVAL 292
            .::..|||....:...|.     :|||::||..|.:|||::|.:|:|||||||||:|:.::.:.|
 Frog   182 QVIKELGLTKVADSKVGTQFIRGVSGGERKRTNIGMELITDPGILFLDEPTTGLDASTANAVLLL 246

  Fly   293 LKKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPAD 357
            ||:::.||.||:.:||||...||.:||.|..:..|..::.||.|:.:.:.......|.|::||||
 Frog   247 LKRMSRQGKTIIFSIHQPRYSIFRLFDSLTLLAGGRLLFHGPSRDALDYFTGLGYECESHNNPAD 311

  Fly   358 YLLEVAVGEHQR-DLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALA 421
            :.|::..|:... .||:|         |||         ::....:.:.:| |.|.||:.
 Frog   312 FFLDIINGDSTAVALNKL---------EDV---------ELENEQKEVNDN-GSKTVVEN----- 352

  Fly   422 AFAAAQFSSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELARPPNAIR 486
              .:.||.:..|...:..||     :.:|.|.:                  .|:...||  ....
 Frog   353 --LSEQFCTTSYYLETKAEL-----EKMSLGKK------------------IKSNFFAR--QITY 390

  Fly   487 SASFLMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLGNYVYLYGST 551
            :.|||.|...:.:|......||....:|::...:.:.::.|.::..|..:...:......|:..|
 Frog   391 NTSFLHQLKWVCKRSFKNLWRNPQASIAQVMVTLVLALIVGAIFFGVKEDVSGIQNRVGSLFFVT 455

  Fly   552 LLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLS-LISFEIPFQSLCTAMYIIISVHLTG 615
            ....::...|:.| |.:|..:...|:.:.:|:|..||.: |.:..:|.::|.:.::..:...:.|
 Frog   456 TNQCFSSVSAIEL-FIVEKKIFIHEYISGYYRLSAYFFAKLFTDLLPMRTLPSIIFTSVIYFMIG 519

  Fly   616 NDAT-DSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLAVFLGPILAVMFSVFG--FCTRYIDI 677
            ..|| .:|....|.|:.|..:.::.|.....|..:     |.:..:|..:..||.  |....:::
 Frog   520 FKATAGAFFTMMFTLMMIAYTAASMALAVAAGQDV-----VAVANLLMTICFVFMIIFSGLLVNL 579

  Fly   678 TPLFRWMWHLSYFRAGFHG 696
            |.:..|:..|.||....:|
 Frog   580 TSVMDWISWLKYFSIPRYG 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	3a01204	123..765	CDD:273361	158/585 (27%)
abcg2	XP_012819987.2	3a01204	73..675	CDD:273361	158/587 (27%)