Protein Alignment CG17646 and abcg2b

DIOPT Version :10

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_001034155.1
• Gene: abcg2b / 570453
• ZFINID: ZDB-GENE-050517-36
• Length: 618
• Species: Danio rerio
• Alignment Length: 625
• Identity: 159/625 - (25%)
• Similarity: 290/625 - (46%)
• Gaps: 116/625 - (18%)

  Fly   106 IQFADVRYTVKKF------SFPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGF 164
            :.:.::.|.:::.      ..|||     :||..::|..::| |.||||.:|:||::||:||:|.
Zfish    28 LTYQNIHYCIRESRGLCCKKAPER-----DILKNVSGIMKTG-LNAIMGATGSGKTSLLDVMAGR 86

  Fly   165 CS-TGV-SGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKL-GFKVTKAY 226
            .. .|: ||.:.|:.|.:   :...|.|..|:.|||:|...|.|.|.:|.:.:|:| ..:.:.|.
Zfish    87 KDPRGLRSGQVLVDNKLV---TSDLRLMSAYVVQDDVLMGTLTVRENLLFSGNLRLPREQFSSAD 148

  Fly   227 KMDLIKHILSLLGLDHRYNVPTGK-----LSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSC 286
            |...::.|:..|||:...:...|.     :|||::||.:|.:|||::|.:|:||||||||||::.
Zfish   149 KKKKVESIIEELGLEDCADTKIGTEFIRGVSGGERKRCSIGMELITSPTLLFLDEPTTGLDSNTA 213

  Fly   287 SSCVALLKKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPS 351
            :|.:|||.:|:..|.||:.:||||...||.:||.|..:..|..:|.||..:.:.:.........:
Zfish   214 NSIIALLHRLSRGGRTIIFSIHQPRYSIFRLFDYLTLMHKGETVYAGPAGKAIDYFQSLGYERDA 278

  Fly   352 YHNPADYLLEVAVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKT 416
            ::||||:.|::..||....:                                           .|
Zfish   279 FNNPADFFLDITNGETATSM-------------------------------------------PT 300

  Fly   417 SEALA-AFAAAQF-SSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELA 479
            .::|| .:..:|| ::.|           ||:|.::|..:|                |::|  .:
Zfish   301 EKSLAELYRESQFCTAVD-----------EELKCITGPSDS----------------LSEA--KS 336

  Fly   480 RPPNAIRSASFLMQYVLLMQRILIC--AKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLG 542
            :.|:.:.|.|:.::.|.....:.:.  .:.:|..:...|...:.||:|:..:.:.:....|:.:|
Zfish   337 KAPSYVTSFSYQLKVVCWRTGLNVVRNPQTSYAQIAMNILFALLIGLVYYQMPLTLPEALQNRIG 401

  Fly   543 NYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLISFE-IPFQSLCTAMY 606
            .:.:|    ::.:..|.::.|..|..|..:...|:...:|:...||||.:..: :|.:.:...::
Zfish   402 AFFFL----IINMVFGNLSAVELFINERAIFVHENSGGYYRTSVYFLSKVFVDLLPNRIVPILIF 462

  Fly   607 IIISVHLTG-NDATDSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLAVFLGPILAVMFSVF-- 668
            ..||.::.| |.|..||  ..|.|...:.||:..:..|.|.|::.|   ..:..||.|:..||
Zfish   463 SSISYYMMGLNPAFTSF--LCFALTVSLVSLAGVSLAFLVSASVST---FAMANILVVLPFVFMM 522

  Fly   669 ---GFCTRYIDITPLFRWMWHLSYFRAGFHG-ALNAIYGM 704
               ||......:.....|:...|.|:.|... .:|.:.|:
Zfish   523 VFGGFLVNLNSMLNWLSWLKWTSIFKYGLDAVTINEMKGL 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	3a01204	123..765	CDD:273361	156/602 (26%)
abcg2b	NP_001034155.1	3a01204	41..616	CDD:273361	158/612 (26%)