Protein Alignment CG17646 and abcg5

DIOPT Version :9

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_001122162.1
• Gene: abcg5 / 557317
• ZFINID: ZDB-GENE-050517-40
• Length: 652
• Species: Danio rerio
• Alignment Length: 670
• Identity: 152/670 - (22%)
• Similarity: 278/670 - (41%)
• Gaps: 149/670 - (22%)

  Fly    79 NDLNGFQSPNYHQAVAHANFDHCDPVD-IQFADVRYTVKK--------FSFPERKFVTKEILHGL 134
            |.|||..........|.:|.|:.:|.. :...:|.|:|.:        .||  ||..|::||:.:
Zfish    14 NGLNGSFKVVSEMETARSNPDYIEPSSCLSVKNVSYSVSERVGPWWDLSSF--RKKWTRQILNEV 76

  Fly   135 NGSFRSGELTAIMGPSGAGKSTLLNVMSGFC--STGVSGDIRVNRKPMAPSSERFRQMLCYIHQD 197
            :....||::..|:|.||:||:|||:.::|..  |..:.|::.||.:.:  ..|:|:....|:.|.
Zfish    77 SFHLDSGQIMGILGNSGSGKTTLLDAIAGRIGNSGNLQGEVFVNGRKL--KREQFQDCFSYVLQS 139

  Fly   198 DLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGLDH-RYNVPTGK----LSGGQKK 257
            |.|...|.|.|.:...|.|.|.....:|.:.. :..:::.|.|.| .::|..|:    :|||:::
Zfish   140 DNLLSYLTVEETLTYTAQLALRKHSAEAIRKK-VTAVMAELSLGHVAHSVIGGRVFPGISGGERR 203

  Fly   258 RLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQPSALIFEMFDKLY 322
            |::||.:|:.:|.|:.||||||||||.:.:..|.||.:||.:...::.|||||.:.:|.:|:::.
Zfish   204 RVSIASQLLQDPKVILLDEPTTGLDSMTANQIVMLLAELARRDRIVIVTIHQPRSELFRIFNRIA 268

  Fly   323 TVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEVAVGEHQRDLNELIHAANKKYYEDVD 387
            .:..|..::.|...::|.|.:.....||.|.||.|..:::...:.:....|   ||..:...|:
Zfish   269 IMSQGELVFCGEPHKMVDFFSSCGYECPEYCNPFDIYVDLTSVDTRCSERE---AATYRRMHDI- 329

  Fly   388 RHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQFSSFDYVKPSPQELALEEIKALSGG 452
            ...|.:|:....:.|.|:::.
Zfish   330 TSAYQNSEIYTNMQEKIEQSC-------------------------------------------- 350

  Fly   453 PESADPDLLEKNLRPQPQPLAKAGELARPPNAIRSASFLMQYVLLMQRILICAKRNYFLLLARIF 517
             :..|..::....:..|..::|.|.|.|  ...|:.|                 |:...:|.|:.
Zfish   351 -QRPDKPMIPFKSKESPNCISKLGVLLR--RTFRNVS-----------------RDRMGILMRLS 395

  Fly   518 SHIFIGVVFGYLYMNVGNN-----AQSVLGNYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREH 577
            .::..|:...:..|.:|.:     .|..:|   .:|.|.....|||.:..|..||....:..:|.
Zfish   396 QNLIYGLFIAFFLMRLGKDVTKGAVQDRIG---LIYQSMGASPYTGMLNAVALFPALRAISDQES 457

  Fly   578 ----FNRWYKLGPYFLSLISFEI-------------------PFQSLCTAMYIIISVHLTGNDAT 619
                :.:|.....|.:.::.|.|                   |.:.||.:..:::. |:.|...|
Zfish   458 KDGLYQKWQMFLAYIIHILPFSIISVFIFASFLYWTVGMNPDPVRFLCFSAVVMVP-HIIGELLT 521

  Fly   620 DSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLAVFLGPILAVMFSVFGFCTRYIDITPLFRWM 684
                   .:|||::...:....|            |.|..|..:|.. .||...:..:..:|:|:
Zfish   522 -------LVLLGVVQDPNMVNSG------------VALLNIAGIMVG-SGFLRGFKQMPVVFQWL 566

  Fly   685 WHLSYFRAG--------FHG 696
            .:|::.:.|        |:|
Zfish   567 SYLTFQKYGCELLIVTEFYG 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	77/245 (31%)
		3a01204	123..765	CDD:273361	139/617 (23%)
		ABC2_membrane	497..698	CDD:279410	43/236 (18%)
abcg5	NP_001122162.1	3a01204	50..645	CDD:273361	142/634 (22%)
		ABCG_White	53..279	CDD:213201	73/230 (32%)
		ABC2_membrane	375..582	CDD:279410	45/249 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820