Protein Alignment CG17646 and Abcg3l2

DIOPT Version :10

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_001406030.1
• Gene: Abcg3l2 / 360910
• RGDID: 1359703
• Length: 652
• Species: Rattus norvegicus
• Alignment Length: 702
• Identity: 170/702 - (24%)
• Similarity: 300/702 - (42%)
• Gaps: 142/702 - (20%)

  Fly   102 DPVDIQFADVRY--TVKKFSFPE-RKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSG 163
            :.|.:.|.::.|  ||:. .||. :|....|.|..::|....| |.|||||....:|.||:|::.
  Rat    34 EAVVLSFHNISYIETVQS-GFPLCQKTRVMERLSSISGIMGPG-LNAIMGPQDGSRSLLLDVLAA 96

  Fly   164 FCS-TGVSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYK 227
            ... :|:||||.||.|| .|::  |:....|:..:|::...:.|.:.:..:|.|:|...:|:..|
  Rat    97 RRDPSGLSGDILVNGKP-RPAN--FKCTSGYVPHNDVVWGTVTVRDNLEFSAALRLPMTITRDEK 158

  Fly   228 MDLIKHILSLLGLDHRYNVPTGKLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVAL 292
            ...|..:|.||.||.:.|  |...|...:||.:||:|||::.|:|:||:|||.||.::.:..:::
  Rat   159 RRRINEVLELLHLDEKQN--TKPRSKELRKRTSIAVELIADHPILFLDDPTTYLDFTTTTYIISV 221

  Fly   293 LKKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPAD 357
            |::::.:|.||:.:|:||...||..||.|..|..|..|:.||.|:.:.:..       |...|||
  Rat   222 LRRMSMKGKTIIFSINQPQYSIFRFFDSLSLVASGKLMFHGPARDALEYFT-------SAGYPAD 279

  Fly   358 YLLEV-------------AVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESI-KENM 408
            :.|::             .||.:: :|.|..:.|.||......:.| :.||..|||.:.: ::.:
  Rat   280 FFLDIINGGFCDTEEDGHEVGNYE-ELFERQYQATKKLVNMYAQSR-LHSDTRARLDQILGQQQL 342

  Fly   409 GGKAVVKTSEALAAFAAAQ---FSSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQ 470
            ...:.|:|:.|...:....   :.||                               ||:|
  Rat   343 DRNSAVETTCATPFWHQLMWITYQSF-------------------------------KNIR---- 372

  Fly   471 PLAKAGELARPPNAIRSASFLMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGN 535
                              .||:  |.::|.::            ::.....:|:.|.:| .|..|
  Rat   373 ------------------GFLL--VTVIQAVI------------KVTLAALVGITFQFL-ENDCN 404

  Fly   536 NAQSVLG-NYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQ 599
            ..|...| .|:......:..|..||:     |.::.|....||.:.:|::..||...:..::..:
  Rat   405 EVQIRAGLLYLLTIFQCIASVGVGKL-----FVIDRDRFLHEHTSGYYRMSCYFFGKLLADLIPR 464

  Fly   600 SLCTAMYIIISVHLTGNDATDSFRIYYFMLLGI-MASLSAQAWGFFVGATLPTKLAVFLGPILAV 663
            .|..:..::|:..:.|...  |...::.||..: |...|..:....:||   .|.||.:..:|..
  Rat   465 RLLPSTIVLITYFIAGGRM--SMSSFFAMLFTVMMLDFSVSSLPLSIGA---GKNAVAVPKLLVT 524

  Fly   664 MFSVF-----GFCTRYIDITPLFRWMWHLSYFRAGFHGAL-NAIYGMDRPFLECPETAM----YC 718
            ::.||     |.......:.|...|:.:.|....||...| |...|.:    .|||..|    .|
  Rat   525 IYFVFMLFFSGLSLYSGSLPPQLSWIQYFSILHYGFKALLHNEFLGQN----FCPEDTMEELSRC 585

  Fly   719 HFRSPKVFLKYMMISDVHMSD-----------CLILMGIVIGVMHVLTLITL 759
            |........:::.|..:.:|.           |::::.:.|..:.:|.:.||
  Rat   586 HNYVICAGEEFLAIQGIDLSSWGFWENHLALACIMIILLTITYVQLLQVKTL 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	3a01204	123..765	CDD:273361	163/678 (24%)
Abcg3l2	NP_001406030.1	3a01204	54..632	CDD:273361	161/674 (24%)