DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and Atet

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster

Alignment Length:	864	Identity:	286/864 - (33%)
Similarity:	430/864 - (49%)	Gaps:	164/864 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLPDIKA----SD-AACCVGGANSDASSSSGVCSLKGHHGDPDSGCLGINCCTTAAS------SE 56
            :||..|:    || ||.....|....|.:..:.:|....|:|:.   ..|..|.:..      |:
  Fly    21 ILPAAKSPNRVSDSAATTAPNAVLYTSGNMSLSTLSTGSGNPNP---NPNASTNSRQEPVPLLSQ 82

  Fly    57 LSIDETSSTSSRGS----CE---------LTSKVTNDLNGFQSPNYHQ--AVAHANFDHCDPVDI 106
            |.:......:|.||    |.         |..||.|:..|  |||..:  .:|.::.....||||
  Fly    83 LKLTNDLKQNSHGSQNNLCNGGLGSNNHALAPKVANNSGG--SPNGQKKGTIALSHLPQRPPVDI 145

  Fly   107 QFADVRYTVKKFSFPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCSTGVSG 171
            :|.|:.|:|.  ....|.|  |.||..::|.||:||:||||||||||||||:|:::|:.:..:||
  Fly   146 EFCDISYSVT--DSHRRGF--KTILKSVSGKFRNGEITAIMGPSGAGKSTLMNILAGYKTAQLSG 206

  Fly   172 DIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILS 236
            .:.:|.|..  :..|||::.|||.|||:|...|.|.|.|::||:||||..:....|:.:::.||.
  Fly   207 SVLINSKER--NLRRFRKLSCYIMQDDVLIANLTVREAMMVAANLKLGKNMISYAKVVVVEEILE 269

  Fly   237 LLGLDHRYNVPTGKLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGH 301
            .:||....|..|..|||||:|||:|||||::||||::.||||:|||||:|...::||:.||..|.
  Fly   270 TIGLKESVNTLTCNLSGGQRKRLSIALELVNNPPVMFFDEPTSGLDSSTCFQLISLLRSLARGGR 334

  Fly   302 TIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEVAVGE 366
            |||||||||||.:||.||.||.:..|.|:|:|.|:.|||:|:.....||||||||||:||||.||
  Fly   335 TIVCTIHQPSARLFEKFDHLYLLAQGQCVYEGRVKGLVPYLSSLGYECPSYHNPADYVLEVASGE 399

  Fly   367 HQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQFSSF 431
            :                                          |.||.|..:|:.:.|..:::..
  Fly   400 Y------------------------------------------GDAVPKLVDAVKSGACKKYAHK 422

  Fly   432 DYVKPSPQELALEE-IKALSGGPESA---------DPDLLEKNLRPQPQPLAKAGELARPP---- 482
            |||....|:....: ||....|.|:|         .|.|.::.|.|. .|:....|| :||
  Fly   423 DYVLTLAQKGCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPS-IPVDDPAEL-KPPKLET 485

  Fly   483 ---------------NAI-RSASF----------------------------------------- 490
                           ||: .|.||
  Fly   486 QQSQNSDCSVVNMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNK 550

  Fly   491 -------LMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLGNYVYLY 548
                   ..|:.:|::|......|:..|...|:|||:.:|.:.|.:|.:|||.|..::.|...::
  Fly   551 TGFPTSGWTQFWILLKRSFRTILRDKMLTHMRLFSHVIVGAIIGMIYYDVGNEASKIMSNAGCIF 615

  Fly   549 GSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQSLCTAMYIIISVHL 613
            ..:|...:|..|..:||||.|:.:..|||.|.||.|..::.:....::|||.:.:::|:::..:|
  Fly   616 FVSLFTTFTAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQIVFSSVYVLVVYYL 680

  Fly   614 TGNDATDSFRIYYFMLLGIMASLSAQAWGFFVGATLPTKLAVFLGPILAVMFSVF-GFCTRYIDI 677
            | :...:..|:..|:|:.::.||.||:.|..:||.:..:..|||||:..:...:| ||...:..|
  Fly   681 T-SQPMELERVSMFVLICVLNSLVAQSLGLLIGAGMNIETGVFLGPVTTIPTILFSGFFVNFDTI 744

  Fly   678 TPLFRWMWHLSYFRAGFHGALNAIYGMDRPFLECPETAMYCHFRSPKVFLKYM-MISDVHMSDCL 741
            ....:|:.::||.|.||.||:.|||||||..::|.:  ||||:|.||.||:.| |.:.:...|.:
  Fly   745 PGYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQCNQ--MYCHYRVPKKFLEEMSMDNALFWVDAV 807

  Fly   742 ILMGIVIGVMHVLTLITLW 760
            .|:||...:..:...:..|
  Fly   808 ALIGIFFALRIIAYFVLRW 826

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	117/229 (51%)
		3a01204	123..765	CDD:273361	249/718 (35%)
		ABC2_membrane	497..698	CDD:279410	63/201 (31%)
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	256/740 (35%)
		ABCG_EPDR	142..366	CDD:213180	117/229 (51%)
		ABC2_membrane	564..767	CDD:279410	64/203 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		mtm14984
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
	8	7.920