DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17646 and CG9663

DIOPT Version :9

Sequence 1:	NP_608618.1	Gene:	CG17646 / 33354	FlyBaseID:	FBgn0264494	Length:	766	Species:	Drosophila melanogaster
Sequence 2:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster

Alignment Length:	785	Identity:	268/785 - (34%)
Similarity:	401/785 - (51%)	Gaps:	76/785 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTLLPDIKASDAACCVGGANSDASSSSGVCSLKGHHGDPDSGCLGINCCTTAASSELSIDETSST 65
            :||....|:.||. .....|:..|:|..|      :|.|    ||    .|..||..:..:.|..
  Fly    65 LTLNIKAKSHDAP-LAETENTVLSTSESV------YGTP----LG----ATPVSSPANQSQRSQA 114

  Fly    66 SSRGSCELTSKVTNDLNGFQSPNYHQAVAHANFDHCDPVDIQFADVRYTVKKFSFPERKFVTKEI 130
            |........:..|....|...|       |..:.....::|.|.::|||. ||...:|:  ||::
  Fly   115 SQHSDESRNTSSTATSGGSIFP-------HEQYKTIKKINIGFENIRYTT-KFGVFQRE--TKDV 169

  Fly   131 LHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCSTGVSGDIRV--NRKPMAPSSERFRQMLCY 193
            |.||.|.|:||||:|::||||||||||||::||:.:.|.:||.||  ||:.:    :.|:..:.:
  Fly   170 LMGLTGYFKSGELSAVIGPSGAGKSTLLNILSGYTTYGFTGDFRVNGNRRDL----KAFKSNVAF 230

  Fly   194 IHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGLDHRYNVPTGKLSGGQKKR 258
            |.||..|:..|.|.|.|..||:||:|..:|.:.|.:.:|.||..:|:....:..||:||||||||
  Fly   231 IRQDTSLQAFLSVKEAMHFAANLKIGTHMTHSEKRERVKCILEAIGMYENRHTRTGQLSGGQKKR 295

  Fly   259 LAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQPSALIFEMFDKLYT 323
            |||||||::|||||.||||||||||.:.:..:.||||||.:|.|::|||||||||.|.|||.||.
  Fly   296 LAIALELVNNPPVLILDEPTTGLDSFTSNQLINLLKKLAIEGRTVICTIHQPSALTFAMFDHLYA 360

  Fly   324 VVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEVAVGEH----QRDLNELIHAANKKYYE 384
            :.:|.|:|.|..:.|:|||....|.||..:||||||:|:|..::    ...|.:|:...:....|
  Fly   361 IGEGKCIYAGGAQNLLPFLGALNLHCPESYNPADYLMEIATHDYDTAEDNQLEKLVALMDNGRNE 425

  Fly   385 DVDRHRYMSSDDMARLVESIKENM---GGKAVVKTSEALAAFAAAQFSSFDYVKPSPQELALEEI 446
            |   :|...:..:|:|....|.:.   .|.....|:..::....|.|...:..||      |..|
  Fly   426 D---YRQSKTARVAQLAAMKKVDQLMAAGLITPVTAPVMSTSVPAHFMQGNTFKP------LTPI 481

  Fly   447 KALS-----------GGPESADPDLLEKNLRP----QPQPLAKAGELARPPNAIRSASFLMQYVL 496
            ..||           |...|......:...||    .|..|.|...:...|       |..|..:
  Fly   482 NELSSRVWDSQTAGIGNAGSCCKPKKKNKSRPAIELDPSHLCKRQNIYATP-------FYRQLSI 539

  Fly   497 LMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLGNYVYLYGSTLLLVYTGKMA 561
            |:.|..:...|:..|...|...|:..|::.|.||..:||:|...|..:.||:.:.:.::|.....
  Fly   540 LLVRTFLLIWRDSSLTTMRFAIHLITGILIGTLYFGIGNDAAQTLNIFRYLFYTIMFIMYCAFSG 604

  Fly   562 VVLTFPLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQSLCTAMYIIISVHLTGNDATDSFRIYY 626
            :::.||||..:::||||||||.|..|::::...::|.|.:|:|:: |:..:|......:.:|...
  Fly   605 ILVKFPLEFPIVSREHFNRWYSLRAYYVAITLADLPIQIICSALF-IVPTYLMTQQPLELWRFGM 668

  Fly   627 FMLLGIMASLSAQAWGFFVGATLPTKLAVFLGPILAVMFSVF-GFCTRYIDITPLFRWMWHLSYF 690
            |.|:..:.:|.:|:.|..|||.|..||...|||.....|..| ||.....|.....|||:.:|:.
  Fly   669 FFLIVFVTALVSQSIGLAVGAALSLKLGSILGPFFICPFLQFSGFFLMEKDAPVFLRWMFDISFL 733

  Fly   691 RAGFHGALNAIYGMDRPFLECPETAMYCHFRSPKVFLKYMMISDVHMSDCLILMGIVIGVMHVLT 755
            :....||..||:|.||..|.|.|  :|||.|.|:..||.:.:::.:.:..||.:   .||:..|.
  Fly   734 KYSLEGATMAIFGYDREPLACNE--LYCHLRHPQFILKSLDMANGNYTLALIFL---FGVLVFLR 793

  Fly   756 LITLW 760
            ::..:
  Fly   794 ILAFY 798

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	119/231 (52%)
		3a01204	123..765	CDD:273361	239/663 (36%)
		ABC2_membrane	497..698	CDD:279410	62/201 (31%)
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	119/231 (52%)
		3a01204	149..808	CDD:273361	245/679 (36%)
		ABC2_membrane	540..743	CDD:279410	63/203 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		mtm14984
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
	8	7.920