Protein Alignment CG17646 and Abcg5

DIOPT Version :9

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_114090.1
• Gene: Abcg5 / 27409
• MGIID: 1351659
• Length: 652
• Species: Mus musculus
• Alignment Length: 762
• Identity: 169/762 - (22%)
• Similarity: 306/762 - (40%)
• Gaps: 217/762 - (28%)

  Fly    67 SRGSCELTSKVTNDLNGFQSPNYHQAVAHANFDHCDPVDIQFADVRYTVKKFSFPERKFVTKEIL 131
            :|||  |:|.....:.|.:: .:...|.|.::...:.|. .:.:::...:|:.        ::||
Mouse    18 NRGS--LSSLEQGSVTGTEA-RHSLGVLHVSYSVSNRVG-PWWNIKSCQQKWD--------RQIL 70

  Fly   132 HGLNGSFRSGELTAIMGPSGAGKSTLLNVMSG-FCSTG-VSGDIRVNRKPMAPSSERFRQMLCYI 194
            ..::....||::..|:|.||:||:|||:.:|| ...|| :.|::.||...:  ..::|:....|:
Mouse    71 KDVSLYIESGQIMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVFVNGCEL--RRDQFQDCFSYV 133

  Fly   195 HQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGLDH-------RYNVPTGKLS 252
            .|.|:....|.|.|.:...|.|.|.......|... ::.:::.|.|.|       .||.  |.:|
Mouse   134 LQSDVFLSSLTVRETLRYTAMLALCRSSADFYNKK-VEAVMTELSLSHVADQMIGSYNF--GGIS 195

  Fly   253 GGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQPSALIFEM 317
            .|:::|::||.:|:.:|.|:.|||||||||..:.:..|.||.:||.:...::.|||||.:.:|:.
Mouse   196 SGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANQIVLLLAELARRDRIVIVTIHQPRSELFQH 260

  Fly   318 FDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADY---LLEVAVGEHQRDLN-----EL 374
            |||:..:..|..::.|...|::.|..:....||.:.||.|:   |..|.....:|::.     ::
Mouse   261 FDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFYMDLTSVDTQSREREIETYKRVQM 325

  Fly   375 IHAANK------KYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAFAAAQFSSFDY 433
            :..|.|      |..|:::|.||
Mouse   326 LECAFKESDIYHKILENIERARY------------------------------------------ 348

  Fly   434 VKPSPQELALEEIKALSGGP-ESADPDLLEKNLRPQPQPLAKAGELARPPNAIRSASFLMQYVLL 497
                        :|.|...| ::.||          |....|.|                   :|
Mouse   349 ------------LKTLPTVPFKTKDP----------PGMFGKLG-------------------VL 372

  Fly   498 MQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGNN-----AQSVLGNYVYLYGSTLLLVYT 557
            ::|:.....||...::.|:..::.:|:...:..:.|.||     .|..:|....|.|:|   .||
Mouse   373 LRRVTRNLMRNKQAVIMRLVQNLIMGLFLIFYLLRVQNNTLKGAVQDRVGLLYQLVGAT---PYT 434

  Fly   558 GKMAVVLTFPLEIDMLTREH----FNRWYKLGPYFLSLISFE----IPFQSLC---TAMY----- 606
            |.:..|..||:...:..:|.    :::|..|..|.|.::.|.    :.|.|:|   ..:|
Mouse   435 GMLNAVNLFPMLRAVSDQESQDGLYHKWQMLLAYVLHVLPFSVIATVIFSSVCYWTLGLYPEVAR 499

  Fly   607 ------IIISVHLTGNDATDSFRIYYFMLLG----------IMASLSAQAWGFFVGA-------T 648
                  .:::.||.|...|       .:|||          |:|.||..  |..:|:       .
Mouse   500 FGYFSAALLAPHLIGEFLT-------LVLLGIVQNPNIVNSIVALLSIS--GLLIGSGFIRNIQE 555

  Fly   649 LPTKLAVFLGPILAVMFSVFGFCTRYIDITPLFRWMWHLSYFRAGFHGALNAIYGMDRP------ 707
            :|..|.: ||     .|:...:|...:.:...:    .|::...|.:.::     ::.|
Mouse   556 MPIPLKI-LG-----YFTFQKYCCEILVVNEFY----GLNFTCGGSNTSM-----LNHPMCAITQ 605

  Fly   708 ---FLE--CP-ETAMYCHFRSPKVFLKYMMISDVHMSDCLILMGIVI 748
               |:|  || .|:.:    :....:.|..|      ..|:::||||
Mouse   606 GVQFIEKTCPGATSRF----TANFLILYGFI------PALVILGIVI 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	ABCG_EPDR	103..333	CDD:213180	71/238 (30%)
		3a01204	123..765	CDD:273361	159/706 (23%)
		ABC2_membrane	497..698	CDD:279410	51/244 (21%)
Abcg5	NP_114090.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		4/8 (50%)
		ABCG_White	50..276	CDD:213201	71/239 (30%)
		3a01204	61..646	CDD:273361	160/715 (22%)
		ABC2_membrane	372..579	CDD:279410	49/224 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820