Protein Alignment CG17646 and wht-5

DIOPT Version :10

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_502352.1
• Gene: wht-5 / 178182
• WormBaseID: WBGene00008950
• Length: 695
• Species: Caenorhabditis elegans
• Alignment Length: 766
• Identity: 180/766 - (23%)
• Similarity: 305/766 - (39%)
• Gaps: 174/766 - (22%)

  Fly    46 INCCTTAASSELSIDETSSTSSRGSCELTSKVTNDLNGFQSPNYHQAVAHANFDHCDPVDIQFAD 110
            ||....|:..|....|.:.:|.|.....|..||||....:.|:  |...:|.       .:.|.:
 Worm    48 INDTPVASEIEQVEKELAHSSERFRKPKTLSVTNDTESARIPS--QVKTNAK-------KLVFQN 103

  Fly   111 VRYTVKKFSFPERKFVTKEILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSG--FCSTGVSGDI 173
            ::..|.|     :|.|.:|||..::|..|.||||.|||.|||||:||||:::|  ..:....|||
 Worm   104 IQAVVLK-----KKGVRQEILKKIDGVARPGELTFIMGSSGAGKTTLLNILTGRNLKNIETDGDI 163

  Fly   174 RVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLK----LGFKVTKAYKMD-LIKH 233
            .:|.:.|.  |...:::..|:.|||:....|.|.|.:..||.|:    ||     |.::| ::..
 Worm   164 MINGRNMI--SNEMKKLSAYVQQDDVFIGTLTVRETLRFAAKLRSPSALG-----ATELDSIVDE 221

  Fly   234 ILSLLGLDHRYNVPTG-----KLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALL 293
            :|.::.|....|...|     .||.|::||||.|.|::::||:|:.||||:||||......:..|
 Worm   222 LLVMMSLKKCENTKVGTMTEKSLSRGERKRLAFACEILTDPPILFCDEPTSGLDSFMSHQVIKAL 286

  Fly   294 KKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADY 358
            ::|..:|.|::|||||||..::.|.|:|..:..||..|.||.:::..|........|.:.:..|:
 Worm   287 RQLTIEGKTVICTIHQPSTSVYHMADQLILLSQGHVAYAGPAKQVDAFFGRCGYPIPKFVSSPDH 351

  Fly   359 LLEVAVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEALAAF 423
            .:.|                       :....:.:.||..:.:|.|
 Worm   352 FMRV-----------------------ISHKSFETEDDYNKRIEKI------------------- 374

  Fly   424 AAAQFSSFDYVKPSPQELALEEIKALSGGPESADPDLLEKNLRPQPQPLAKAGELARPPNAIRSA 488
                ....|.:|                 .|.:....|..:.|..|:                :|
 Worm   375 ----VLEHDIMK-----------------KEQSTHSTLSSSRREHPE----------------TA 402

  Fly   489 SFLM------QYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFGYLYMNVGNNAQSVLGNYVYL 547
            .|..      |:..:.||..|...|...:||.::...:.:.::.|..|..:..:.:|:.....:.
 Worm   403 PFTFPRTWTAQFFFIFQRSSIQLWRERSVLLVKLIQTLIMSIMIGSTYYGLEIDKKSLPSFKGFA 467

  Fly   548 YGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLS--------LISFEIPFQSLCTA 604
            :.|..::.....|..:..|..:..::.||.....|....|:|:        .:.|.:.|..:...
 Worm   468 FVSVQMMHMLFMMPAMTVFWKDYPVVVREFQANMYSPSAYYLAKTTADSIQYLVFPVIFSGILLG 532

  Fly   605 MYII-ISVHLTGNDATDSFRIYYFMLLGIMASLSAQAWGFFVGAT---LPTKLAVFLGPILAVMF 665
            |..: .||.:..|          ::::.|:.||:|.:.|....|.   |.|.:.|.  ||:.|..
 Worm   533 MTSLPYSVVIITN----------YLIINILLSLNACSVGQSFAAMCGHLATGMTVL--PIVCVPL 585

  Fly   666 SVF-GFCTRYIDI----TPLFRWMWHLSYFRAGFHGALNAIYGMDRPFLECPETAMYCHFRSPKV 725
            .|| ||...|..|    .| |.|   :|:::.||. |:..:|      .....|...|...|...
 Worm   586 MVFGGFMITYEAIPWYFLP-FAW---VSWYKYGFE-AITIVY------FNHNSTISGCESNSSVA 639

  Fly   726 ---------------FLKYMMISDVHM-SDCLILMGIVIGVMHVLTLITLW 760
                           |:|.....:.|: .|..:::.:::....:..|:..|
 Worm   640 TLKMSIDSNCTTGIEFIKAQAFEETHLWLDYTVILAVILFWKILGALLFTW 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	3a01204	123..765	CDD:273361	162/689 (24%)
wht-5	NP_502352.1	3a01204	88..695	CDD:273361	168/726 (23%)