Protein Alignment CG17646 and w

DIOPT Version :10

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: XP_061509581.1
• Gene: w / 1271671
• VectorBaseID: AGAMI1_013186
• Length: 722
• Species: Anopheles gambiae
• Alignment Length: 814
• Identity: 193/814 - (23%)
• Similarity: 328/814 - (40%)
• Gaps: 196/814 - (24%)

  Fly    36 HGDPDSGCLGINCCTTAASS---------ELSIDETSSTSSRGSCELTSKVTND---LNGFQSPN 88
            :||.:|.       ||.:||         :.|:|:..:|:          :|||   |.....|.
Mosquito     9 YGDAESK-------TTISSSRRYSSSSYQDQSMDDALNTT----------LTNDKATLIQVWKPK 56

  Fly    89 YHQAVAHANFDHCDPVDIQFADVRYTVKKFSF---------PERKFVT----------------K 128
            .:.:| ......|:       .:.||.|:...         |.....|                |
Mosquito    57 SYGSV-KGQIPQCE-------RLTYTWKEIDVFGEAPTDGKPREPLCTRLRNCCTRQRKDFNPRK 113

  Fly   129 EILHGLNGSFRSGELTAIMGPSGAGKSTLLNVMSGFCSTGVS---GDIR-VNRKPMAPSSERFRQ 189
            .:|..:.|..:||||.|:||.|||||:||||.::.....||.   ..:| :|..|:  ::|:.|.
Mosquito   114 HLLKNVTGVAKSGELLAVMGSSGAGKTTLLNALAFRSPPGVKISPNAVRALNGVPV--NAEQLRA 176

  Fly   190 MLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGL----DHRYNVPTGK 250
            ...|:.||||..|.|...|.:|..|.|::|..|..:.|...::.:|..|.|    |.....| |:
Mosquito   177 RCAYVQQDDLFIPSLTTREHLLFQAMLRMGRDVPASVKQHRVQEVLQELSLVKCADTIIGAP-GR 240

  Fly   251 ---LSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQPSA 312
               ||||::||||.|.|.:::|.:|..||||:||||....|.:.:||.:|.:|.||:.||||||:
Mosquito   241 IKGLSGGERKRLAFASETLTDPHLLLCDEPTSGLDSFMAHSVLQVLKGMAMKGKTIILTIHQPSS 305

  Fly   313 LIFEMFDKLYTVVDGHCMYQGPVRELVPFLADQQLVCPSYHNPADYLLEV--------------- 362
            .::.:|||:..|.:|...:.|...:...|.:...:.||..:||||:.:::
Mosquito   306 ELYCLFDKILLVAEGRVAFLGSPYQSAEFFSQLGIPCPPNYNPADFYVQMLAIAPAKEAECRDMI 370

  Fly   363 -------AVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDMARLVESIKENMGGKAVVKTSEAL 420
                   ||....|::.|....|.|.          |....|.:.||.:     |....::|...
Mosquito   371 KKICDSFAVSPIAREVLETASVAGKG----------MDEPYMLQQVEGV-----GSTGYRSSWWT 420

  Fly   421 AAFAAAQFSSFDYVK-PSPQELALEEIKALSGGPESADPDL---LEKNLRPQPQPLAKAGELARP 481
            ..:.....|....:| |...::.|.:....|.||.|..|:|   ......|:||
Mosquito   421 QFYCILWRSWLSVLKDPMLVKVRLLQTAVGSRGPSSDLPELTTCFPCFFSPRPQ----------- 474

  Fly   482 PNAIRSASFLMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVF---GYLYMNVGNNAQSVLGN 543
                                          ::|.:...|:.|.|.   |  .||:..:.
Mosquito   475 ------------------------------MVATLIGSIYFGQVLDQDG--VMNINGSL------ 501

  Fly   544 YVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLISFEIPFQSLCTAMYII 608
            :::|...|...|:    ||:..|..|:.:..||..:|.|::..|||.....|:|.......::..
Mosquito   502 FLFLTNMTFQNVF----AVINVFSAELPVFLREKRSRLYRVDTYFLGKTIAELPLFIAVPFVFTS 562

  Fly   609 ISVHLTGNDATDSFRIYYFMLLGIMASLSAQAWGFFVG-ATLPTKLAVFLGPILAVMFSVF-GFC 671
            |:..:.|.....:..:....::.::|::|. ::|:.:. |:....:|:.:||.:.:.|.:| ||.
Mosquito   563 ITYPMIGLRTGATHYLTTLFIVTLVANVST-SFGYLISCASSSISMALSVGPPVVIPFLIFGGFF 626

  Fly   672 TRYIDITPLFRWMWHLSYFRAGFHGAL--------NAIYGMDRPFLECPETAMYCHFRSPKVFLK 728
            .....:...|:::.:||:||......|        :......|..:.||        ||.::.|:
Mosquito   627 LNSASVPAYFKYLSYLSWFRYANEALLINQWSTVVDGEIACTRANVTCP--------RSGEIILE 683

  Fly   729 --YMMISDVHMSDCLILMGIVIGVMHVLTLITLW 760
              ...:.|..: |...|..::: :..:..|:.||
Mosquito   684 TFNFRVEDFAL-DIACLFALIV-LFRLGALLCLW 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	3a01204	123..765	CDD:273361	172/706 (24%)
w	XP_061509581.1	None