Protein Alignment CG17646 and Abcg1

DIOPT Version :10

• Sequence 1: NP_608618.1
• Gene: CG17646 / 33354
• FlyBaseID: FBgn0264494
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_033723.1
• Gene: Abcg1 / 11307
• MGIID: 107704
• Length: 666
• Species: Mus musculus
• Alignment Length: 758
• Identity: 273/758 - (36%)
• Similarity: 401/758 - (52%)
• Gaps: 107/758 - (14%)

  Fly    12 AACCVGGANSDASSSSGVCSLKGHHGDPDSGCLGINCCTTAASSELSIDETSSTSSRGSCELTSK 76
            ||..||.|.:.:|.|:.:.       :|.|.|:.::   ...||  ::||..:....|..:   |
Mouse     6 AAFSVGTAMNASSYSAAMT-------EPKSVCVSVD---EVVSS--NVDEVETDLLNGHLK---K 55

  Fly    77 VTNDLNGFQSPNYHQAVAHANFDHCDPVDIQFADVRYTVKKFSFPE----RKFVTKEILHGLNGS 137
            |.|        |:.:|...::......|:|:|.|:.|:|     ||    :|...|.:|.|::|.
Mouse    56 VDN--------NFTEAQRFSSLPRRAAVNIEFKDLSYSV-----PEGPWWKKKGYKTLLKGISGK 107

  Fly   138 FRSGELTAIMGPSGAGKSTLLNVMSGFCSTGVSGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRP 202
            |.||||.|||||||||||||:|:::|:..||:.|.:.:|..|.  ....||::.|||.|||:|.|
Mouse   108 FNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGMPR--DLRCFRKVSCYIMQDDMLLP 170

  Fly   203 QLLVGEIMLLAAHLKLGFKVTKAYKMDLIKHILSLLGLDHRYNVPTGKLSGGQKKRLAIALELIS 267
            .|.|.|.|:::|||||..|  ...:.:::|.||:.|||....|..||.|||||:|||||||||::
Mouse   171 HLTVQEAMMVSAHLKLQEK--DEGRREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVN 233

  Fly   268 NPPVLYLDEPTTGLDSSSCSSCVALLKKLASQGHTIVCTIHQPSALIFEMFDKLYTVVDGHCMYQ 332
            ||||::.||||:||||:||...|:|:|.||..|.:||||||||||.:||:||:||.:..|.|:|:
Mouse   234 NPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYR 298

  Fly   333 GPVRELVPFLADQQLVCPSYHNPADYLLEVAVGEHQRDLNELIHAANKKYYEDVDRHRYMSSDDM 397
            |.|..|||:|.|..|.||:||||||:::|||.||:                          .|..
Mouse   299 GKVSNLVPYLRDLGLNCPTYHNPADFVMEVASGEY--------------------------GDQN 337

  Fly   398 ARLVESIKENMGGKAVVKTSEALAAFAAAQFSSFDYVKPSPQELALEEIKALSGGPESADPDLLE 462
            :|||.:::|.|                    ...||             |...||....:|.|..
Mouse   338 SRLVRAVREGM--------------------CDADY-------------KRDLGGDTDVNPFLWH 369

  Fly   463 KNLRPQPQPLAKAGELARPPNAIRSASFLMQYVLLMQRILICAKRNYFLLLARIFSHIFIGVVFG 527
            :........:......        |||.|.|:.:|.:|..:...|:..|...||.|||.||::.|
Mouse   370 RPAEEDSASMEGCHSF--------SASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIG 426

  Fly   528 YLYMNVGNNAQSVLGNYVYLYGSTLLLVYTGKMAVVLTFPLEIDMLTREHFNRWYKLGPYFLSLI 592
            .||:.:||.|:.||.|..:|:.|.|.|::...|..|||||||:.:..|||.|.||.|..|:|:..
Mouse   427 LLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKT 491

  Fly   593 SFEIPFQSLCTAMYIIISVHLTGNDATDSFRIYYFMLLGIMASLSAQAWGFFVG-ATLPTKLAVF 656
            ..::|||.:....|..|...:| :..:|:.|...|..||.|.||.||:.|..:| |:...::|.|
Mouse   492 MADVPFQIMFPVAYCSIVYWMT-SQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATF 555

  Fly   657 LGPILAVMFSVF-GFCTRYIDITPLFRWMWHLSYFRAGFHGALNAIYGMDRPFLECPETAMYCHF 720
            :||:.|:...:| ||...:..|....:||.::||.|.||.|.:.:|||:||..|.| :.|..|||
Mouse   556 VGPVTAIPVLLFSGFFVSFDTIPAYLQWMSYISYVRYGFEGVILSIYGLDREDLHC-DIAETCHF 619

  Fly   721 RSPKVFLKYMMISDVHMSDCLILMGIVIGVMHVLTLITLWHKL 763
            :..:..|:.:.:.:..:....|::||....:.::....|.:|:
Mouse   620 QKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKI 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17646	NP_608618.1	3a01204	123..765	CDD:273361	245/643 (38%)
Abcg1	NP_033723.1	3a01204	60..666	CDD:273361	254/681 (37%)