DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17652 and FCF1

DIOPT Version :9

Sequence 1:	NP_001259881.1	Gene:	CG17652 / 33353	FlyBaseID:	FBgn0031361	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_057046.1	Gene:	FCF1 / 51077	HGNCID:	20220	Length:	198	Species:	Homo sapiens

Alignment Length:	133	Identity:	42/133 - (31%)
Similarity:	70/133 - (52%)	Gaps:	9/133 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 HKTLVFFASNFDYREPYQVLIDATFCQAALQQKIGIDEQIKK--YFQCGVKLLTTQCVILESESL 72
            |.:.:||..|.....||.:|:|..|...:::.|:.:.:.:..  |.:| :..: |.||:.|.|.|
Human    51 HPSCLFFQYNTQLGPPYHILVDTNFINFSIKAKLDLVQSMMDCLYAKC-IPCI-TDCVMAEIEKL 113

  Fly    73 GAPLTGATSIVK--RFHVHKCGHEGKPVPASEC-IKSMTKDNRYVVASQDRLLQESLRKIPGRCL 134
            |.....|..|.|  ||....|.|:|  ..|.:| ::.:|:...|:||:.||.|:..:|||||..:
Human   114 GQKYRVALRIAKDPRFERLPCTHKG--TYADDCLVQRVTQHKCYIVATVDRDLKRRIRKIPGVPI 176

  Fly   135 LYL 137
            :|:
Human   177 MYI 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17652	NP_001259881.1	PIN_Fcf1-Utp23-H	2..145	CDD:189036	42/133 (32%)
FCF1	NP_057046.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..47
FCF1	NP_057046.1	PIN_Fcf1-like	57..187	CDD:350212	40/127 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1412
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810