DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Eno and ENOC

DIOPT Version :9

Sequence 1:	NP_722721.1	Gene:	Eno / 33351	FlyBaseID:	FBgn0000579	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_180516.1	Gene:	ENOC / 817505	AraportID:	AT2G29560	Length:	475	Species:	Arabidopsis thaliana

Alignment Length:	468	Identity:	238/468 - (50%)
Similarity:	314/468 - (67%)	Gaps:	17/468 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGL 97
            :.|.|.|.::...|..:::     .::|:.    ...|..:|||||.||||.|||||||.|..|:
plant    19 AVNAAVRAKTSDPVLFIAN-----HLKKAV----SSVITKVKARQILDSRGIPTVEVDLHTNKGV 74

  Fly    98 FRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMI 162
            |||:||||.|:|.:||:||||.||..|.|.||.|||.::|:.:...||  .:|...|..||..||
plant    75 FRASVPSGDSSGTYEAIELRDGDKGMYLGNSVAKAVKNINEKISEALI--GMDPKLQGQIDQAMI 137

  Fly   163 KLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAG 227
            .||.||.||:.||||||.||:|..|||||:|.|||.||::||:|...::||||||.|::||.||.
plant   138 DLDKTEKKSELGANAILAVSIAACKAGAAEKEVPLCKHLSDLSGRANMVLPVPAFTVLSGGKHAS 202

  Fly   228 NKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALN 292
            |..|:||.||||.||:.|.||::.|||.|||||.||..|.|.....||::||.||:|.|.||.|.
plant   203 NTFAIQEIMILPIGASRFEEALQWGSETYHHLKAVISEKNGGLGCNVGEDGGLAPDISSLKEGLE 267

  Fly   293 LISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPI 357
            |:.:||.:.||..||:|.:|:||:.|....:||||.|:.......:..|:.:.::|:|...|:||
plant   268 LVKEAINRTGYNDKIKIAIDIAATNFCLGTKYDLDIKSPNKSGQNFKSAEDMIDMYKEICNDYPI 332

  Fly   358 VSIEDPFDQDHWE---AWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVT 419
            ||||||||::.||   .:|:|..|   |:|||||.::|.||:..|:::.:||.||||||||||||
plant   333 VSIEDPFDKEDWEHTKYFSSLGIC---QVVGDDLLMSNSKRVERAIQESSCNALLLKVNQIGTVT 394

  Fly   420 ESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEE 484
            |:|....:|:...||.:.|||.||||||||.||.|||:||.||.|||||.||..||||:||||||
plant   395 EAIEVVKMARDAQWGVVTSHRCGETEDSFISDLSVGLATGVIKAGAPCRGERTMKYNQLLRIEEE 459

  Fly   485 IGAGVKFAGKSFR 497
            :|....:||:.::
plant   460 LGDQAVYAGEDWK 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eno	NP_722721.1	PLN00191	69..499	CDD:215095	233/432 (54%)
Eno	NP_722721.1	enolase	72..484	CDD:239429	227/414 (55%)
ENOC	NP_180516.1	PLN00191	20..475	CDD:215095	238/467 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0148
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D773373at2759
OrthoFinder	1	1.000	-	-		FOG0000613
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11902
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X347
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920