Protein Alignment Eno and Eno4

DIOPT Version :9

• Sequence 1: NP_722721.1
• Gene: Eno / 33351
• FlyBaseID: FBgn0000579
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_848804.2
• Gene: Eno4 / 226265
• MGIID: 2441717
• Length: 618
• Species: Mus musculus
• Alignment Length: 535
• Identity: 117/535 - (21%)
• Similarity: 209/535 - (39%)
• Gaps: 149/535 - (27%)

  Fly    69 TIKAIKARQIYDSRGNPTVEVDLTTELGLF-----RAAVPSG---ASTGVHEALELRDNDKANYH 125
            :|..|..:.|.|..|.||::|:::..:..|     ..|:|:.   ....:.|||:..|:::|
Mouse    67 SICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICAVAIPTHFEVVENALPEALDAEDSERA--- 128

  Fly   126 GKSVLKAVGHVNDTLGPE---LIKANLDVVDQASIDN-----FMIKLDGTENKSKF--------- 173
             ::|..||..:|.::..|   |:.:|     ||.:|:     |..|:...:.:.:.
Mouse   129 -QAVNTAVQWINQSITEELWGLVPSN-----QAEVDHRLRTFFEHKVQEDKERKELEKSQEELVP 187

  Fly   174 ------------------------------------------------GANAILGVSLAVAKAGA 190
                                                            |:.||..||||||||.|
Mouse   188 APPPVTLPPPPPPPPPPPSKKKGQKAGRRDTLLEKPVSPPEPPEPVLHGSMAIGAVSLAVAKASA 252

  Fly   191 AKKGVPLYKHIADLAGNKE----IILPVPAFNVINGGSHAGNKL-AMQEFMILPTGATSFTEAMK 250
            .....|||..:|.|..::|    ..:|:...:|::.|..:..|| .|:|.:.:|:...:..::::
Mouse   253 TLASDPLYLTLASLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVICIPSPGLTAKQSVE 317

  Fly   251 MGSEVYHHLKNVI--------KAKFGLDAT---------AVGDEGGFAPNIQSNKEALNLISDAI 298
            :..|:...:...:        :.|.|.:.:         .|...|....|..:.::.|.|:....
Mouse   318 LLLEIQKQVNRAMETLPPPKQETKKGHNGSKRAQPPITGKVSHLGCLTINYDAIEQPLLLLQGIC 382

  Fly   299 AKAGYTGKIEIG------MDVAASEF--YKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDF 355
            :..|    :|:|      ::.|..|.  |..|:|::.....||       |.::..||.:.|..:
Mouse   383 SNLG----LELGVNFHLAINCAGHELMDYSKGKYEVMVGTHKS-------AAEMVELYVDLINKY 436

  Fly   356 P-IVSIEDPFDQDHWEAWSNLTGCTDIQ---IVGDDLTVTNPKRIATAVEKKACNC--------- 407
            | |:::.|||.::..|.|.:|......:   |.|          .|:....|...|
Mouse   437 PSIIALIDPFRKEDAEQWDSLYAALASRCYLIAG----------AASGSVSKLLECRNISTLKSH 491

  Fly   408 -LLLKVNQIGTVTESI-AAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSE 470
             |::|.....|:::.: ..||:..|.......|..|..::||.: ||.||.....||.|...|.|
Mouse   492 GLIIKHTNQTTMSDLVEITHLINGKKLLAVFGSTDSESSDDSLV-DLAVGFGARFIKLGGLSRGE 555

  Fly   471 RLAKYNQILRIEEEI 485
            |:.|||::|.||||:
Mouse   556 RMTKYNRLLAIEEEL 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eno	NP_722721.1	PLN00191	69..499	CDD:215095	117/535 (22%)
		enolase	72..484	CDD:239429	114/529 (22%)
Eno4	NP_848804.2	eno	68..570	CDD:213580	116/532 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	172..235		0/62 (0%)
		TIM_phosphate_binding	<236..569	CDD:304361	87/354 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	332..353		2/20 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844282
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11902
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940