DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rim2 and YIA6

DIOPT Version :9

Sequence 1:	NP_608615.1	Gene:	Rim2 / 33350	FlyBaseID:	FBgn0031359	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_012260.1	Gene:	YIA6 / 854811	SGDID:	S000001268	Length:	373	Species:	Saccharomyces cerevisiae

Alignment Length:	348	Identity:	108/348 - (31%)
Similarity:	157/348 - (45%)	Gaps:	71/348 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ADTLIHLIAGGSAGTVGAVVTCPLEVVKTRLQSSTAFMTPSRLAENAGGGPANGGQSELLRPEQR 70
            :.|.|..::|..||.:..|..|||:|.|||||                   |.|.|:....|..|
Yeast    75 SSTQITALSGAFAGFLSGVAVCPLDVAKTRLQ-------------------AQGLQTRFENPYYR 120

  Fly    71 RKLSTTILRNRSQPQVIGGVRRIMAISHCGISSTTPKSMSIVQCLRHIVQNEGPRALFKGLGPNL 135
                                         ||..|          |..||::||||.|:|||.|.:
Yeast   121 -----------------------------GIMGT----------LSTIVRDEGPRGLYKGLVPIV 146

  Fly   136 VGVAPSRAIYFCTYSQTKNTLNSLGFVERDSPLVHIMSAASAGFVSSTATNPIWFVKTRMQLDYN 200
            :|..|:..|||..|..:|...:.: |.:.|. :....:|.:||..|:|.|||||.||||:.|..|
Yeast   147 LGYFPTWMIYFSVYEFSKKFFHGI-FPQFDF-VAQSCAAITAGAASTTLTNPIWVVKTRLMLQSN 209

  Fly   201 SKVQMT----VRQCIERVYAQGGVAAFYKGITASYFGICETMVHFVIYEFIKSKLLEQRNQRHTD 261
            .....|    ......:::.|.|..|.|.|:..|..|:....:||.|||.:|.:......:.:|:
Yeast   210 LGEHPTHYKGTFDAFRKLFYQEGFKALYAGLVPSLLGLFHVAIHFPIYEDLKVRFHCYSRENNTN 274

  Fly   262 TKGSRDFLEFMMAGAVSKTIASCIAYPHEVARTRLREEGNKYNSFWQTLHTVWK----EEGRAGL 322
               |.:....:||.:|||.|||.:.||||:.|||::.:.:..:|..:.|..:.|    :||..|.
Yeast   275 ---SINLQRLIMASSVSKMIASAVTYPHEILRTRMQLKSDIPDSIQRRLFPLIKATYAQEGLKGF 336

  Fly   323 YRGLATQLVRQIPNTAIMMATYE 345
            |.|..|.|||.||.:||.:.::|
Yeast   337 YSGFTTNLVRTIPASAITLVSFE 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rim2	NP_608615.1	Mito_carr	8..156	CDD:278578	42/147 (29%)
		Mito_carr	163..253	CDD:278578	31/93 (33%)
		Mito_carr	268..355	CDD:278578	32/82 (39%)
YIA6	NP_012260.1	Mito_carr	75..171	CDD:395101	42/154 (27%)
		Mito_carr	176..268	CDD:395101	30/92 (33%)
		Mito_carr	274..365	CDD:395101	33/89 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53601
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880