Protein Alignment Rim2 and UCP1

DIOPT Version :10

• Sequence 1: NP_608615.1
• Gene: Rim2 / 33350
• FlyBaseID: FBgn0031359
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_068605.1
• Gene: UCP1 / 7350
• HGNCID: 12517
• Length: 307
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 76/301 - (25%)
• Similarity: 117/301 - (38%)
• Gaps: 53/301 - (17%)

  Fly     2 AQNTADTL-IHLIAGGSAGTVGAVVTCPLEVVKTRLQSSTAFMTPSRLAENAGGGPANG-----G 60
            |.:...|| :.|.:.|.|..:..|:|.||:..|.|||......|.|.:......|....     |
Human     6 ASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEG 70

  Fly    61 QSEL---LRPEQRRKLSTTILR--------------NRSQPQV---------IGGVR-------- 91
            :.:|   |....:|::|:..||              ..:.|.:         .|||.
Human    71 RMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTE 135

  Fly    92 ----RIMAISHCGISSTTPKSMSIVQCLRHIVQNEGPRALFKGLGPNLVGVAPSRAIYFCTYSQT 152
                |:.|.||  :....|:........|.|...||...|:||..|||:...........||...
Human   136 VVKVRLQAQSH--LHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLM 198

  Fly   153 KNTLNSLGFVERDSPLVHIMSAASAGFVSSTATNPIWFVKTRMQLDYNSK--VQMTVRQCIERVY 215
            |........:..|.| .|::||..|||.::..::|:..||||.   .||.  ...:|..|..:|:
Human   199 KEAFVKNNILADDVP-CHLVSALIAGFCATAMSSPVDVVKTRF---INSPPGQYKSVPNCAMKVF 259

  Fly   216 AQGGVAAFYKGITASYFGICE-TMVHFVIYEFIKSKLLEQR 255
            ...|..||:||:..|:..:.. .::.||.:|.:|.:|.:.|
Human   260 TNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKRELSKSR 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rim2	NP_608615.1	Mito_carr	8..156	CDD:395101	45/191 (24%)
		Mito_carr	163..253	CDD:395101	29/92 (32%)
		Mito_carr	268..355	CDD:395101
UCP1	NP_068605.1	Mito_carr	10..104	CDD:395101	23/93 (25%)
		Solcar 1	11..102		23/90 (26%)
		Mito_carr	111..206	CDD:395101	22/96 (23%)
		Solcar 2	111..201		22/91 (24%)
		Solcar 3	210..295		28/88 (32%)
		Mito_carr	215..300	CDD:395101	27/87 (31%)