DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rim2 and slc25a36a

DIOPT Version :9

Sequence 1:	NP_608615.1	Gene:	Rim2 / 33350	FlyBaseID:	FBgn0031359	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001002667.1	Gene:	slc25a36a / 436940	ZFINID:	ZDB-GENE-040718-415	Length:	311	Species:	Danio rerio

Alignment Length:	358	Identity:	176/358 - (49%)
Similarity:	227/358 - (63%)	Gaps:	56/358 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAQNTADTLIHLIAGGSAGTVGAVVTCPLEVVKTRLQSSTAFMTPSRLAENAGGGPANGGQSELL 65
            |:|.  |||:||.|||..|||||::||||||||||||||:.....|.:
Zfish     1 MSQR--DTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTFYISEV----------------- 46

  Fly    66 RPEQRRKLSTTILRNRSQPQVIGGVRRIMAISHCGISSTTPKSMSIVQCLRHIVQNEGPRALFKG 130
                  :|||                    ::...::...|...  :.||:.|::.||||:||:|
Zfish    47 ------QLST--------------------VNGASVARMAPPGP--LHCLKLILEKEGPRSLFRG 83

  Fly   131 LGPNLVGVAPSRAIYFCTYSQTKNTLNSLGFVERDSPLVHIMSAASAGFVSSTATNPIWFVKTRM 195
            ||||||||||||||||..||.:|..||::  .:.||..||::||..|||.:.|||||||.:|||:
Zfish    84 LGPNLVGVAPSRAIYFAAYSTSKEKLNNV--FDPDSTQVHMLSAGLAGFTAITATNPIWLIKTRL 146

  Fly   196 QLDYNSKVQ--MTVRQCIERVYAQGGVAAFYKGITASYFGICETMVHFVIYEFIKSKLLEQRNQR 258
            |||..::.:  |:..:|:.|||...|:..||:|::|||.||.||::||||||.||.||:|.:...
Zfish   147 QLDARNRGERRMSAFECVRRVYQSDGLRGFYRGMSASYAGISETVIHFVIYESIKRKLIEHKANS 211

  Fly   259 HTD-----TKGSRDFLEFMMAGAVSKTIASCIAYPHEVARTRLREEGNKYNSFWQTLHTVWKEEG 318
            :.|     .|.:.||:..|:|.|.|||.|:.|||||||.||||||||:||.||:|||:.|::|||
Zfish   212 NMDDEDESVKDASDFVGMMLAAATSKTCATSIAYPHEVIRTRLREEGSKYRSFFQTLNMVFREEG 276

  Fly   319 RAGLYRGLATQLVRQIPNTAIMMATYEAVVYVL 351
            ...|||||.|.||||||||||||.|||.|||:|
Zfish   277 YRALYRGLTTHLVRQIPNTAIMMCTYELVVYLL 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rim2	NP_608615.1	Mito_carr	8..156	CDD:278578	60/147 (41%)
		Mito_carr	163..253	CDD:278578	48/91 (53%)
		Mito_carr	268..355	CDD:278578	59/84 (70%)
slc25a36a	NP_001002667.1	Mito_carr	2..113	CDD:278578	64/159 (40%)
		Solcar 1	4..108		61/150 (41%)
		PTZ00169	5..290	CDD:240302	156/331 (47%)
		Mito_carr	114..208	CDD:278578	49/93 (53%)
		Solcar 2	116..203		46/86 (53%)
		Solcar 3	224..308		58/83 (70%)
		Mito_carr	226..311	CDD:278578	59/84 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	119	1.000	Domainoid score	I5762
eggNOG	1	0.900	-	-		E1_COG4266
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10039
Inparanoid	1	1.050	313	1.000	Inparanoid score	I2555
OMA	1	1.010	-	-		QHG53601
OrthoDB	1	1.010	-	-		D1372287at2759
OrthoFinder	1	1.000	-	-		FOG0002320
OrthoInspector	1	1.000	-	-		otm24946
orthoMCL	1	0.900	-	-		OOG6_103444
Panther	1	1.100	-	-	O	PTHR45829
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1930
SonicParanoid	1	1.000	-	-		X1747
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870