Protein Alignment frtz and WDPCP

DIOPT Version :9

• Sequence 1: NP_001259879.1
• Gene: frtz / 33349
• FlyBaseID: FBgn0086698
• Length: 951
• Species: Drosophila melanogaster
• Sequence 2: XP_005264405.1
• Gene: WDPCP / 51057
• HGNCID: 28027
• Length: 781
• Species: Homo sapiens
• Alignment Length: 688
• Identity: 201/688 - (29%)
• Similarity: 345/688 - (50%)
• Gaps: 65/688 - (9%)

  Fly     3 LSETHFWTTLREDVVRIKSQDLGAFRYLRQRDKE-------QEQQDLACLAKRDYTERRNGLAVL 60
            |:|.|.|:.  ::.:.|..:|:|.::|..::|..       :::|.||  ..|||.      ..|
Human    38 LTELHLWSL--KNTLHIADRDIGIYQYYDKKDPPATEHGNLEKKQKLA--ESRDYP------WTL 92

  Fly    61 KNSGRKSTGRLKDNLKKLEDLLRQHRIIHSEWQDAAQVLLLFSHGLIAHICVDIYTGDILRMVFE 125
            ||   :...:|:|:||:||:|::..|.:.|:|::.....|||..|::  :.:.:....:.::|.:
Human    93 KN---RRPEKLRDSLKELEELMQNSRCVLSKWKNKYVCQLLFGSGVL--VSLSLSGPQLEKVVID 152

  Fly   126 KYLVGKLASEVITDAFFTRSHIVLAY-NTNQLTVVHLQRPNARS---QGPEKIANMDPRIFHVII 186
            :.|||||.|:.|:||..|.|.|:|:: ..|:|..:...:....|   :..||::.:|.:||:..|
Human   153 RSLVGKLISDTISDALLTDSFIILSFLAQNKLCFIQFTKKMESSDVNKRLEKLSALDYKIFYYEI 217

  Fly   187 PGATERKLSRHLTVNASFDLFVVWTQSSQNEVYPWRPTIRDQDRANIHVFKIKGLQLESIAYCWS 251
            ||...:...|||.:|...|..|.|.....::.:||.|...::||||:.:......:||.::...:
Human   218 PGPINKTTERHLAINCVHDRVVCWWPLVNDDAWPWAPISSEKDRANLLLLGYAQGRLEVLSSVRT 282

  Fly   252 ENDPLCVDFLRSSESQIITLEQKVSRKGDISAEICSYELAAGKMQRTAITSIPMGAQICSFAFSP 316
            |.|||.|.|......|:.|:|..||...:..|:.|.||....|:|..::|.||:.::..|...:.
Human   283 EWDPLDVRFGTKQPYQVFTVEHSVSVDKEPMADSCIYECIRNKIQCVSVTRIPLKSKAISCCRNV 347

  Fly   317 DQEKLFLGSVDRNICLHDLVQQSTKYANQIEIVPNQCAWHCDSAMLCVANERSVLQCFDLALATI 381
            .::||.||..|.::.|::..::.|..| |.|::|:..:.|...|:|.|.:.:..||.||:||:.|
Human   348 TEDKLILGCEDSSLILYETHRRVTLLA-QTELLPSLISCHPSGAILLVGSNQGELQIFDMALSPI 411

  Fly   382 GHQLVSENVTPSSLLDLSHYFVAQPTLLSVAFSRKPDLSTFKHTYAQTDCLLLLVYEQGPLACMR 446
            ..||::|:..|...|..|..|.|..:|:.:.:. .|.:.:.|...:....||.|.:|:|||..:.
Human   412 NIQLLAEDRLPRETLQFSKLFDASSSLVQMQWI-APQVVSQKGEGSDIYDLLFLRFERGPLGVLL 475

  Fly   447 IFGGTGMRGDIHNSGLTADVIADKYLRLQQPDRAVNVLAALNWETYGAMCLITLHKIANYVFFGG 511
            ...|...||.:   || .|:|. :|:...:...|:|:|:::||:|.|..|.|::..|.|::.  .
Human   476 FKLGVFTRGQL---GL-IDIIF-QYIHCDEIYEAINILSSMNWDTLGHQCFISMSAIVNHLL--R 533

  Fly   512 DQRRPRIEL-MARALKTF---AHTLSEETKDEFSDQVYDLKRRFCFYLLRKNLFAEAFEIAQDVA 572
            .:..|..|. :..:|.||   ...|.:.|..|:.||:....|||..:|||...|.:||.:|.||.
Human   534 QKLTPEREAQLETSLGTFYAPTRPLLDSTILEYRDQISKYARRFFHHLLRYQRFEKAFLLAVDVG 598

  Fly   573 DYDIFMDLYNLTKCISSLSEFAQVAFSQAAAIIHEE-----------DRANGNLSLTCDLRSESA 626
            ..|:|||::.|......|: .|:||..:|:.|..|.           ||.        |:.:|:.
Human   599 ARDLFMDIHYLALDKGELA-LAEVARKRASDIDAESITSGVELLGPLDRG--------DMLNEAF 654

  Fly   627 CSLSTCSDMLRGQGAGTAPETGLGASQPQSQQVLKNYV 664
            ..||     |..||..:.|: .|..|.|..:.:|:..:
Human   655 IGLS-----LAPQGEDSFPD-NLPPSCPTHRHILQQRI 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frtz	NP_001259879.1	DUF3312	47..596	CDD:288601	170/556 (31%)
		WD40	<308..384	CDD:295369	23/75 (31%)
WDPCP	XP_005264405.1	DUF3312	79..622	CDD:288601	173/565 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141962
Domainoid	1	1.000	239	1.000	Domainoid score	I2296
eggNOG	1	0.900	-	-		E1_28IXA
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9299
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3225
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D306370at33208
OrthoFinder	1	1.000	-	-		FOG0007139
OrthoInspector	1	1.000	-	-		oto90681
orthoMCL	1	0.900	-	-		OOG6_107800
Panther	1	1.100	-	-	LDO	PTHR13667
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7664
SonicParanoid	1	1.000	-	-		X5237
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790