DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17660 and zgc:162698

DIOPT Version :9

Sequence 1:	NP_608612.3	Gene:	CG17660 / 33347	FlyBaseID:	FBgn0031356	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001082853.2	Gene:	zgc:162698 / 560165	ZFINID:	ZDB-GENE-041111-185	Length:	583	Species:	Danio rerio

Alignment Length:	490	Identity:	229/490 - (46%)
Similarity:	311/490 - (63%)	Gaps:	52/490 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 CTSNVESNLTITFRLTEHPCIFDDRTLQAIAQNATLQKNATINNVITEITRTYPCNGLIVLAINK 124
            |.||::.| .:..::.:||                 :|...::.|.|..|:..|...    |.:|
Zfish   133 CESNIQKN-KLGLKVFDHP-----------------KKLQPLHPVTTADTKERPKRD----AEDK 175

  Fly   125 DKVVEGSAIP----TPEPKHPMLEHKHPLSPTTNPIASVKEDGIYEIEVNIAAGPSA---QFSAV 182
            .:..|.:| |    .|:.|...:|:.   |...:.:|...||..|...:.|.|...|   ::|..
Zfish   176 GQTKEAAA-PNSSNAPKSKDTSVENS---SKPPDAVARTWEDSPYMFIIKIDADSPAKDTKWSIQ 236

  Fly   183 VHIEFLGPHGFISAIDWPFLPFYLIMCIVYVIFGIIWLFVSFAQWRDLLRIQFWIGGVILLGMLE 247
            :.|:....|.:|||.:||.:.||::|||:|||..::||.:|...|||||||||||||||.|||||
Zfish   237 LEIKMKSRHEYISASEWPLMIFYMVMCIIYVIMAVLWLVLSACYWRDLLRIQFWIGGVIFLGMLE 301

  Fly   248 KAFFYAEYQTLTNKGVAVQHAELVAEFVSCAKRTLARMLVIIMSLGFGIVKPRLGPMLHRVVGVG 312
            ||.||||:|::...|.:||.|.:.||.:|..||||||:||||.|||:||||||||.:|||||.||
Zfish   302 KAVFYAEFQSIRYDGQSVQGAIMFAEVLSAVKRTLARVLVIIASLGYGIVKPRLGALLHRVVAVG 366

  Fly   313 TLYFVLACVESYLRITNVKTDRSELLVASIPLAVLDTGICWWIFTSLVQTTRTLRLRRNMVKLSL 377
            .|:.:.:.:|..||: |.:......::..|.:|::|:.|.||||.||.||.:.||||||:||||:
Zfish   367 LLFLIFSIIEGVLRV-NTEHGGQTRMICDIVMALIDSCIVWWIFISLAQTMKLLRLRRNVVKLSM 430

  Fly   378 YRHFTNTLIFAVIASVIFMLFALRLRRVENCTPGWRDIWVDTGFWHILFSVLLLVIMILWRPTNN 442
            ||||||||||||||||||:::..:...:.:|...||::|:|..||..|||.:|||||.||||:.|
Zfish   431 YRHFTNTLIFAVIASVIFIVWTAKTFHLADCKSDWRELWIDDAFWRFLFSSILLVIMFLWRPSAN 495

  Fly   443 NQRYAFTPLLDNPEDEDDEDEEDQFVADAY-GVKMRGQ----NGTPKTSTTSRNATTTEEDDLRW 502
            ||||||:||:    ||..|:||:|.:.:|: ||||||.    ||:.|.|..        ::||:|
Zfish   496 NQRYAFSPLV----DEISEEEEEQLMNEAFEGVKMRGMKPETNGSAKPSKV--------DEDLKW 548

  Fly   503 VEENIPSSMADSAL-PILDSDEEIINTKFEVSKMQ 536
            |||||||||||.|| |:|||||||:.||||:|||:
Zfish   549 VEENIPSSMADVALPPLLDSDEEIMTTKFEMSKME 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17660	NP_608612.3	Lung_7-TM_R	160..444	CDD:284280	152/286 (53%)
zgc:162698	NP_001082853.2	Lung_7-TM_R	216..497	CDD:284280	150/281 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576274
Domainoid	1	1.000	301	1.000	Domainoid score	I1388
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	393	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1448608at2759
OrthoFinder	1	1.000	-	-		FOG0001340
OrthoInspector	1	1.000	-	-		oto41432
orthoMCL	1	0.900	-	-		OOG6_101701
Panther	1	1.100	-	-	LDO	PTHR21229
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1798
SonicParanoid	1	1.000	-	-		X1432
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.930