DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cpb and capzb

DIOPT Version :9

Sequence 1:	NP_001259877.1	Gene:	cpb / 33346	FlyBaseID:	FBgn0011570	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	XP_009294020.1	Gene:	capzb / 335083	ZFINID:	ZDB-GENE-030131-7023	Length:	274	Species:	Danio rerio

Alignment Length:	271	Identity:	215/271 - (79%)
Similarity:	242/271 - (89%)	Gaps:	0/271 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEMQMDCALDLMRRLPPQQIEKNLIDLIDLAPDLCEDLLSSVDQPLKIAKDKEHGKDYLLCDYN 65
            |:|.|:|||||||||||||||||||.|||||.|.||||||||||||||||:||..||||||||||
Zfish     1 MNEQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYN 65

  Fly    66 RDGDSYRSPWSNSYYPPLEDGQMPSERLRKLEIEANYAFDQYREMYYEGGVSSVYLWDLDHGFAA 130
            ||||||||||||.|.||::||.|||.||||||:|||.||||||::|:|||||||||||||||||.
Zfish    66 RDGDSYRSPWSNKYEPPIDDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAG 130

  Fly   131 VILIKKAGDGSKMIRGCWDSIHVVEVQEKTTGRTAHYKLTSTAMLWLQTNKQGSGTMNLGGSLTR 195
            ||||||||||||.|:||||||||||||||::|||||||||||.||||||.|.|||||||||||||
Zfish   131 VILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTTKTGSGTMNLGGSLTR 195

  Fly   196 QQEQDANVSESSPHIANIGKMVEEMENKIRNTLNEIYFGKTKDIVNGLRSTQSLADQRQQAAMKQ 260
            |.|:|..||||||||||||::|||||||||:|||||||||||||||||||.:||.|.::...:::
Zfish   196 QMEKDETVSESSPHIANIGRLVEEMENKIRSTLNEIYFGKTKDIVNGLRSIESLPDNQKYRQLQR 260

  Fly   261 DLAAAILRRNV 271
            :|:..:.:|.:
Zfish   261 ELSQVLTQRQI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cpb	NP_001259877.1	F_actin_cap_B	11..239	CDD:395885	195/227 (86%)
capzb	XP_009294020.1	F_actin_cap_B	11..239	CDD:279459	195/227 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580335
Domainoid	1	1.000	423	1.000	Domainoid score	I605
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3620
Inparanoid	1	1.050	459	1.000	Inparanoid score	I1544
OMA	1	1.010	-	-		QHG54327
OrthoDB	1	1.010	-	-		D1076134at2759
OrthoFinder	1	1.000	-	-		FOG0004437
OrthoInspector	1	1.000	-	-		oto40388
orthoMCL	1	0.900	-	-		OOG6_103032
Panther	1	1.100	-	-	LDO	PTHR10619
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4497
SonicParanoid	1	1.000	-	-		X3143
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940