DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment chinmo and bcl6b

DIOPT Version :9

Sequence 1:NP_001188680.1 Gene:chinmo / 33343 FlyBaseID:FBgn0086758 Length:840 Species:Drosophila melanogaster
Sequence 2:XP_001333002.2 Gene:bcl6b / 793278 ZFINID:ZDB-GENE-120907-1 Length:550 Species:Danio rerio


Alignment Length:593 Identity:115/593 - (19%)
Similarity:181/593 - (30%) Gaps:200/593 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 SSNLAITFSNLFKSDLLADVILSCDGVVFKAHKLILAACSKKFADLFENTPT-----NGQCVIIL 74
            |:::.:..:.|...|:|.|..|.......:||..:|.|||..|..||.....     .|..:.:.
Zfish    28 SNDVLLNLNELRHRDILTDATLLVGTTKLRAHCAVLIACSGFFYTLFSRRVAGICGEQGFSLTLP 92

  Fly    75 EATTPDNMAALLEFMYKGEVHVSQEALNSFLKSAESLQVKGLSTETGRLAAQQAQQHMGDLSPLD 139
            |.....:::.||:|||...:.::...:...|.:|..||:                :|:.|     
Zfish    93 EGLDAGSVSLLLDFMYTSCLPLTPRTVPGVLTAATYLQM----------------EHVAD----- 136

  Fly   140 SPTGRRSVRNS--LSGGSSSIVPGGVGIGLGGGATGANSMSGMGIGNGLSLAGMAAGGGMAAAAN 202
              |.|..:::|  :|...|.:.|                            ....|.||.:..|:
Zfish   137 --TCRAFIQHSEGISASPSLMEP----------------------------VFRTALGGRSPPAH 171

  Fly   203 AAASSLSTLAASAN--IVDRCGSAGANIISGSAAGIGGSHSGGAGNGSGTVGIGGNGVGSGGGNN 265
            ....|.|...|.|.  |.||     |.|...|.|.:                       ..|...
Zfish   172 PTVFSPSRPTAEAEDPIPDR-----ARIPDESFASL-----------------------DPGTCQ 208

  Fly   266 GPISLGSGAGAAHHLGGSTGILKQECDSLMHPGGSSSSSGMGYTHVPPIYRPINYEPPRKRAIVR 330
            .||....              .|.|..|...|...|.|||                         
Zfish   209 TPIPKTQ--------------TKLEDSSPCTPDSPSQSSG------------------------- 234

  Fly   331 SPYSEQEQRGSVL------RDGSKSSECPSPINKPPYHRPSSSASSTAPTEADTMHSERASPQSS 389
            .|.|..|..|..|      |..||.:..|...|...|.....:.....|.:.:       .|:..
Zfish   235 QPNSPAESSGCSLSPQLKKRSESKLTPDPKACNWKKYKYIVLNPLCATPIKEE-------GPEED 292

  Fly   390 RY-ENHSPSTTAGNGNATSSLERIVKSERNNGSANEANDDDRELMDESTDNGAEDLRVKLENLKY 453
            |: :||:|.|       :..:|...|:..|..:..||..:||:::                :|.|
Zfish   293 RHSQNHAPFT-------SDRMEAASKTTNNIWNGEEAGLNDRKIL----------------SLPY 334

  Fly   454 SPPPPPNSNTS----STTPNTLLE--------NLKAD-GTLSSNLAASIAPADMLNVWNATKMNN 505
                    |||    |..|..::|        ::..| |..|..:.:.||....|...:..|..|
Zfish   335 --------NTSQQKISFAPRHVVEHTLQPLSLSISGDQGLCSPYVCSQIANQGHLLGQHPIKFEN 391

  Fly   506 KNS-------------VNTADGKKLKCLYCDRLYGYETNLRAHIRQRHQGIR-VPCPFCERTFTR 556
            .::             .:::..|..:|..|...:....||:.|.| .|.|.: ..|..|...|.:
Zfish   392 LSTQLSYIGNQGTHTKPSSSGDKPYRCNICGAQFNRPANLKTHSR-IHSGEKPYRCDTCGARFVQ 455

  Fly   557 NNTVRRHI 564
            ...:|.|:
Zfish   456 VAHLRAHV 463

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chinmoNP_001188680.1 BTB 22..116 CDD:279045 25/98 (26%)
BTB 33..116 CDD:197585 22/87 (25%)
C2H2 Zn finger 519..540 CDD:275368 6/20 (30%)
C2H2 Zn finger 547..568 CDD:275368 5/18 (28%)
bcl6bXP_001333002.2 BTB 35..146 CDD:306997 29/133 (22%)
Retinal <150..263 CDD:330657 36/207 (17%)
COG5048 386..>475 CDD:227381 16/79 (20%)
C2H2 Zn finger 418..438 CDD:275368 6/20 (30%)
C2H2 Zn finger 446..466 CDD:275368 5/18 (28%)
C2H2 Zn finger 474..494 CDD:275368
zf-H2C2_2 487..511 CDD:316026
C2H2 Zn finger 502..520 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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