DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment chinmo and ZBTB10

DIOPT Version :9

Sequence 1:NP_001188680.1 Gene:chinmo / 33343 FlyBaseID:FBgn0086758 Length:840 Species:Drosophila melanogaster
Sequence 2:NP_001099009.1 Gene:ZBTB10 / 65986 HGNCID:30953 Length:871 Species:Homo sapiens


Alignment Length:581 Identity:116/581 - (19%)
Similarity:191/581 - (32%) Gaps:170/581 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 NSFSSNLAITFSNLFKSDLLADVILSCDGVVFKAHKLILAACSKKFADLF---------ENTPTN 67
            ||:...|....:...|..:|.||.:...|.:|||||.||.|.|:.|..|:         :|..|:
Human   344 NSYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQNNTTH 408

  Fly    68 GQCVIILEATTPDNMAALLEFMYKGE-VHVSQEALN-----SFLKSAESLQVKGLSTETGRLAAQ 126
                  |:.......:.:|:|:|.|. |..||.|:.     |:|:.:|.:|              
Human   409 ------LDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQ-------------- 453

  Fly   127 QAQQHMGDLSPLDSPTGRRSVRNSLSGGSSSIVPGGVGIGLGGGATGANSMSGMGIGNGLSLAGM 191
                           |.|..::::|:....|..|..|.:....             ...::..|:
Human   454 ---------------TCRNFIKDALNISIKSEAPESVVVDYNN-------------RKPVNRDGL 490

  Fly   192 AAGGGMAAAANAAASSLSTLAASANIVDRCGSAGANIISGSAAGIGGSHSGGAGNGSGTVGIGGN 256
            ::......|:..|..:|:.||::..|    .:.|.|:..|.......:.|....:||..:     
Human   491 SSSRDQKIASFWATRNLTNLASNVKI----ENDGCNVDEGQIENYQMNDSSWVQDGSPEM----- 546

  Fly   257 GVGSGGGNNGPISLGSGAGAAHHLGGSTGILKQECDSLMHPGGSSSSSGMGYTHVPPIYRPINYE 321
                               |.:...|.|.:.      :.:..||......|.|.        ...
Human   547 -------------------AENESEGQTKVF------IWNNMGSQGIQETGKTR--------RKN 578

  Fly   322 PPRKRAIVRSPYSEQEQRGSVLRDGSKSSECPSPINKPPYHRPSSSASSTAPTEADTMHSERASP 386
            ...||.|...|.:.:..    |.|.|        :.:||...|..: :.....|.|...:..:.|
Human   579 QTTKRFIYNIPPNNETN----LEDCS--------VMQPPVAYPEEN-TLLIKEEPDLDGALLSGP 630

  Fly   387 QSSRYENHSPSTTAGNGNATSSLERIVKSERNNGSANEANDDDRELMDESTDNGAEDLRVKLENL 451
            ...|..|.:....||             :.::.|.|..::|....||                  
Human   631 DGDRNVNANLLAEAG-------------TSQDGGDAGTSHDFKYGLM------------------ 664

  Fly   452 KYSPPPPPNSNTSSTTPNTLLENLKADGTL---SSNLAASIAPADMLNVW--NATKMNNKNSVNT 511
                |.|.|.......|.|  .|....|.:   |::....:.|..    |  ..|..|.::|:..
Human   665 ----PGPSNDFKYGLIPGT--SNDFKYGLIPGASNDFKYGLLPES----WPKQETWENGESSLIM 719

  Fly   512 ADGKKLKCLYCDRLYGYETNLRAHIRQRHQGIR-VPCPFCERTFTRNNTVRRHIAREHKQE 571
               .||||.:|..:..|...|:.|: ..|.|:| ..|..|.:.|||...|:|| :..||::
Human   720 ---NKLKCPHCSYVAKYRRTLKRHL-LIHTGVRSFSCDICGKLFTRREHVKRH-SLVHKKD 775

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chinmoNP_001188680.1 BTB 22..116 CDD:279045 31/108 (29%)
BTB 33..116 CDD:197585 29/97 (30%)
C2H2 Zn finger 519..540 CDD:275368 5/20 (25%)
C2H2 Zn finger 547..568 CDD:275368 8/20 (40%)
ZBTB10NP_001099009.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..156
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 177..228
ZnF_TTF 249..>316 CDD:214739
BTB 354..460 CDD:279045 33/140 (24%)
BTB 365..461 CDD:197585 31/130 (24%)
zf-H2C2_5 722..744 CDD:290620 7/22 (32%)
C2H2 Zn finger 724..744 CDD:275368 5/20 (25%)
zf-H2C2_2 737..761 CDD:290200 8/24 (33%)
C2H2 Zn finger 752..772 CDD:275368 8/20 (40%)
zf-H2C2_2 764..787 CDD:290200 5/13 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 812..871
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.