DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment chinmo and CG34376

DIOPT Version :9

Sequence 1:	NP_001188680.1	Gene:	chinmo / 33343	FlyBaseID:	FBgn0086758	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_732741.1	Gene:	CG34376 / 42638	FlyBaseID:	FBgn0085405	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	803	Identity:	173/803 - (21%)
Similarity:	268/803 - (33%)	Gaps:	299/803 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDPQQQFCLKWNSFSSNLAITFSNLFKSDLLADVILSCDGVVFKAHKLILAACSKKFADLFENTP 65
            ||.:.:.|  |.:|..|:|..|.||:....|.||.|:|||.:..|||::||.||..|.::|...|
  Fly     1 MDDEFKLC--WKNFQDNIASGFQNLYDRGDLVDVTLACDGKLLHAHKIVLAICSPYFQEIFTTNP 63

  Fly    66 TNGQC---VIILEATTPDNMAALLEFMYKGEVHVSQEALNSFLKSAESLQVKGLSTETGRLAAQQ 127
                |   :|||:..:.:.|..||||||:|.|:|....|.||:|..:.||:|||:|.:.......
  Fly    64 ----CKHPIIILKDVSFNIMMELLEFMYQGVVNVKHTELQSFMKIGQLLQIKGLATNSNSSPGSS 124

  Fly   128 AQQHMGDLSPLDSPT----------------------------GRRSVRNSLSGGSS-------- 156
            ..:......|.:..:                            |:.:.|.:..||:|
  Fly   125 VSEKSSSQPPAEESSNTNSTNHHNSSTNSNNNSKSETDHNESKGQSNSRTTSPGGASRASNDASH 189

  Fly   157 ------------------SIVPG----------GVGIGLGGGATGANSMSGMGIGNGLS------ 187
                              ||..|          |.|...|||  |.::.:..|:.|.::
  Fly   190 LYTSNKRPMPSDFGSDSLSIYSGKQLRRSLKDHGSGGSEGGG--GDHADTAAGLDNSMNSEEFFL 252

  Fly   188 --------------LAG------------MAAGGGMAAAANAAASSLSTLAA-----SANIVDRC 221
                          |.|            ::||||.:.:..:..||.|..|.     :.|.:|
  Fly   253 PPIPQITMGEQRYDLGGLKRESDGHHHGPLSAGGGNSGSVGSLTSSASPSAPIRNPFAPNFMD-- 315

  Fly   222 GSAGANIISGSAAGIGGSHSGGAGNGSGTVGIGGNGVGSGG-GNNGPISLGSGA----------- 274
               ..|...|             ||.||..|...|.||.|| .|||.:.|||||
  Fly   316 ---SFNYYKG-------------GNSSGPSGSSNNSVGPGGVNNNGSVGLGSGAEYPNELYMPND 364

  Fly   275 ---GAAHHL---GGSTGILKQECDSLMHPGGS---------SSSSGMGYTHVPPIYRPINYEPPR 324
               ..|:|:   ...:.::.....||:|  |:         ::..||....:...||   ....|
  Fly   365 YSKSFANHMDIPSSGSNMVMLSTTSLLH--GNCVFNRNNTVATQQGMKTYWLCKSYR---ISMCR 424

  Fly   325 KRAIVRSPYSEQEQRGSVLRDGSKSSECPSPINKPPYHRPSSSASSTAPTEADTMHSERASPQSS 389
            .|.|.        ..|.::       ......|..|:.|  ....|:||:.|....:...:|.||
  Fly   425 ARCIT--------HLGRII-------SATGVHNHTPHMR--GGQGSSAPSTASVSGNPAPTPISS 472

  Fly   390 R--YENHSPSTTAGNGNATSSLERIVKSERNNGSANEANDDDRELMDESTDNGAEDLRVKLENLK 452
            :  |     |.|.|.|:....|:.  .:...|..||:...
  Fly   473 QAGY-----SLTDGGGHLGPDLQH--GNRVTNMFANQTPP------------------------- 505

  Fly   453 YSPPPPPNSNTSST-------------TPNTLLENLKADGTLSSNLAASIAPADMLNVWNATKMN 504
             .|||||....:||             .||.|:::..|...:..:
  Fly   506 -PPPPPPPLPVASTPHHPHHHHHLGQPLPNLLVQHHPAPSHMEQH-------------------- 549

  Fly   505 NKNSVNTADGKKLKCLYCDRLYGYETNLRAHIRQRHQ--GIRVPCPFCERTFTRNNTVRRHIARE 567
                     |.....|:...|...:|....|.:|.||  ....|.|                .::
  Fly   550 ---------GSSASLLHNPNLMHLQTPTHHHQQQHHQQHSPHNPPP----------------PQQ 589

  Fly   568 HKQEIGLAAGA---TIAPAHLAAAAAASAAATAAASNHSPXEAAATAAASVVMNANKEAAKQRKR 629
            |..|:|..:|:   .::||||..:..::      .|:||  :|.:....||    .::...|:::
  Fly   590 HNLELGGGSGSGAVLLSPAHLQQSPQSN------RSSHS-LQAQSPPPQSV----EEQQPHQQQQ 643

  Fly   630 KTLKMALEKCMQRRDAMVAETTT 652
                       |:::....|.||
  Fly   644 -----------QQQEGATTEVTT 655

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chinmo	NP_001188680.1	BTB	22..116	CDD:279045	41/96 (43%)
		BTB	33..116	CDD:197585	37/85 (44%)
		C2H2 Zn finger	519..540	CDD:275368	5/20 (25%)
		C2H2 Zn finger	547..568	CDD:275368	1/20 (5%)
CG34376	NP_732741.1	BTB	20..113	CDD:279045	41/96 (43%)
		BTB	31..115	CDD:197585	39/87 (45%)
		FLYWCH	390..443	CDD:282369	11/72 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9675
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020