DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment chinmo and CG8924

DIOPT Version :9

Sequence 1:	NP_001188680.1	Gene:	chinmo / 33343	FlyBaseID:	FBgn0086758	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_573091.1	Gene:	CG8924 / 32557	FlyBaseID:	FBgn0030710	Length:	514	Species:	Drosophila melanogaster

Alignment Length:	698	Identity:	134/698 - (19%)
Similarity:	217/698 - (31%)	Gaps:	279/698 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QQFCLKWNSFSSNLAITFSNLFKSDLLADVILSCDGVVFKAHKLILAACSKKFADLFENTPTNGQ 69
            |:||::|||...::...|..|.......||.|:|:|.....|:|:|||||..|..:....|....
  Fly     6 QEFCVRWNSHLGSIGAAFPQLLAGQRFVDVTLACEGQQVHCHRLVLAACSTYFEAILAEHPCKHP 70

  Fly    70 CVIILEATTPDNMAALLEFMYKGEVHVSQEALNSFLKSAESLQVKGLSTETGRLAAQQAQQHMGD 134
            .:|:........:.||::|||||||:|:|..|...|:.||.||::||......:..::.||
  Fly    71 VIILPREIKLWEIQALVDFMYKGEVNVTQAGLGQLLRCAEQLQIRGLYGSEAPINYKKLQQ---- 131

  Fly   135 LSPLDSPTGRRSVRNSLSGGSSSIVPGGVGIGLGGGATGANSMSGMGIGNGLSLAGMAAGGGMAA 199
                                                                            |
  Fly   132 ----------------------------------------------------------------A 132

  Fly   200 AANAAASSLSTLAASANIVDRCGSAGANIISGSAAGIGGSHSGGAGNGSGTVGIGGNGVGSGGGN 264
            :..||....:|.|.|...||...:..|                 |.|
  Fly   133 SLEAAKDPAATTARSFKHVDSAETDDA-----------------ATN------------------ 162

  Fly   265 NGPISLGSGAGAAHHLGGSTGILKQECDSLMHPGGSSSSSGMGYTHVPPIYRPINYEPP----RK 325
                                               |::|:.|..:..||:  |:|::.|    |:
  Fly   163 -----------------------------------STTSTTMTTSSAPPL--PVNHQQPTVLKRQ 190

  Fly   326 RAIVRSPYSEQEQRGSVLRDGSKSSECPSPINKPPYHRPSSSAS-------STAPTEADTMHSER 383
            ....|....:|:|:        :..:.|. ||.....:||.:.|       |.||||.|
  Fly   191 NPDARQQQQQQQQQ--------QVQQRPQ-INGSNAQQPSKATSTNVLGSHSNAPTEDD------ 240

  Fly   384 ASPQSSRYENHSPSTTAGNGNATSSLERIVKSERNNGSANEANDDDRELMDESTDNGAE------ 442
                              :|:...          ||.:|.....||..:..::.||...
  Fly   241 ------------------SGDEVP----------NNWNAYGEQFDDCNISAQAVDNKMNVHLSLQ 277

  Fly   443 --DLRVKLENLKYSPPPPPNSNTSSTTPNTLLENLKA--DGTLSSNLAASIAPADMLNVWNATKM 503
              .::::|:..:|.     :||....      .|..|  |....|:.|..:.....|::...|.:
  Fly   278 QARMQMQLQQQQYL-----DSNVEDD------HNYVAAHDENNDSSFATGVPCGSGLSLSLDTDL 331

  Fly   504 NNKNSVNTADGKKLKCLYCDRLYGYETNLRAHIRQRHQGIRVPCPFCERTF-TRNN-------TV 560
            :  .|.||:.|     |....:.||.:..|....:........|.....|| |.:|       |:
  Fly   332 D--TSANTSGG-----LSHSSIDGYTSYKRVRRSEASLAQAAKCVSKGETFQTVSNMFNIPVSTI 389

  Fly   561 RRHIARE---HKQEIG--------------------LAAGATIAPAH------------------ 584
            |.::||:   .|::.|                    :.|..|..|||
  Fly   390 RFYMARKGILPKRKRGRGASHAGNIIITTNSGKLSTVPASITHPPAHPHIHTNPLPHTQSQQMSM 454

  Fly   585 --------LAAAAAASAAATAAASNHSPXEAAATAAASVVMNANKEAA 624
                    :|..:.:::.|||.|::.|| ...||....|..:.:.:||
  Fly   455 DSLHLKAGIANTSGSNSPATATATSMSPSFDMATTGDIVPFHLHSDAA 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chinmo	NP_001188680.1	BTB	22..116	CDD:279045	34/93 (37%)
		BTB	33..116	CDD:197585	32/82 (39%)
		C2H2 Zn finger	519..540	CDD:275368	4/20 (20%)
		C2H2 Zn finger	547..568	CDD:275368	9/31 (29%)
CG8924	NP_573091.1	BTB	25..117	CDD:279045	33/91 (36%)
		BTB	34..117	CDD:197585	32/82 (39%)
		MerR	378..407	CDD:278788	7/28 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9675
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8160
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970