DRSC/TRiP Functional Genomics Resources

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Protein Alignment chinmo and ZBTB12

DIOPT Version :9

Sequence 1:NP_001188680.1 Gene:chinmo / 33343 FlyBaseID:FBgn0086758 Length:840 Species:Drosophila melanogaster
Sequence 2:NP_862825.1 Gene:ZBTB12 / 221527 HGNCID:19066 Length:459 Species:Homo sapiens


Alignment Length:658 Identity:119/658 - (18%)
Similarity:180/658 - (27%) Gaps:308/658 - (46%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 AITFSN---LFKSDLLADVILSCDGVVFKAHKLILAACSKKFADLFENTPTNGQCVIILEATTPD 80
            |.|..|   |...:...||.:..|.:.|:.||:||||||....|.|...|::...|.::.:..  
Human    17 AATLRNMNQLRAEERFCDVTIVADSLKFRGHKVILAACSPFLRDQFLLNPSSELQVSLMHSAR-- 79

  Fly    81 NMAALLEFMYKGEVHVSQEALNSFLKSAESLQVKGLSTETGRLAAQQAQQHMG------------ 133
            .:|.||...|.|.:..:...:.::|.:|..||::.:..:.....:|..:..:|            
Human    80 IVADLLLSCYTGALEFAVRDIVNYLTAASYLQMEHVVEKCRNALSQFIEPKIGLKEDGVSEASLV 144

  Fly   134 -DLS----------------------PLDSPTGRR------------------------------ 145
             .:|                      ||..|..|.                              
Human   145 SSISATKSLLPPARTPKPAPKPPPPPPLPPPLLRPVKLEFPLDEDLELKAEEEDEDEDEDVSDIC 209

  Fly   146 --SVRNSLSGGSSSIVPGGVGIGLG-GGATGANSMSGMGIGNGLSLAGMAAGGGMAAAANAAASS 207
              .|.::|........|||:|.||| ||:.|.:                        ....|.||
Human   210 IVKVESALEVAHRLKPPGGLGGGLGIGGSVGGH------------------------LGELAQSS 250

  Fly   208 L--STLAASANIVDRCGSAGANIISGSAAG------IGGSHSGGAGNG---SGTVGIGGNGVGSG 261
            :  ||:|....:|..|.|     :|..|.|      .||..|.||.:|   :..|.:...|.|. 
Human   251 VPPSTVAPPQGVVKACYS-----LSEDAEGEGLLLIPGGRASVGATSGLVEAAAVAMAARGAGG- 309

  Fly   262 GGNNGPISLGSGAGAAHHLGGSTGILKQECDSLMHPGGSSSSSGMGYTHVPPIYRPINYEPPRKR 326
                   |||:        |||.|.|         |||.|.                        
Human   310 -------SLGA--------GGSRGPL---------PGGFSG------------------------ 326

  Fly   327 AIVRSPYSEQEQRGSVLRDGSKSSECP---SPINKPPYHRPSSSASSTAPTEADTMHSERASPQS 388
                         |:.|:: .|.::||   ..:.|..:|..:             .|.....|:.
Human   327 -------------GNPLKN-IKCTKCPEVFQGVEKLVFHMRA-------------QHFIFMCPRC 364

  Fly   389 SRYENHSPSTTAGNGNATSSLERIVKSERNNGSANEANDDDRELMDESTDNGAEDLRVKLENLKY 453
            .:..|||     .|.|...::.|.|||.                                     
Human   365 GKQFNHS-----SNLNRHMNVHRGVKSH------------------------------------- 387

  Fly   454 SPPPPPNSNTSSTTPNTLLENLKADGTLSSNLAASIAPADMLNVWNATKMNNKNSVNTADGKKLK 518
                                                                            .
Human   388 ----------------------------------------------------------------S 388

  Fly   519 CLYCDRLYGYETNLRAHIRQRHQGIR-VPCPFCERTFTRNNTVRRHIAREHKQEIGLAAGATIAP 582
            |..|.:.:..::.|..|: ..|.|.| ..|.:|:..|.....:|||:..:|        |.|.|.
Human   389 CGICGKCFTQKSTLHDHL-NLHSGARPYRCSYCDVRFAHKPAIRRHLKEQH--------GKTTAE 444

  Fly   583 AHLAAAAA 590
            ..|.|:.|
Human   445 NVLEASVA 452

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chinmoNP_001188680.1 BTB 22..116 CDD:279045 27/96 (28%)
BTB 33..116 CDD:197585 25/82 (30%)
C2H2 Zn finger 519..540 CDD:275368 4/20 (20%)
C2H2 Zn finger 547..568 CDD:275368 6/20 (30%)
ZBTB12NP_862825.1 BTB 23..127 CDD:306997 27/105 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 153..179 3/25 (12%)
C2H2 Zn finger 335..355 CDD:275368 4/32 (13%)
zf-C2H2 359..381 CDD:306579 6/26 (23%)
COG5048 <361..>448 CDD:227381 27/201 (13%)
C2H2 Zn finger 361..381 CDD:275368 6/24 (25%)
C2H2 Zn finger 389..409 CDD:275368 4/20 (20%)
C2H2 Zn finger 417..435 CDD:275368 6/17 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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