DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chinmo and ZBTB9

DIOPT Version :9

Sequence 1:	NP_001188680.1	Gene:	chinmo / 33343	FlyBaseID:	FBgn0086758	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_689948.1	Gene:	ZBTB9 / 221504	HGNCID:	28323	Length:	473	Species:	Homo sapiens

Alignment Length:	377	Identity:	87/377 - (23%)
Similarity:	123/377 - (32%)	Gaps:	127/377 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LKWNSFSSNLAITFSNLFKSDLLADVILSCDGVVFKAHKLILAACSKKFAD--LFENTPTNGQCV 71
            :::...||:|..:.:.........||.|...|...:|||.:|||.|..|.|  |..:.|
Human    25 IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAP------ 83

  Fly    72 IILEATTP-----DNMAALLEFMYKGEVHVSQEALNSFLKSAESLQ-----------VKGLSTET 120
               ..|.|     |....||:.:|.|.:.:..:||.:.|..|..||           ::.|.|..
Human    84 ---RLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRELETSG 145

  Fly   121 GRLAAQQAQQHMGDLSPLDSPTGRRSVRNS-----LSGGSSSIVP-------GGVGIGLG----- 168
            |.::|:....:...||...| ||...:|:|     :...:|:..|       ||.|..||
Human   146 GGISARGGNSYHALLSTTSS-TGGWCIRSSPFQTPVQSSASTESPASTESPVGGEGSELGEVLQI 209

  Fly   169 -----------------GGATGANS-----MSGM---------------------GIGNGLSLAG 190
                             |.||.:.:     :||:                     |....|.|..
Human   210 QVEEEEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPLPMTATPRKLPEGESAPLELPA 274

  Fly   191 MAA--------------------GGGMAAAANAAASSLSTLAASANIVDRCGSAGANIISGSAAG 235
            ..|                    |.|    .....:...|...|....:..|..|..:.||.
Human   275 PPALPPKIFYIKQEPFEPKEEISGSG----TQPGGAKEETKVFSGGDTEGNGELGFLLPSGP--- 332

  Fly   236 IGGSHSGGAGNGSGTVGIGGNGVGSGGGNNGPISLGSGAGAAHH----LGGS 283
              |..|||.|.....|.:.||.:.||||..|      |||.|.|    |||:
Human   333 --GPTSGGGGPSWKPVDLHGNEILSGGGGPG------GAGQAVHGPVKLGGT 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chinmo	NP_001188680.1	BTB	22..116	CDD:279045	28/111 (25%)
		BTB	33..116	CDD:197585	28/100 (28%)
		C2H2 Zn finger	519..540	CDD:275368
		C2H2 Zn finger	547..568	CDD:275368
ZBTB9	NP_689948.1	BTB	38..140	CDD:306997	28/110 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	177..279		16/101 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..376		28/97 (29%)
		C2H2 Zn finger	388..405	CDD:275368
		C2H2 Zn finger	413..433	CDD:275368
		zf-C2H2	413..433	CDD:306579
		C2H2 Zn finger	440..457	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910