DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment chinmo and btbd18

DIOPT Version :9

Sequence 1:	NP_001188680.1	Gene:	chinmo / 33343	FlyBaseID:	FBgn0086758	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	XP_017951392.1	Gene:	btbd18 / 100498010	-ID:	-	Length:	602	Species:	Xenopus tropicalis

Alignment Length:	778	Identity:	142/778 - (18%)
Similarity:	223/778 - (28%)	Gaps:	273/778 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 DGVVFKAHKLILAACSKKFADLFENTPTNGQ----------C---VIILEATTPDNMAALLEFMY 90
            :|.....|..:|||||...|.|..:.....|          |   ::.:.......:..|:.:||
Frog    40 EGEGVSVHACLLAACSPYLAKLLASVTEVSQLDTDSAIQTDCTGHILTVPGIPSCYLLPLVHYMY 104

  Fly    91 KGEVHVSQEALNSFLKSAESLQV---KGLSTETGRLAAQQAQQHMGDLSPLDSPTGRRSVRNSLS 152
            ..|:.|:.|.::..|::|..||:   :||..|.|||                       ||..|
Frog   105 TSELEVTPENVHGVLEAARRLQIPELEGLRLEGGRL-----------------------VRPEL- 145

  Fly   153 GGSSSIVPGGVGIGLGGGATGANSMSGMGIGNGLSLAGMAAGGGMAAAANAAASSLSTLAASANI 217
                                 |..::....|:.:|.....:|.|.........:|
Frog   146 ---------------------ARKLNRDCFGSVISQYATESGNGKQIFTKEEITS---------- 179

  Fly   218 VDRCGSAGANIISGSAAGIGGSHSGGAGNGSGTVGIGGNGVGSGGGNNGPISLGSGAGAAHHLGG 282
                                                 |..|.......||..|.......|....
Frog   180 -------------------------------------GRNVPVRMHEQGPCILEKRTNKEHTFPA 207

  Fly   283 STGILKQECDSLMHPGGSSSSSGMGYTHVPPIYRPINYEPPRKR--AIVRSPYSEQEQRGSVLRD 345
            .||       ||:.....:|||..|....|.:  .|...|..|.  :.|::.:..:|......:|
Frog   208 DTG-------SLLRGKMEASSSLQGNIENPLL--EITKNPTEKSGPSTVQTCFQSRENYECAFQD 263

  Fly   346 GSK----------------SSECPSPINKPPYHR---PSSSASSTAPTEADTMHSERASPQSSRY 391
            ...                |||.|..:..|...|   .|...:.|.|:....|..::.......|
Frog   264 SGTTQNVSAINQDIEMTKLSSEIPLIVLNPDQKRHILVSEHGADTVPSRKTDMQDKKLFKLQRAY 328

  Fly   392 ---ENHSPSTTAGNGNATSSLERIVKSERNNGSANEANDDDRELMDESTDNGAEDLRVKLENLKY 453
               :......|.|..|.. .|.||:|.:|       ....|...|||:..|          |.|:
Frog   329 KVRKETGEQATKGKTNII-PLSRIIKLDR-------GEKQDMPQMDENIKN----------NFKH 375

  Fly   454 SPPPPPNSNTSSTTPNTLLENLKADGTLSSNLAASIAPADMLNVWNATKM--NNKNSVNTADGKK 516
                                  |.:..::|||    .|.|     :..|.  .||||
Frog   376 ----------------------KQNHNMNSNL----NPQD-----SVLKQVCRNKNS-------- 401

  Fly   517 LKCLYCDRLYGYETNLRAHIRQRHQGIRVPCPFCERTFTRNNTVRRHIAREHKQEIGLAAGATIA 581
             :|.....|.......::||:        .||..:|           |.:.|.:|     .|.:.
Frog   402 -QCTIKLELNDPSIQTQSHIQ--------VCPEQQR-----------IVQSHLEE-----NAALQ 441

  Fly   582 PAHLAAAAAASAAATAAASNHSPXEAAATAAASVVMNANKEAAKQRKRKTLKMALEKCMQRRDAM 646
            .........|...|.....:.:..........|.|||            |.|:.||:    ||.:
Frog   442 KDVCVTCVIAKPMANTLLQHKTVKVVKLQHTGSNVMN------------TKKILLEE----RDMI 490

  Fly   647 VA---ETTTGAGGD--GAEAGGESGEAVDGAGSEEGAG----SEGTEP---LTYEQQQQRMHQ-- 697
            ::   .|..|...|  ..|...:..|.|..:.:|.|..    :|...|   |:..:|..:::|
Frog   491 ISSQKRTCQGIKRDWCADEFEDKHKELVKRSKTENGHWWEEINEVESPAYALSPNEQDMQLNQPE 555

  Fly   698 ELTQQIRAAMAAEQAAEAMDSTMNTTVNTTTTTTTTTNTTGATSDGCSDAEASDGSDRPMEVD 760
            ||.:||.          ::.|..::.|:....:...|...|...|..|:::.        |:|
Frog   556 ELVEQIL----------SVSSPSSSEVDVGGQSPVPTKYVGVRPDSSSESDT--------EID 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chinmo	NP_001188680.1	BTB	22..116	CDD:279045	21/92 (23%)
		BTB	33..116	CDD:197585	21/92 (23%)
		C2H2 Zn finger	519..540	CDD:275368	4/20 (20%)
		C2H2 Zn finger	547..568	CDD:275368	4/20 (20%)
btbd18	XP_017951392.1	BTB_POZ_BTBD18	17..148	CDD:349602	31/152 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910