| Sequence 1: | NP_001356954.1 | Gene: | haf / 33339 | FlyBaseID: | FBgn0261509 | Length: | 1347 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055632.2 | Gene: | TRIL / 9865 | HGNCID: | 22200 | Length: | 811 | Species: | Homo sapiens |
| Alignment Length: | 898 | Identity: | 215/898 - (23%) |
|---|---|---|---|
| Similarity: | 331/898 - (36%) | Gaps: | 204/898 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 9 ALPAATTPLLLLLPLILGRLHVAHAQCPWQ--RDVPDLQTSC------ICAYNLGRELSVQCDQV 65
Fly 66 DFSQL------------LAAMN--THARLKPVDLLYVNNSTISELPDAVFSNL-SLHNLQLSSCG 115
Fly 116 IQRIATGAFKGQESVLRNLNLQDNLLADVPVEALKVLGKLNLLDLSKNQLSHIPDDAFVGLTKLS 180
Fly 181 TLKLNDNNVTLASNAFRGLEQSLKNLNLKGTKQRKVPESIRGLKSLAFLDLSQNGIKELPGAGGI 245
Fly 246 RVFDGLDALTALNLERNLIQSIGETAFAGVRKTLSSLSLLNNLLAEFPIGAVHSLKELRVLDIGF 310
Fly 311 NLLTSLPEAAFRGNPG-ITLLALDGNPLSSVPEGAFAHLNATLRGLSLGGRFLHCDCKL----RW 370
Fly 371 VAEWIRNGDLQVTSRERNPQFCGTPPRFRDRGFYSIQPEEL---SCPDIADAA------------ 420
Fly 421 ------LRGPVGLADNLKPTLPSSPD---------SVEYETGTGTGTVGTGTA----ASAPVTSS 466
Fly 467 VSSSTSTTT-PTTTTTTTTAEPTTRRSTTRPPTKSTTTISATTASPASNPPVNGTGTVQATSITT 530
Fly 531 SSSSSSSSSTSTGHGNGKQAPGWRQGVTNGNGNSGVGGAGGLHKPQRPPLV-------------- 581
Fly 582 ----LGYPPQRGTRIDDANEVQVKHAFRQDSSVIIQWDSDTANILG---FRVVYRLFGEK-AFKQ 638
Fly 639 GPPLESSEREFKIKNVPAQECIIVCVISLEELHVTPETVPYQQCREVRTV--ASQASNMDKITIA 701
Fly 702 ASAAICGTIIVAVIVFIAASRRSRKLQSSQQKSPLPIGGLPVNCCGPTGSPGPLGSIAT-----L 761
Fly 762 SAFNNHKEWDQVSAYSGRSIPRPRIYPVEQPDD--MRSHFSGMPGKVGKSRSL 812 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| haf | NP_001356954.1 | LRR | <52..>252 | CDD:227223 | 55/214 (26%) |
| leucine-rich repeat | 86..105 | CDD:275380 | 5/19 (26%) | ||
| leucine-rich repeat | 106..129 | CDD:275380 | 7/22 (32%) | ||
| LRR_8 | 131..189 | CDD:338972 | 19/57 (33%) | ||
| leucine-rich repeat | 131..154 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 155..178 | CDD:275380 | 7/22 (32%) | ||
| leucine-rich repeat | 179..202 | CDD:275380 | 5/22 (23%) | ||
| leucine-rich repeat | 203..225 | CDD:275380 | 2/21 (10%) | ||
| leucine-rich repeat | 226..253 | CDD:275380 | 10/26 (38%) | ||
| LRR_8 | 254..337 | CDD:338972 | 27/83 (33%) | ||
| leucine-rich repeat | 254..302 | CDD:275380 | 14/47 (30%) | ||
| leucine-rich repeat | 303..326 | CDD:275380 | 9/22 (41%) | ||
| leucine-rich repeat | 327..350 | CDD:275380 | 7/22 (32%) | ||
| PCC | 332..>413 | CDD:188093 | 25/87 (29%) | ||
| PRK10927 | <1061..>1097 | CDD:236797 | |||
| TRIL | NP_055632.2 | LRR_RI | <2..194 | CDD:238064 | 46/181 (25%) |
| leucine-rich repeat | 37..61 | CDD:275380 | 7/25 (28%) | ||
| LRR 1 | 61..81 | 5/19 (26%) | |||
| leucine-rich repeat | 62..84 | CDD:275380 | 6/21 (29%) | ||
| LRR_8 | 84..143 | CDD:290566 | 9/58 (16%) | ||
| LRR 2 | 84..105 | 1/20 (5%) | |||
| leucine-rich repeat | 85..108 | CDD:275380 | 2/22 (9%) | ||
| LRR 3 | 108..129 | 4/20 (20%) | |||
| leucine-rich repeat | 109..132 | CDD:275380 | 5/22 (23%) | ||
| LRR 4 | 132..153 | 6/20 (30%) | |||
| leucine-rich repeat | 133..156 | CDD:275380 | 7/22 (32%) | ||
| LRR_8 | 156..215 | CDD:290566 | 20/69 (29%) | ||
| LRR 5 | 156..177 | 6/21 (29%) | |||
| leucine-rich repeat | 157..180 | CDD:275380 | 6/23 (26%) | ||
| LRR 6 | 180..201 | 6/20 (30%) | |||
| leucine-rich repeat | 181..204 | CDD:275380 | 7/22 (32%) | ||
| LRR 7 | 204..223 | 8/39 (21%) | |||
| leucine-rich repeat | 205..254 | CDD:275380 | 19/73 (26%) | ||
| LRR 8 | 230..251 | 10/24 (42%) | |||
| LRR_8 | 239..289 | CDD:290566 | 17/54 (31%) | ||
| LRR_RI | <249..>364 | CDD:238064 | 38/117 (32%) | ||
| LRR 9 | 254..275 | 6/20 (30%) | |||
| leucine-rich repeat | 255..278 | CDD:275380 | 7/23 (30%) | ||
| LRR 10 | 278..299 | 6/20 (30%) | |||
| LRR_8 | 279..337 | CDD:290566 | 20/58 (34%) | ||
| leucine-rich repeat | 279..302 | CDD:275380 | 7/22 (32%) | ||
| LRR 11 | 302..323 | 8/21 (38%) | |||
| leucine-rich repeat | 303..326 | CDD:275380 | 9/23 (39%) | ||
| LRR 12 | 326..347 | 6/20 (30%) | |||
| leucine-rich repeat | 327..346 | CDD:275380 | 5/18 (28%) | ||
| leucine-rich repeat | 351..363 | CDD:275378 | 4/12 (33%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 484..549 | 16/67 (24%) | |||
| fn3 | 589..667 | CDD:278470 | 18/97 (19%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 93 | 1.000 | Inparanoid score | I5085 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.960 | |||||