DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment haf and RLP15

DIOPT Version :9

Sequence 1:	NP_001356954.1	Gene:	haf / 33339	FlyBaseID:	FBgn0261509	Length:	1347	Species:	Drosophila melanogaster
Sequence 2:	NP_177559.1	Gene:	RLP15 / 843759	AraportID:	AT1G74190	Length:	965	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	126/567 - (22%)
Similarity:	197/567 - (34%)	Gaps:	175/567 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LLLLPLILGRLHVAHAQC--------------------------PWQRDVPDLQTSCICAYNLGR 56
            |:.:.|::|:|| .:..|                          .|..|.    ||..|.:.
plant    11 LIWVMLLMGQLH-GYKSCIDEEKIALFELRKHMISRTESESVLPTWTNDT----TSDCCRWK--- 67

  Fly    57 ELSVQCD-------QVDFSQLLAAMNTHARL------KPVDLLYVNNSTISELPDAVFSNLSLHN 108
              .|.|:       ::.|..|....|:...|      :.|..|.:::|..|.|.|.|....||..
plant    68 --GVACNRVSGRVTEISFGGLSLKDNSLLNLSLLHPFEDVRSLNLSSSRCSGLFDDVEGYKSLRK 130

  Fly   109 LQLSSCGIQRIATGAFKGQ-------ESVLRNLNLQ-DNLLADVPVEALKVLGKLNLLDLSKNQL 165
            |:  ...|..:|:..|...       .:.|..|.|: :|:....|.:.|:.|..|.|||||:|:.
plant   131 LR--KLEILDLASNKFNNSIFHFLSAATSLTTLFLRSNNMDGSFPAKELRDLTNLELLDLSRNRF 193

  Fly   166 S-HIPDDAFVGLTKLSTLKLNDN-------------------------------NVTLASNAFRG 198
            : .||......|.||..|.|:.|                               .:.|:.|...|
plant   194 NGSIPIQELSSLRKLKALDLSGNEFSGSMELQGKFCTDLLFSIQSGICELNNMQELDLSQNKLVG 258

  Fly   199 -LEQSLKNL-----------NLKGTKQRKVPESIRGLKSLAFLDLSQNGIKELPGAGGIRVFDGL 251
             |...|.:|           .|.||    ||.|:..|:||.:|.|..|   :..|:........|
plant   259 HLPSCLTSLTGLRVLDLSSNKLTGT----VPSSLGSLQSLEYLSLFDN---DFEGSFSFGSLANL 316

  Fly   252 DALTALNL--ERNLIQSIGETAFAGVRKTLSSLSLLNNLLAEFPIGAVHSLKELRVLDIGFNLLT 314
            ..|..|.|  :.:.:|.:.|:::. .:..||.::|.:..:.:.|...:|. |:||.:|:..|.::
plant   317 SNLMVLKLCSKSSSLQVLSESSWK-PKFQLSVIALRSCNMEKVPHFLLHQ-KDLRHVDLSDNNIS 379

  Fly   315 -SLPEAAFRGNPGITLLALDGNPLSS--VPEGA------------FAHLNATLRGLSLGGRFLHC 364
             .||......|..:.:|.|..|..:|  :|:.|            |.||...    ::|..|.|
plant   380 GKLPSWLLANNTKLKVLLLQNNLFTSFQIPKSAHNLLFLDVSANDFNHLFPE----NIGWIFPH- 439

  Fly   365 DCKLRWVAEWIRN------------GDLQVTSRERNPQFCGTPPRFRDRGFYSIQPEELSCPDIA 417
               ||::.....|            ..:|.....|| .|.|..||....|.||:...:||
plant   440 ---LRYLNTSKNNFQENLPSSLGNMNGIQYMDLSRN-SFHGNLPRSFVNGCYSMAILKLS----- 495

  Fly   418 DAALRGPVGLADNLKPTLPSSPDSVEYETGTG--------TGTVGTG 456
            ...|.|.:            .|:|..:....|        ||.:|.|
plant   496 HNKLSGEI------------FPESTNFTNILGLFMDNNLFTGKIGQG 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
haf	NP_001356954.1	LRR	<52..>252	CDD:227223	60/264 (23%)
		leucine-rich repeat	86..105	CDD:275380	6/18 (33%)
		leucine-rich repeat	106..129	CDD:275380	5/29 (17%)
		LRR_8	131..189	CDD:338972	22/90 (24%)
		leucine-rich repeat	131..154	CDD:275380	7/23 (30%)
		leucine-rich repeat	155..178	CDD:275380	10/23 (43%)
		leucine-rich repeat	179..202	CDD:275380	8/54 (15%)
		leucine-rich repeat	203..225	CDD:275380	9/32 (28%)
		leucine-rich repeat	226..253	CDD:275380	6/26 (23%)
		LRR_8	254..337	CDD:338972	21/85 (25%)
		leucine-rich repeat	254..302	CDD:275380	10/49 (20%)
		leucine-rich repeat	303..326	CDD:275380	7/23 (30%)
		leucine-rich repeat	327..350	CDD:275380	9/36 (25%)
		PCC	332..>413	CDD:188093	25/106 (24%)
		PRK10927	<1061..>1097	CDD:236797
RLP15	NP_177559.1	LRRNT_2	28..72	CDD:369783	6/52 (12%)
		PLN00113	<105..>287	CDD:215061	46/187 (25%)
		leucine-rich repeat	106..133	CDD:275380	9/28 (32%)
		leucine-rich repeat	134..157	CDD:275380	3/22 (14%)
		leucine-rich repeat	158..182	CDD:275380	7/23 (30%)
		leucine-rich repeat	183..207	CDD:275380	10/23 (43%)
		leucine-rich repeat	208..245	CDD:275380	4/36 (11%)
		leucine-rich repeat	246..269	CDD:275380	6/22 (27%)
		PLN00113	249..>892	CDD:215061	74/317 (23%)
		leucine-rich repeat	270..293	CDD:275380	7/26 (27%)
		leucine-rich repeat	294..318	CDD:275380	6/26 (23%)
		leucine-rich repeat	319..357	CDD:275380	8/38 (21%)
		leucine-rich repeat	368..392	CDD:275380	7/23 (30%)
		leucine-rich repeat	440..463	CDD:275380	3/22 (14%)
		leucine-rich repeat	465..488	CDD:275380	8/23 (35%)
		leucine-rich repeat	489..512	CDD:275380	6/39 (15%)
		leucine-rich repeat	513..536	CDD:275380	5/18 (28%)
		leucine-rich repeat	537..560	CDD:275380
		leucine-rich repeat	561..584	CDD:275380
		leucine-rich repeat	585..607	CDD:275380
		leucine-rich repeat	608..629	CDD:275380
		leucine-rich repeat	630..652	CDD:275380
		leucine-rich repeat	653..676	CDD:275380
		leucine-rich repeat	677..697	CDD:275380
		leucine-rich repeat	744..804	CDD:275380
		leucine-rich repeat	749..780	CDD:275380
		leucine-rich repeat	805..828	CDD:275380
		leucine-rich repeat	829..850	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910