| Sequence 1: | NP_001356954.1 | Gene: | haf / 33339 | FlyBaseID: | FBgn0261509 | Length: | 1347 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001123608.1 | Gene: | ISLR2 / 57611 | HGNCID: | 29286 | Length: | 745 | Species: | Homo sapiens |
| Alignment Length: | 794 | Identity: | 160/794 - (20%) |
|---|---|---|---|
| Similarity: | 245/794 - (30%) | Gaps: | 260/794 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 214 RKVPESIRGLKSLAFLDLSQNGIKEL-PGAGGIRVFDGLDALTALNLERNLIQSIGETAFAGVRK 277
Fly 278 TLSSLSLLNNLLAEFPIGAVHSLKELRVLDIGFNLLTSLPEAAFRGNPGITLLALDGNPLSSVPE 342
Fly 343 GAFAHLNATLRGLSLGGRFLHCDCKLRWVAEWIRNGDLQVTSRERNPQFCGTPPRFRDRGFYSIQ 407
Fly 408 PEELSCPDI---ADAALRGP-----VGLADNL--------------------------KPTLPSS 438
Fly 439 PDSV--EYETGTGTGTVGTGTAASAPV-------------------------------------- 463
Fly 464 --------TSSVSSSTSTTTPTTTTTTTTAEPTTRRSTTRPPTKSTTTISATTASPASNP--PVN 518
Fly 519 GTGTVQATSITTSSSSSSSSSTSTGHGNGKQA---PGWRQGVTNGNGN----------------- 563
Fly 564 ----------------------------SGVGGAGGLHKPQRPPLVLGYPPQRGTRIDDANEVQV 600
Fly 601 KHAFRQDSSVIIQWD--SDTANILGFRVVYRLFGEKAFKQGPPLESSEREFKIKNVPAQECIIVC 663
Fly 664 VISLEELHVTPETVPYQQCREVRTVASQASNMDKITIAASAAICGTIIVAVIVFIAASRRSRKLQ 728
Fly 729 SS----QQKSPLPIGGLPVNCCGPTGSPGPLGS-IATLSAFNNHKEWDQVSAYSGRSIPRPRIYP 788
Fly 789 V------EQPDDMRSHFSGMPGKVGKSRSLADGQSQHSFSNNSHRGYLGSAFPSNLVNSRPELRQ 847
Fly 848 SRQSLAAASERMSR 861 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| haf | NP_001356954.1 | LRR | <52..>252 | CDD:227223 | 13/38 (34%) |
| leucine-rich repeat | 86..105 | CDD:275380 | |||
| leucine-rich repeat | 106..129 | CDD:275380 | |||
| LRR_8 | 131..189 | CDD:338972 | |||
| leucine-rich repeat | 131..154 | CDD:275380 | |||
| leucine-rich repeat | 155..178 | CDD:275380 | |||
| leucine-rich repeat | 179..202 | CDD:275380 | |||
| leucine-rich repeat | 203..225 | CDD:275380 | 4/10 (40%) | ||
| leucine-rich repeat | 226..253 | CDD:275380 | 9/27 (33%) | ||
| LRR_8 | 254..337 | CDD:338972 | 25/82 (30%) | ||
| leucine-rich repeat | 254..302 | CDD:275380 | 14/47 (30%) | ||
| leucine-rich repeat | 303..326 | CDD:275380 | 8/22 (36%) | ||
| leucine-rich repeat | 327..350 | CDD:275380 | 6/22 (27%) | ||
| PCC | 332..>413 | CDD:188093 | 21/80 (26%) | ||
| PRK10927 | <1061..>1097 | CDD:236797 | |||
| ISLR2 | NP_001123608.1 | leucine-rich repeat | 36..52 | CDD:275380 | 4/10 (40%) |
| LRR_8 | 52..109 | CDD:404697 | 19/62 (31%) | ||
| LRR 1 | 52..73 | 9/25 (36%) | |||
| leucine-rich repeat | 53..76 | CDD:275380 | 9/27 (33%) | ||
| LRR 2 | 76..97 | 6/21 (29%) | |||
| leucine-rich repeat | 77..100 | CDD:275380 | 7/23 (30%) | ||
| LRR_8 | 99..159 | CDD:404697 | 18/59 (31%) | ||
| LRR 3 | 100..123 | 6/22 (27%) | |||
| leucine-rich repeat | 101..124 | CDD:275380 | 7/22 (32%) | ||
| LRR 4 | 124..145 | 8/20 (40%) | |||
| leucine-rich repeat | 125..148 | CDD:275380 | 8/22 (36%) | ||
| LRR 5 | 148..169 | 5/20 (25%) | |||
| leucine-rich repeat | 149..172 | CDD:275380 | 6/22 (27%) | ||
| PCC | 154..>228 | CDD:188093 | 21/76 (28%) | ||
| Ig_3 | 232..359 | CDD:404760 | 20/126 (16%) | ||
| Ig strand B | 256..263 | CDD:409353 | 1/6 (17%) | ||
| Ig strand C | 269..274 | CDD:409353 | 0/4 (0%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 287..326 | 11/38 (29%) | |||
| Ig strand C' | 305..307 | CDD:409353 | 0/1 (0%) | ||
| Ig strand D | 331..335 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 338..343 | CDD:409353 | 0/4 (0%) | ||
| Ig strand F | 351..359 | CDD:409353 | 0/7 (0%) | ||
| Ig strand G | 362..372 | CDD:409353 | 1/9 (11%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 375..466 | 23/94 (24%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 656..722 | 16/81 (20%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24366 |
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 1.100 | |||||